Powder: -20°C for 3 years | In solvent: -80°C for 1 year
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3-O-Methylgallic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 30.00 | |
500 mg | In stock | $ 64.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | 3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. 3-O-Methylgallic acid inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1 which are known to be activated in colorectal cancer. |
Targets&IC50 | cell proliferation:24.1 μM(Caco-2 cells) |
In vitro | 3,4-Dihydroxy-5-methoxybenzoic acid(10-100 μM) caused a time- and dose-dependent decrease in cell viability[1]. |
Source |
Synonyms | 3,4-Dihydroxy-5-methoxybenzoic acid |
Molecular Weight | 184.15 |
Formula | C8H8O5 |
CAS No. | 3934-84-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 37.5 mg/mL (203.64 mM)
You can also refer to dose conversion for different animals. More
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3-O-Methylgallic acid 3934-84-7 Apoptosis Cell Cycle/Checkpoint DNA Damage/DNA Repair JAK/STAT signaling Membrane transporter/Ion channel NF-Κb Stem Cells NF-κB STAT OCT DNA/RNA Synthesis 3,4-Dihydroxy-5-methoxybenzoic acid Anthocyanin 3 O Methylgallic acid inhibit 3OMethylgallic acid metabolite anti-cancer Inhibitor anti-proliferation antioxidant inhibitor