sterol — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4039	BIBB 515		Others
	BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of...		Others
T20237	Fenhexamid	Elevate,Teldor	Antifungal
	Fenhexamid (Elevate), a sterol biosynthesis inhibitor, shows antifungal activity against the plant pathogenic fungus. Fenhexamid is used for agriculture and is present in measurable amounts in fruits and vegetables.		Antifungal
T20691	Fenpropidin	Ro12-3049,Ro-12-3049,Ro 12-3049	Antifungal
	Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.		Antifungal
T70931	SYK-IN-II
	SYK-IN-II is an inhibitor of the spleen tyrosine kinase (STK).
TN6736	Dihydrolanosterol	24,25-Dihydrolanosterol,Lanostenol	Others
	Dihydrolanosterol (24,25-Dihydrolanosterol) is a sterol and the C24-25 hydrogenated products of lanosterol, dihydrolanosterol can be demethylated by mammal or yeast cytochrome P450 sterol 14alpha-demethylase		Others
T4S2157	Campesterol	(24R)-5-Ergosten-3β-ol	Endogenous Metabolite
	Campesterol ((24R)-5-Ergosten-3β-ol) is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory e...		Endogenous Metabolite
T41008	BODIPY-Cholesterol	BCh2
	BODIPY-Cholesterol (TF-Chol) is a cholesterol analog with a fluorescent BODIPY motif and cellular permeability, and is a novel BODIPY cholesterol probe.BODIPY-Cholesterol can be used to study intracellular sterol uptake ...
T0760	Cholesterol	Cholesterin,Cholesteryl alcohol	Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
	Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is widely found in the cell membranes of animals and is also us...		Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
T4717	25-Hydroxycholesterol		Others , Endogenous Metabolite , HMG-CoA Reductase
	25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regu...		Others , Endogenous Metabolite , HMG-CoA Reductase
T35973	Cholesterol-5α,6α-epoxide	Epoxycholesterol,5α,6α-epoxy Cholestanol,NSC 18176	Others
	Cholesterol-5α,6α-epoxide (Epoxycholesterol) is the metabolite of cholesterol produced by oxidation. Cholesterol-5α,6α-epoxide induces triacylglycerol biosynthesis by binding to LXRβ following tamoxifen and PBPE applicat...		Others
T3770	Taraxasterol	Taraxasterin	IL Receptor , TNF , NO Synthase , Prostaglandin Receptor
	Taraxasterol (Taraxasterin) is compound with anti-inflammatory activity.		IL Receptor , TNF , NO Synthase , Prostaglandin Receptor
T60796	Cholesterol 24-hydroxylase-IN-1
	Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1) with IC50 of 8.5 nM that can cross blood-brain barrier [1].
T10085	20(S)-Hydroxycholesterol	20α-Hydroxycholesterol	Smo
	20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo).		Smo
T15720	Lathosterol		Endogenous Metabolite
	Lathosterol, a molecule akin to cholesterol, serves as a biomarker for the body's total cholesterol synthesis, as indicated by its serum concentration.		Endogenous Metabolite
TN7127	5,6-Epoxyergosterol		Others
	5,6-Epoxyergosterol is derived from the endophytic fungus Phyllosticta capitalensis.		Others
TN7071	Ergosterol Acetate	Ergosta-5,7,22-trien-3-beta-yl acetate	Others
	Ergosterol Acetate (Ergosta-5,7,22-trien-3-beta-yl acetate) is one of the acetate derivatives of Ergosterol from Monascus anka.		Others
T10086	24-Hydroxycholesterol	Cholest-5-ene-3beta,24-diol	Liver X Receptor , NMDAR
	24-Hydroxycholesterol (Cholest-5-ene-3beta,24-diol) is an oxysterol compound that is an activator of the n-methyl-d-aspartate receptor (NMDA) and the transcription factor LXR, which has been used in the study of cardioge...		Liver X Receptor , NMDAR
T8040	Cholesterol myristate	Cholesteryl myristate,Cholesteryl tetradecanoate	Others , Potassium Channel , GABA Receptor , Endogenous Metabolite , AChR
	Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the GABAA receptor, nicotinic acetylcholine receptor, and the i...
TQ0274	27-Hydroxycholesterol	25(R)-27-hydroxy Cholesterol	Estrogen/progestogen Receptor , Liver X Receptor
	27-Hydroxycholesterol (25(R)-27-hydroxy Cholesterol) is a selective modulator of estrogen receptor and an agonist of the liver X receptor.		Estrogen/progestogen Receptor , Liver X Receptor
T19711	Desmosterol	Desmesterol,24-Dehydrocholesterol	Endogenous Metabolite
	Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation and prevents vascular inflammation and atherosclerosis.		Endogenous Metabolite