Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin induces significant induction of cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells via down-regulation of EGFR/PI3K/STAT3 signaling and modulation of Bcl-2 family proteins. Nitroaspirin has antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 148.00 | |
2 mg | In stock | $ 222.00 | |
5 mg | In stock | $ 335.00 | |
10 mg | In stock | $ 455.00 | |
25 mg | In stock | $ 695.00 | |
50 mg | In stock | $ 857.00 | |
100 mg | In stock | $ 1,180.00 | |
200 mg | In stock | $ 1,590.00 | |
500 mg | In stock | $ 2,360.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 292.00 |
Description | Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin induces significant induction of cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells via down-regulation of EGFR/PI3K/STAT3 signaling and modulation of Bcl-2 family proteins. Nitroaspirin has antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1. |
Synonyms | NCX 4016 |
Molecular Weight | 331.28 |
Formula | C16H13NO7 |
CAS No. | 175033-36-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (166.02 mM)
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Nitroaspirin 175033-36-0 Apoptosis Immunology/Inflammation Neuroscience COX Inhibitor Cyclooxygenase NCX 4016 NCX4016 inhibit NCX-4016 inhibitor