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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T74878 | Enzyme-IN-1 | ||
Enzyme-IN-1 (compound 1), a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases, specifically targets and inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. This compound may possess pot... | |||
T13244 | Ubiquitination-IN-1 | Others | |
Ubiquitination-IN-1 is an inhibitor of ubiquitination and Cksl-Skp2 protein-protein interaction (IC50: 0.17 μM). | |||
T9564 | IRE1α kinase-IN-1 | IRE1 | |
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosph... | |||
T9089 | FTO-IN-1 | UUN44923 | Others |
UUN44923 is a FTO inhibitor. It may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS) , type 2 diabetes (T2D) , Alzheimer's diseases, breast cancers, small- cell lung cancers, a h... | |||
T8218 | Vanin-1-IN-1 | VUN34002 | Others |
Vanin-1-IN-1 (VUN34002) is an vanin-1 enzyme inhibitor. | |||
T75349 | CDP-Star | ||
CDP-Star, a chemiluminescent substrate specifically designed for alkaline phosphatase, is effectively utilized in enzyme-linked immunoassays (ELISA) [1]. | |||
T1869 | PluriSIn 1 | NSC 14613,PluriSIn #1,PluriSln 1 | Apoptosis , Dehydrogenase , Stearoyl-CoA Desaturase (SCD) |
PluriSIn 1 (NSC 14613) is an inhibitor of stearoyl-CoA desaturase (SCD1), the key enzyme in oleic acid biosynthesis, revealing a unique role for lipid metabolism in hPSCs. | |||
T3161L | BACE-IN-1 acetate | BACE-IN-1 acetate (350228-37-4,Free base) | BACE |
BACE-IN-1 acetate (BACE-IN-1 acetate (350228-37-4,Free base)) has been used as β-site amyloid precursor protein (APP) cleaving enzyme-1 (BACE1) inhibitor in BACE1 inhibitor assay. β-Site amyloid precursor protein (APP) c... | |||
T64354 | Cystathionine-γ-lyase-IN-1 | SHIP-2a | Others |
Cystathionine-γ-lyase-IN-1 (SHIP-2a) is a selective inhibitor of cystathionine γ-lyase (CSE) enzyme (IC50= 6.3 μM). | |||
T9627 | PHD-1-IN-1 | HIF/HIF Prolyl-Hydroxylase | |
PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM). | |||
T11267 | FASN-IN-1 | TVB-2460 | Fatty Acid Synthase |
FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme involved in fatty acid synthesis, potentially disrupting fatt... | |||
T82008 | JG-2016 | Histone Acetyltransferase | |
JG-2016, as a small molecule histone acetyltransferase 1 (HAT1) inhibitor, inhibits the growth of human cancer cell lines, inhibits enzyme activity in cellulose, and interferes with tumor growth. | |||
T60219 | ELOVL1-IN-3 | Others | |
ELOVL1-IN-3 is a potent and orally active inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme. ELOVL1-IN-3 serves as a useful tool for researching adrenoleukodystrophy (ALD). | |||
T0617 | Nicotinamide N-oxide | Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide | c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite |
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of n... | |||
TN2190 | Scoulerine | Apoptosis , Beta-Secretase , BACE , Parasite | |
Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells. | |||
T5199 | COH000 | E1/E2/E3 Enzyme | |
COH000 is a covalent and irreversible inhibitor of small ubiquitin-like modifier (SUMO)-activating enzyme and inhibited SUMOylation (IC50: ~ 0.2 μM in vitro). | |||
T6S0923 | Hypericin | Hypericine,Cyclosan | Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC |
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL... | |||
T2930 | α-Lipoic Acid | Lipoic acid,Alphalipoic acid | NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite |
α-Lipoic Acid (Alphalipoic acid) inhibits NF-κB-dependent HIV-1 LTR activation. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells.α-Lipoic Acid is an antioxidant, which is an es... | |||
T6761 | Ossirene | AS101 | IL Receptor , Caspase , Interleukin |
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme. | |||
T60627 | ELOVL1-IN-2 | Others | |
ELOVL1-IN-2, a compound known as an inhibitor of the elongation of very long chain fatty acid 1 (ELOVL1) enzyme, exhibits a weak inhibitory effect on ELOVL1 (with an IC50 of 21 μM) and demonstrates moderate potency in a ... |