Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
2 mg | In stock | $ 74.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 197.00 | |
25 mg | In stock | $ 369.00 | |
50 mg | In stock | $ 558.00 | |
100 mg | In stock | $ 788.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 133.00 |
Description | CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM. |
Targets&IC50 | TLR8:0.7 nM (IC50), TLR8:21 nM (Kd) |
Synonyms | CU-CPT-9b, TLR8-specific antagonist 1 |
Molecular Weight | 251.28 |
Formula | C16H13NO2 |
CAS No. | 2162962-69-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (397.96 mM)
You can also refer to dose conversion for different animals. More
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CU-CPT9b 2162962-69-6 Immunology/Inflammation TLR inhibit Toll-like Receptor (TLR) Inhibitor CU-CPT-9b CUCPT9b CU CPT9b TLR8-specific antagonist 1 inhibitor