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Search Results for " aspirin "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T0005	Aspirin	Acetylsalicylate,Acetylsalicylic Acid,ASA	Mitophagy , Virus Protease , COX , Autophagy
	Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...		Mitophagy , Virus Protease , COX , Autophagy
T68847	Aspirin calcium
	Aspirin calcium is the prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition...
T10391	Aspirin Aluminum	Aluminum diacetylsalicylate	Others
	Aspirin Aluminum is an intermolecular compound that can inhibit gastrointestinal mucosal disorders induced by NSAIDs.		Others
T20458	Aspirin DL-lysine	DL-Lysine acetylsalicylic acid salt,Aspegic,ASL,Aspisol
	Aspirin DL-lysine is a non-steroidal anti-inflammatory drug. It also may inhibit cancer growth. Aspirin DL-lysine is a water-soluble, injectable aspirin derivative.
T35946	17(R)-Resolvin D1	Aspirin-triggered Resolvin D1,17(R)-Resolvin D1
	Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.[1] In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response ...
T16328	Nitroaspirin	NCX 4016	Apoptosis , COX
	Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin induces significant induction of cell cycle arrest and apoptosis...		Apoptosis , COX
T0705	Triflusal	UR1501	COX , PDE , PPAR
	Triflusal (UR1501) is a 2-acetoxy-4-trifluoromethylbenzoic acid and it is an aspirin chemically-related molecule but not a derivative.		COX , PDE , PPAR
T19967	Fendosal	HP 129,P 71-0129,P71-0129,P-71-0129,HP129,HP-129	Immunology/Inflammation related
	Fendosal (HP-129) is a non-steroidal anti-inflammatory agent. It is 6.9 to 9.5 times more active than aspirin in the prophylactic and therapeutic adjuvant-induced polyarthritis models of chronic inflammation.		Immunology/Inflammation related
T22447	Tri-Salicylic Acid		Others
	Tri-Salicylic Acid, a product of the thermal decomposition of aspirin, is a compound for proteomics research.		Others
T39988	6'-GNTI dihydrochloride		Opioid Receptor , Akt
	6'-GNTI dihydrochloride is a κ-opioid receptor (KOR) agonist that favors activation of G-protein-mediated signaling over recruitment of β-aspirin 2. 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neur...		Opioid Receptor , Akt
T67924	ABzOH
	ABzOH is a benzoic acid derivative, similar in structure to non-steroidal anti-inflammatory drugs such as aspirin, with anti-inflammatory, anti-tumor and anti-proliferative effects. ABzOH can not only inhibit the express...
T69926	APHS
	APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.
T25576	KF 392	KF392,KF-392
	KF 392 is antiulcer. It was found that KF-392 given orally to rats at 1.0 to 5.0 mg/kg had a marked suppression on the developments of Shay ulcer as well as the aspirin-, stress-, and reserpine-induced gastric lesions.
T80635	Gentisuric acid		Drug Metabolite
	Gentisuric acid, an Aspirin metabolite and a substrate of α-amidating monooxygenase (PAM), mitigates DNA damage induced by Mitomycin C. [1] [2]		Drug Metabolite
T36042	17(R)-HDHA
	Resolvins are a group of polyhydroxylated metabolites of docosahexaenoic acid (DHA) found in the inflammatory exudates of aspirin-treated experimental animals. 17(R)-HDHA is the primary oxygenation product of DHA when ex...
T37633	17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
	17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2...
T37484	1-Salicylate Glucuronide
	1-Salicylate glucuronide is a metabolite of salicylic acid and aspirin .1It is formed from salicylic acid primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A9 but also by a variety of other UGT isoforms and ...
T37265	15(R)-Lipoxin A4	15(R)-Lipoxin A4,AT-Lipoxin A4
	Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspiri...
T36043	17(R)-Protectin D1	17(R)-Protectin D1
	17(R)-Protectin D1 is an aspirin-triggered epimer of the specialized pro-resolving mediator protectin D1 .1It decreases leukotriene B4-induced transendothelial migration of human polymorphonuclear (PMN) neutrophils when ...
T37490	11(R)-HETE
	11(R)-HETE is biosynthesized by 11(R)-LOs of the sea urchin, S. purpuratus, and the fresh water hydra, H. vulgaris. The biological activity of 11(R)-HETE relates to oocyte maturation and tentacle regeneration, respective...
T83599	(+)-Leucocyanidin	2,3-trans-3,4-trans-Leucocyanidin,(2R,3S,4R)-Leucocyanidin,3,4-trans-Leucocyanidin
	(+)-Leucocyanidin, an isoform of leucocyanidin and potent anti-ulcerogenic agent, has been extracted from Litchi chinensis. This compound exhibits considerable protective properties in rat models against aspirin-induced ...
T35431	(±)-Clopidogrel (hydrochloride)
	Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex ...
T37634	17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
	Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by asp...
T17231	Vicagrel		Others
	Vicagrel is an effective, orally active antiplatelet compound that enhances the inhibitory effect of aspirin on platelet aggregation and thrombosis in rodents by irreversibly inhibiting P2Y12 receptors and reducing metab...		Others
T35881	Resolvin E2
	Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-...
T37176	Edoxaban impurity 6
	Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaba...

