variant — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T81589	OVA-A2 Peptide	SAINFEKL, OVA (257-264) Variant
	OVA-A2 Peptide (SAINFEKL, OVA (257-264) Variant) is a biologically active, antigenic variant of the ovalbumin-derived peptide spanning amino acids 257 to 264.
T83852	EGFRvIII Peptide TFA	PEGFRvIII (9-mer),Epidermal Growth Factor Receptor Variant III Peptide
	EGFRvIII peptide, a synthetic peptide mirroring the EGFRvIII fusion junction—a tumor-specific, perpetually active EGFR variant missing amino acids 6-273 of the wild-type—binds to HLA-A*0201-positive T2 cells under MHC cl...
T7904	SR 19881		Estrogen/progestogen Receptor
	SR 19881 is a full agonist of ERRγ(EC50 value of 0.39 μM in a binding assay and an EC50 value of 4.7 μM in a cell-based assay).		Estrogen/progestogen Receptor
T9716	Ensitrelvir	S-217622	SARS-CoV
	Ensitrelvir (S-217622) is an orally active inhibitor of SARS-CoV-2 3CL protease with IC50 of 13 nM.		SARS-CoV
T8083	Pyridoxal 5'-phosphate monohydrate	Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate	Others
	Pyridoxal 5'-phosphate monohydrate is an active vitamin B6 metabolite		Others
T7905	PBD-150		Beta Amyloid
	PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)		Beta Amyloid
T64221	Linvencorvir	RG7907	HBV , Antibiotic
	Linvencorvir is a hepatitis B virus (HBV) core protein variant modifier used to treat chronic HBV infection.		HBV , Antibiotic
T40279	GLP-1R modulator L7-028	GLP-1R modulator L7-028	cAMP , Glucagon Receptor
	GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.		cAMP , Glucagon Receptor
T77407	Ensituximab	NPC-1C,NEO-102,NEO-101
	Ensituximab (NEO-102) is a quasi-selective IgG1 monoclonal antibody against the MUC5AC variant with anti-tumour activity that inhibits colorectal and pancreatic cancer.
T4220	BQR-695	BQR695,NVP-BQR695	PI3K , Parasite , PI4K
	BQR-695 (NVP-BQR695) is a phosphatidylinositol 4-kinase (PI4K) inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively.		PI3K , Parasite , PI4K
T11421	Glutaminase-IN-1	CB839 derivative	transporter
	Glutaminase-IN-1 (CB839 derivative), a novel 1,3,4-selenodiazepine renal-type glutaminase (KGA) variant inhibitor, showed antitumor activity in an aggressive H22 hepatocellular carcinoma xenograft model.		transporter
T61191	EAI001		EGFR
	EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.EAI001 can be used in cancer research.		EGFR
T1952	MK-2206 dihydrochloride	MK-2206 2HCl	Apoptosis , Akt , Autophagy
	MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor a...		Apoptosis , Akt , Autophagy
T64387	2-Nitrobenzoic acid	o-Nitrobenzoic acid	Others
	2-Nitrobenzoic acid (o-Nitrobenzoic acid) is a antiproliferation agent. 2-Nitrobenzoic acid shows IC50 of 8.3 μM to jurkat cell line expressing T type calcium channel alpha 1H or its splice variant delta 25.		Others
T26863	BMS-929075	BMS 929075,BMS929075	HCV Protease
	BMS-929075 is an orally active HCV NS5B replicase (HCV NS5B replicase) palm site variant inhibitor with potency, high oral bioavailability and pharmacokinetic parameters.BMS-929075 shows cytotoxicity.		HCV Protease
T82236	HBED-CC-tris(tert-butyl ester)		Others
	HBED-CC-tris(tert-butyl ester) is a monovalent variant of HBED-CC that can be used in the synthesis of synthetic radiocompounds based on asymmetric HBED-CC that can be used for tumor imaging.		Others
T4757	L-Homoserine	(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID	Others , Endogenous Metabolite
	L-Homoserine ((S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID) is a more reactive variant of the amino acid serine. In this variant, the hydroxyl side chain contains an additional CH2 group which brings the hydroxyl group closer t...		Others , Endogenous Metabolite
TP1591L	OVA G4 peptide acetate(148274-82-2 free base)	SIIGFEKL acetate	Others
	OVA G4 peptide acetate(148274-82-2 free base) (SIIGFEKL acetate) is a variant of the agonist ovalbumin (OVA) peptide (257-264), SIINFEKL. OVA Peptide is a class I (Kb)-restricted peptide epitope of ovalbumin presented by...		Others
T60835	SKF83959		Dopamine Receptor
	SKF83959, a benzazepine analog, is a selective and potent partial agonist of the dopamine D1 receptor with Ki values of 1.18, 7.56, 920, and 399 nM for rat D1, D5, D2, and D3 receptors, respectively.SKF83959 is a potent ...		Dopamine Receptor
T10534	BI-4020		EGFR
	BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase. BI-4020 exhibits activity agains the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines), the d...		EGFR