Home Tools
Log in
Products Inhibitors Libraries Recombinant Proteins Kits Services Contact Us
Cart
Peptides Monoclonal Antibodies Dye Reagents PROTAC Virtual Screening TargetMol Kits Cell Counting Kit-8 (CCK-8) Inhibitor Cocktails Natural Products Phenols Alkaloids Flavonoids
Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
TargetMol
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Search Result

Search Results for " ly3 "

Targets

5-HT Receptor

49

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T4266 LY334370 LY 334370 5-HT Receptor
LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM
T7810 LY3177833 LY-3177833 CDK
LY3177833 is an Cdc7 kinase inhibitor (IC50 : 3.3 nM)
T5125 LY3200882 TGF-beta/Smad
LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).
T9064 LY3143921 hydrate CDK
LY3143921 ((S)-Example 2) hydrate is an orally active CDC7 kinase inhibitor with broad in vitro anticancer activity [1].
T15816 LY341495 GluR
LY341495 is a potent metabotropic glutamate receptor antagonist that exhibits high activity against a wide range of glutamate receptor subtypes and can be used for the study of neurological disorders.
T61661 LY3372689 Formulaic Ia Microtubule Associated
LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.
T15815 LY3295668 AK-01 Aurora Kinase
LY3295668 (AK-01) is a selective inhibitor of Aurora A with Kis of 0.8 nM and 1038 nM for Aurora A and B, respectively.
T6882 LY3009120 DP-4978 Raf , Autophagy
LY3009120 (DP-4978) is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for A-raf, B-Raf, and C-Raf in A375 cells, respectively. Phase 1.
T15819 LY377604 Adrenergic Receptor
LY377604 is a human β3-adrenergic receptor agonist (EC50: 2.4 nM) and β1/2-adrenergic receptor antagonist for the study of obesity.
T9078 LY3405105 1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester CDK
LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester) is a novel CDK7 inhibitors.
T27949 LY382884 LY-382884,LY 382884 GluR
LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.
T27951 LY392098 LY-392098,LY 392098,AMPA receptor modulator-3 GluR , iGluR
LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.
T27947L LY339434 HCl LY339434 HCl(219566-62-8 Free base) GluR , NMDAR
LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA) receptors.
T2688 LY310762 LY310762 HCl 5-HT Receptor
LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM.
T78626 LY393615 NCC1048 Calcium Channel
LY393615 (NCC1048) is a novel blocker of both neuronal Ca²⁺ (calcium) and Na⁺ (sodium) channels, exhibiting half-maximal inhibitory concentrations (IC₅₀) of 1.9 µM and 5.2 µM against α1A and α1B calcium channel subunits,...
T27942 LY307452 LY 307452,LY-307452
LY307452 is a selective antagonist of mGluR2/3.
T11912 LY3154207 Others
LY3154207 is a subtype selective, potent, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM).
T18246 Mal-C2-Gly3-EDA-PNU-159682 Others
Mal-C2-Gly3-EDA-PNU-159682, a drug-linker conjugate for antibody-drug conjugates (ADC), combines the cleavable ADC linker Mal-C2-Gly3-EDA with the potent ADC cytotoxin PNU-159682.
T27945 LY320954 LY 320954,PDSP1_001629,LY-320954
LY320954 is an antagonist of 5-HT2A receptor.
T27940 LY301875 LY 301875,LY-301875
LY301875 is an antagonist of nonpeptide angiotensin receptor.
T11911 LY3020371 hydrochloride GluR
LY3020371 hydrochloride exerts an antidepressant-like signature in vivo. LY3020371 hydrochloride is a potent, selective metabotropic glutamate 2/3 receptor (mGlu2/3) antagonist with Ki of 5.3 and 2.5 nM, potently blocks ...
T77828 Fmoc-Gly3-Val-Cit-PAB
Fmoc-Gly3-Val-Cit-PAB is a cleavable linker utilized in the assembly of antibody-drug conjugates (ADCs).
T60747 LY3143921
LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].
T82384 Fmoc-Gly3-VC-PAB-MMAE
Fmoc-Gly3-VC-PAB-MMAE is a drug-linker conjugate utilized in antibody-drug conjugates (ADCs), composed of the potent cytotoxic agent Monomethyl auristatin E (MMAE) tethered via a cleavable linker [1].
T27943 LY314228 LY-314228,LY 314228
LY314228 is an antagonist of 5-HT2A receptor.