Compounds

Aspirin

T0005

Synonym: Acetylsalicylate,Acetylsalicylic Acid,ASA

Target: Mitophagy, Virus Protease, COX, Autophagy

Synonym: Aluminum diacetylsalicylate

Target: Others

Aspirin DL-lysine

T20458

Synonym: DL-Lysine acetylsalicylic acid salt,Aspegic,ASL,Aspisol

Target:

17(R)-Resolvin D1

T35946

Synonym: Aspirin-triggered Resolvin D1,17(R)-Resolvin D1

Target: Apoptosis, COX

Triflusal

T0705

Synonym: UR1501

Target: COX, PDE, PPAR

Fendosal

T19967

Synonym: HP 129,P 71-0129,P71-0129,P-71-0129,HP129,HP-129

Target: Immunology/Inflammation related

6'-GNTI dihydrochloride

T39988

Synonym:

Target: Opioid Receptor, Akt

Synonym: KF392,KF-392

Target: Drug Metabolite

17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid

T37633

Synonym:

Target:

1-Salicylate Glucuronide

Synonym: 15(R)-Lipoxin A4,AT-Lipoxin A4

Target:

17(R)-Protectin D1

T36043

Synonym: 17(R)-Protectin D1

Synonym: 2,3-trans-3,4-trans-Leucocyanidin,(2R,3S,4R)-Leucocyanidin,3,4-trans-Leucocyanidin

Target:

(±)-Clopidogrel (hydrochloride)

T35431

Synonym:

Target:

17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

Cat No.	Product Name	Synonyms	Targets
T0004	Salicylamide	Salamide,2-Hydroxybenzamide	COX
	Salicylamide (2-Hydroxybenzamide) is an over-the-counter drug with analgesic and antipyretic properties, which has similar medicinal properties to aspirin. In the over-the-counter pain remedies, Salicylamide is used in c...		COX
T4810	Pyrocatechuic acid	3-Hydroxysalicylic acid,O-Pyrocatechuic acid,Catecholcarboxylic acid,NSC 27435,2,3-Dihydroxybenzoic acid	Others , Endogenous Metabolite
	Pyrocatechuic acid (Catecholcarboxylic acid), a normal human benzoic acid metabolite found in plasma, has increased levels after aspirin ingestion.		Others , Endogenous Metabolite
T5917	2-Hydroxy-6-methoxybenzoic acid	6-Methoxysalicylic acid	Others
	2-Hydroxy-6-methoxybenzoic acid (6-Methoxysalicylic acid) may be employed as internal standard for the determination of acetylsalicylic acid (aspirin, ASA) and its major metabolite, salicylic acid (SA),and exhibits signi...		Others
T4S21320	ISOGINKGETIN	4',4'''-Dimethylamentoflavone	MMP , Others
	1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponecti...		MMP , Others
T3S0509	Gaultherin		COX
	Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, w...		COX
TN4465	Luvangetin		COX , Prostaglandin Receptor , Antifection
	Luvangetin may have anti-inflammatory activity, it can inhibit NO and PGE2 production in LPS-stimulated BV2 cells. Luvangetin shows significant protection against pylorus-ligated and aspirin-induced gastric ulcers in rat...		COX , Prostaglandin Receptor , Antifection

Natural Products

Salicylamide

T0004

Synonym: Salamide,2-Hydroxybenzamide

Target: COX

Pyrocatechuic acid

T4810

Synonym: 3-Hydroxysalicylic acid,O-Pyrocatechuic acid,Catecholcarboxylic acid,NSC 27435,2,3-Dihydroxybenzoic acid

Target: Others, Endogenous Metabolite

2-Hydroxy-6-methoxybenzoic acid

T5917

Synonym: 6-Methoxysalicylic acid

Target: Others

ISOGINKGETIN

T4S21320

Synonym: 4',4'''-Dimethylamentoflavone

Target: COX, Prostaglandin Receptor, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02795	Eotaxin-2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in imm...

Eotaxin-2 Protein, Human, Recombinant (His)

TMPY-02795

Species: Human

Expression System: Baculovirus-Insect Cells

Cat No.	Product Name
L4710	Nonsteroidal Anti-Inflammatory Compound Library	530 compounds
	530 non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.
L4600	Selected Plant-Sourced Compound Library	3076 compounds
	A unique collection of 3076 plant-sourced compounds that derived from 277 plant species for high throughput screening (HTS) and high content screening (HCS);
L9410	Covalent Inhibitor Library	1949 compounds
	A unique collection of 1949 covalent Inhibitors and other molecules with common warheads like chloroacetyl，2-Chloropropionyl，Acryloyl，sulfonyl fluoride, alkyne，acrylamide, ketocarbonyl，disulfide bond, etc.

Libraries

Nonsteroidal Anti-Inflammatory Compound Library

L4710

Compounds: 530

Selected Plant-Sourced Compound Library

L4600

Compounds: 3076

Covalent Inhibitor Library

L9410

Compounds: 1949