specific — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T41255	Specific PXR antagonist 70		Others
	Specific PXR antagonist 70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM for human PCR and enhances the chemosensitivity of cancer cells.		Others
T36104	Citrulline-specific Probe-Rhodamine
	Protein arginine deiminases (PADs) catalyze the posttranslational modification of arginine residues on proteins to form citrulline, which plays a large role in regulating gene expression. Abnormally high PAD activity has...
T7347	CU-CPT-8m	TLR8-specific antagonist	TLR
	CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)		TLR
T23486	Ubiquitin specific protease 3 fragment		Others
	The ubiquitin speci c protease 3 USP3 is a deubiquitinating enzyme for uH2A and uH2B.		Others
T36627	Lysine-specific Demethylase Inhibitor (1C) (hydrochloride)
	Lysine-specific demethylase inhibitor (1C) (LSD inhibitor (1C)) is an inhibitor of LSD1, a repressive demethylase selective for histone H3 lysine 4 (H3K4).1,2LSD inhibitor (1C) inhibits LSD1 activity by 85.9% when used a...
T7302	CU-CPT9b	CU-CPT-9b,TLR8-specific antagonist 1	TLR
	CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 valu...		TLR
T80552	Prostate Specific Antigen Substrate
	Prostate Specific Antigen Substrate is a fluorescent substrate specific to prostate specific antigen (PSA) and facilitates the detection of PSA enzymatic activity [1].
T82387	Fluorescent Substrate for Asp-Specific Proteases
	Fluorescent Substrate for Asp-Specific Proteases selectively cleaves the Asp-Val bond [1].
T82386	Fluorescent Substrate for Glu-Specific Proteases
	Fluorescent Substrate for Glu-Specific Proteases is a chromogenic substrate specifically recognized by V8 protease [1].
T23351	Shz 1		Others
	induces phenotypic differentiation		Others
T22795	Gadolinium chloride		CaSR
	Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist		CaSR
T9202	DDO-5936		HSP
	DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.		HSP
T24109	GSK329	GSK 329,GSK-329	Others
	GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.		Others
T26324	VU0071063	VU 0071063,VU-0071063	Potassium Channel
	VU0071063 is a Kir6.2/SUR1 activator.		Potassium Channel
T6052	GW 441756		Apoptosis , Raf , Trk receptor , CDK
	GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.		Apoptosis , Raf , Trk receptor , CDK
T27719	KD-026	SLx 4090,SLx4090,KD026,SLx-4090	CETP
	KD-026 (SLx 4090), a microsomal triglyceride transfer protein (MTP) inhibitor(IC50 = 8.0 nM), is used in type 2 diabetes studies.		CETP
T15017	CU-T12-9		TLR
	CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activat...		TLR
T41302	Itaconate-alkyne	ITalk	Others
	Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its dire...		Others
T7008	Vacquinol-1	Vacquinol 1	JNK
	Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.		JNK
T7123	AMG-47a		VEGFR , p38 MAPK , JAK , Src
	AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei...		VEGFR , p38 MAPK , JAK , Src