Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ensitrelvir (S-217622) is an orally active inhibitor of SARS-CoV-2 3CL protease with IC50 of 13 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 50.00 | |
25 mg | In stock | $ 115.00 |
Description | Ensitrelvir (S-217622) is an orally active inhibitor of SARS-CoV-2 3CL protease with IC50 of 13 nM. |
Targets&IC50 | 3CLpro (SARS CoV-2):13 nM |
In vitro | The EC50 values for SARS-CoV and MERS-CoV were 0.21 and 1.4 μM respectively. In a cytopathic effect (cpe)-inhibition assay of SARS-CoV-2 infected VeroE6/TMPRSS2 cells, Ensitrelvir shows the EC50 values are approximately 0.4 μM for both wild-type virus and Alpha, Beta, Gamma and Delta variants[1]. |
In vivo | Ensitrelvir inhibits intrapulmonary replication of SARS-CoV-2 in mice in a dose-dependent manner[1]. |
Synonyms | S-217622 |
Molecular Weight | 531.88 |
Formula | C22H17ClF3N9O2 |
CAS No. | 2647530-73-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 160 mg/mL (300.82 mM)
You can also refer to dose conversion for different animals. More
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Ensitrelvir 2647530-73-0 Microbiology/Virology SARS-CoV intrapulmonary replication Virus Protease COVID-19 oral SARS coronavirus S-217622 variant Inhibitor S 217622 inhibit S217622 inhibitor