T62610 LY3154885
LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).
T38792 LY3027788 LY3027788
LY3027788, a diester analog of LY3020371, an mGlu2/3 receptor antagonist, is a highly potent and orally active prodrug of LY3020371. Notably, LY3027788 exhibits significant antidepressant efficacy.
T15813 LY309887 LTR
LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.
T15814 LY3130481 Others
LY3130481 is an AMPA receptor antagonist. It is dependent upon transmembrane AMPA receptor regulatory protein (TARP) γ-8 and selectively inhibits AMPA/TARP γ-8 (IC50: 65 nM).
T15818 LY367385 FXR
LY367385 is a highly effective and selective mGluR1a antagonist. LY367385 has neuroprotective, anticonvulsant, and antiepileptic effects. Compared with > 100 μM for mGlu5a, LY367385 has an IC50 of 8.8 μM for inhibits of ...
T27941 LY303336 LY-303336,LY 303336
LY303336 is an antagonist of AT1 receptor.
T24422 LY3104607 LY 3104607,LY-3104607
LY3104607 is a G Protein-Coupled Receptor 40 agonist. It is active in oral treatment for patients with type 2 diabetes mellitus and is a glucose-lowering drug candidate.
T60355 LY367385 hydrochloride
LY367385 hydrochloride is a potent and selective mGluR1a antagonist with an IC50 value of 8.8 μM for inhibiting quisqualate-induced phosphoinositide (PI) hydrolysis, showing significantly higher selectivity compared to i...
T33013 LY334362 LY 334362,LY-334362
LY334362 is a bioactive chemical.
T27947 LY339434 LY 339434,LY-339434
LY339434 is a potent and selective agonist of the kainate receptor GluK1, GluR5.
T22951 LY320135 LY 320135 Others
CB1 receptor antagonist/inverse agonist
T39406 (±)-LY367385 (±)-LY367385
(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 exhibits a high inhibitory activity against quisqualate-induced phosphoinositide (PI) hydrolysis, w...
T72384 (S)-LY3177833 hydrate
(S)-LY3177833 ((S)-Example 2) hydrate, an orally active CDC7 kinase inhibitor, exhibits extensive in vitro anticancer efficacy.
T70005 LY3325656
LY3325656 is a GPR142 agonist suitable for clinical testing in human. LY3325656 demonstrated anti-diabetic benefits in pre-clinical studies and ADME/PK properties suitable for human dosing. LY3325656 is the first GPR1...
T38791 LY3020371
LY3020371 is a highly potent and selective antagonist targeting the glutamate (mGlu) 2/3 receptor, showcasing excellent inhibition at Ki values of 5.26 nM and 2.50 nM for hmGluR2 and hmGluR3, respectively. With its remar...
T38790 LY3027788 hydrochloride
LY3027788 hydrochloride is a diester analog of LY3020371, a selective antagonist of the metabotropic glutamate 2 and 3 receptors (mGlu2/3). It serves as a highly potent and orally bioavailable prodrug of LY3020371. Notab...
T27944 LY3202626 LY 3202626,LY-3202626
LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.
T27950 LY389795 LY-389795,LY 389795
LY389795 is an agonist of group II (mGlu2/3) metabotropic glutamate receptor, it is used in inflammatory pain models.
T61610 NPEC-caged-LY379268
NPEC-caged-LY379268 is a type II mGluR agonist [1].
T18247 Mal-C2-Gly3-EDA Others
Mal-C2-Gly3-EDA is a cleavable antibody-drug conjugate (ADC) linker equipped with a Maleimide moiety. It serves the purpose of facilitating the synthesis of ADCs.
T40308 Gly3-VC-PAB-MMAE Gly3-VC-PAB-MMAE
Gly3-VC-PAB-MMAE is a chemical compound comprised of a cleavable antibody-drug conjugate (ADC) linker, Gly3-VC-PAB, and a potent inhibitor of tubulin, MMAE. It is utilized in the synthesis of ADCs.
T63053 MALT1-IN-3
MALT1-IN-3 is a potent inhibitor of MALT1 protease (IC50: 0.06 μM) with IC50 values of 0.14 and 0.13 μM for human IL6 and IL10, respectively, in OCI-LY3 cells.
T62533 MALT1-IN-8
MALT1-IN-8 is a potent inhibitor of MALT1 protease (IC50: 2 nM). MALT1-IN-8 inhibits the growth of OCI-LY3 lymphoma cells (IC50: 1.16 μM) and exhibits anticancer activity.
T63051 (R)-MALT1-IN-3
(R)-MALT1-IN-3 (compound 121) is a potent inhibitor of MALT1 protease (IC50: 20 nM) with IC50 values of 60 nM and 40 nM for human IL6/IL10 in OCI-LY3 cells, respectively.

