app — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T30103	APP-CHMINACA	PX-3,PX3
	APP-CHMINACA is a synthetic cannabinoid (CB) featuring a 1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (CHMINACA) base. It displays a 10-fold greater affinity for the central CB1 receptor than that of JWH 018.
T21890	JLK6		Gamma-secretase
	JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signalling		Gamma-secretase
T9713	δ-secretase inhibitor 11		Beta Amyloid , Caspase
	δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.		Beta Amyloid , Caspase
T32570	Lappaconine	20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol,O(sup 1)-Methyllappaconidine	Others
	Lappaconine (20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol) derivated from norditerpenoid alkaloids.		Others
T6S1780	Protosappanin B	Q-100961,FT-0689654	Apoptosis
	1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, vi...		Apoptosis
T38570	DMAPP triammonium	Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt	Others
	DMAPP triammonium (Dimethylallyl diphosphate triammonium) is one of the prerequisite substances for an isoprenoid involved in the mevalonate (MVA) pathway, which can be used in the study of metabolism-related diseases.		Others
T2806	Lappaconitine	(+)-Lappaconitine	P2X Receptor , Sodium Channel
	Lappaconitine ((+)-Lappaconitine), isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.		P2X Receptor , Sodium Channel
T13589	Caesappanin C		Others
	Caesappanin C, extracted from the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro.		Others
T78337	Mouse IgG2a kappa, Isotype Control
	Mouse IgG2a kappa, Isotype Control is an isotype antibody to murine-derived IIgG2a kappa antibody.
TJS1779	Protosappanin A	PTA	NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
	Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IÎºB/NF-ÎºB inflammation signal pathway; it exerts anti-neuroinflammatory ...
T6560	Lappaconitine hydrobromide	Lappaconite HBr,Allapinine	Others
	Lappaconitine hydrobromide (Allapinine) is a kind of alkaloid extracted from Aconitum sinomontanum Nakai. It has anti-inflammatory effects.		Others
TP1798	Pep-1 (uncapped)	Pep-1 uncapped	Others
	Pep-1 (uncapped), which has 21 amino acid residues, is a known carrier peptide that delivers full-length native proteins in vitro and in vivo.		Others
TMA1570	Sappanone A		NF-κB , Nrf2
	Sappanone A is a high isoflavanone that exhibits anti-inflammatory effects by modulating Nrf2.Sappanone A attenuates allergic airway inflammation in ovalbumin-induced asthma.		NF-κB , Nrf2
T125353	Apparicine
	Apparicine is a useful organic compound for research related to life sciences and the catalog number is T125353.
T126471	3'-Deoxy-4-O-methylepisappanol
	3'-Deoxy-4-O-methylepisappanol is a useful organic compound for research related to life sciences and the catalog number is T126471.
T36760	KQMEEEAVRLFIEWLKNGGPSSGAPPPS
	KQMEEEAVRLFIEWLKNGGPSSGAPPPS is a Exendin-4 peptide derivative. Exendin-4 is a pure GLP-1 receptor agonist. Exendin-4 peptide derivatives are structurally derived from Exendin-4 and may relates to dual GLP-1/glucagon rec...
TN4410	Lappaol C		P-gp , JNK
	Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidat...		P-gp , JNK
T40454	DMAPP	Dimethylallyl diphosphate
	DMAPP, also known as Dimethylallyl pyrophosphate, is an isoprenoid precursor found in all life forms. It serves as an isomer of isopentenyl pyrophosphate (IPP).
T73416	BiCAPPA
	BiCAPPA, a pioneering bivalent antiprion ligand, effectively reduces the infectious conformational form of prion protein (PrP Sc) in scrapie-infected cells, achieving this at a concentration (EC 50) of 0.32 μM.
T76028	Amylin (IAPP), feline TFA
	Amylin (IAPP), feline TFA, a 37-amino acid polypeptide derived from felines, stands as a principal secretion product of the pancreatic islets' β-cells. This regulatory peptide notably inhibits the secretion of insulin an...