Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponectin production. 2. Isoginkgetin has anti-tumor activity, the mechanistic basis is splicing inhibition , thus, pre-mRNA splicing inhibitors may represent a novel avenue for development of new anti-cancer agents.3. Isoginkgetin can inhibit tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression. 4. Isoginkgetin (0.3mg/kg ip for 3d) can reduce the level of O2·- in plasma and erythroeyte and sometimes increase the activity of SOD in anoxic rats, the action being stronger than aspirin.
Pack Size | Availability | Price/USD | Quantity |
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5 mg | In stock | $ 48.00 |
Description | 1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponectin production. 2. Isoginkgetin has anti-tumor activity, the mechanistic basis is splicing inhibition , thus, pre-mRNA splicing inhibitors may represent a novel avenue for development of new anti-cancer agents.3. Isoginkgetin can inhibit tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression. 4. Isoginkgetin (0.3mg/kg ip for 3d) can reduce the level of O2·- in plasma and erythroeyte and sometimes increase the activity of SOD in anoxic rats, the action being stronger than aspirin. |
Source |
Synonyms | 4',4'''-Dimethylamentoflavone |
Molecular Weight | 566.51 |
Formula | C32H22O10 |
CAS No. | 548-19-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 83.3 mg/mL (147.04 mM)
You can also refer to dose conversion for different animals. More
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ISOGINKGETIN 548-19-6 Others Proteases/Proteasome MMP inhibit NF-κB Matrix metalloproteinases Inhibitor HeLa HT1080 Proteasome Nuclear factor-κB Autophagy Nuclear factor-kappaB Apoptosis Protein kinase B 4',4'''-Dimethylamentoflavone Akt anticancer PKB inhibitor