Compounds

LY334370
T4266
Synonym: LY 334370
Target: 5-HT Receptor
LY3177833
T7810
Synonym: LY-3177833
Target: CDK
LY3200882
T5125
Synonym:
Target: TGF-beta/Smad
LY3143921 hydrate
T9064
Synonym:
Target: CDK
LY341495
T15816
Synonym:
Target: GluR
LY3372689
T61661
Synonym: Formulaic Ia
Target: Microtubule Associated
LY3295668
T15815
Synonym: AK-01
Target: Aurora Kinase
LY3009120
T6882
Synonym: DP-4978
Target: Raf, Autophagy
LY377604
T15819
Synonym:
Target: Adrenergic Receptor
LY3405105
T9078
Synonym: 1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester
Target: CDK
LY382884
T27949
Synonym: LY-382884,LY 382884
Target: GluR
LY392098
T27951
Synonym: LY-392098,LY 392098,AMPA receptor modulator-3
Target: GluR, iGluR
LY339434 HCl
T27947L
Synonym: LY339434 HCl(219566-62-8 Free base)
Target: GluR, NMDAR
LY310762
T2688
Synonym: LY310762 HCl
Target: 5-HT Receptor
LY393615
T78626
Synonym: NCC1048
Target: Calcium Channel
LY307452
T27942
Synonym: LY 307452,LY-307452
Target:
LY3154207
T11912
Synonym:
Target: Others
Mal-C2-Gly3-EDA-PNU-159682
T18246
Synonym:
Target: Others
LY320954
T27945
Synonym: LY 320954,PDSP1_001629,LY-320954
Target:
LY301875
T27940
Synonym: LY 301875,LY-301875
Target:
LY3020371 hydrochloride
T11911
Synonym:
Target: GluR
Fmoc-Gly3-Val-Cit-PAB
T77828
Synonym:
Target:
LY3143921
T60747
Synonym:
Target:
Fmoc-Gly3-VC-PAB-MMAE
T82384
Synonym:
Target:
LY314228
T27943
Synonym: LY-314228,LY 314228
Target:
LY3154885
T62610
Synonym:
Target:
LY3027788
T38792
Synonym: LY3027788
Target:
LY309887
T15813
Synonym:
Target: LTR
LY3130481
T15814
Synonym:
Target: Others
LY367385
T15818
Synonym:
Target: FXR
LY303336
T27941
Synonym: LY-303336,LY 303336
Target:
LY3104607
T24422
Synonym: LY 3104607,LY-3104607
Target:
LY367385 hydrochloride
T60355
Synonym:
Target:
LY334362
T33013
Synonym: LY 334362,LY-334362
Target:
LY339434
T27947
Synonym: LY 339434,LY-339434
Target:
LY320135
T22951
Synonym: LY 320135
Target: Others
(±)-LY367385
T39406
Synonym: (±)-LY367385
Target:
(S)-LY3177833 hydrate
T72384
Synonym:
Target:
LY3325656
T70005
Synonym:
Target:
LY3020371
T38791
Synonym:
Target:
LY3027788 hydrochloride
T38790
Synonym:
Target:
LY3202626
T27944
Synonym: LY 3202626,LY-3202626
Target:
LY389795
T27950
Synonym: LY-389795,LY 389795
Target:
NPEC-caged-LY379268
T61610
Synonym:
Target:
Mal-C2-Gly3-EDA
T18247
Synonym:
Target: Others
Gly3-VC-PAB-MMAE
T40308
Synonym: Gly3-VC-PAB-MMAE
Target:
MALT1-IN-3
T63053
Synonym:
Target:
MALT1-IN-8
T62533
Synonym:
Target:
(R)-MALT1-IN-3
T63051
Synonym:
Target:

Recombinant Proteins

Species：
Human (3)
Expression System：
HEK293 Cells (3)
Tag：
Tag Free (2)
C-hFc (1)
Cat No. Product Name Species Expression System
TMPY-04925 CD8 beta Protein, Human, Recombinant, Biotinylated Human HEK293 Cells
CD8 beta Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.
TMPY-02925 CD8 beta Protein, Human, Recombinant Human HEK293 Cells
CD8 beta Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.
TMPY-02703 CD8 beta Protein, Human, Recombinant (hFc) Human HEK293 Cells
CD8 beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44 kDa and the accession number is P10966-1.
CORPORATE
About Us Careers Privacy Notice Events & News Terms & Conditions
SUPPORT
Contact Us Worldwide Distributors Quality Control Technical Support
RESOURCE
Product Catalog Product Citations Signaling Pathways Solution Calculators
FOLLOW OUR
Social Network
Newsletter Subscription
Subscribe to receive our lastest product updates and special offers!
Corporate
Support
Resource
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
TargetMol
Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved.