Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

CU-CPT-8m

🥰Excellent
Catalog No. T7347Cas No. 125079-83-6
Alias TLR8-specific antagonist

CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)

CU-CPT-8m

CU-CPT-8m

🥰Excellent
Purity: 99.00%
Catalog No. T7347Alias TLR8-specific antagonistCas No. 125079-83-6
CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$32In StockIn Stock
5 mg$48In StockIn Stock
10 mg$77In StockIn Stock
25 mg$141In StockIn Stock
50 mg$221In StockIn Stock
100 mg$333-In Stock
1 mL x 10 mM (in DMSO)$65In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.00%
Contact us for more batch information

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity
Description
CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)
Targets&IC50
TLR8:67 nM
In vivo
CU-CPT8m decreases TNF-α and IL-8 levels in synovial cells derived from patients with osteoarthritis and TNF-α levels in PBMCs derived from patients with rheumatoid arthritis.
SynonymsTLR8-specific antagonist
Chemical Properties
Molecular Weight252.27
FormulaC14H12N4O
Cas No.125079-83-6
SmilesCc1cccc(c1)-c1ccnc2c(cnn12)C(N)=O
Relative Density.1.35 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30 mg/mL (118.92 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9640 mL19.8200 mL39.6401 mL198.2003 mL
5 mM0.7928 mL3.9640 mL7.9280 mL39.6401 mL
10 mM0.3964 mL1.9820 mL3.9640 mL19.8200 mL
20 mM0.1982 mL0.9910 mL1.9820 mL9.9100 mL
50 mM0.0793 mL0.3964 mL0.7928 mL3.9640 mL
100 mM0.0396 mL0.1982 mL0.3964 mL1.9820 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Toll-like Receptor (TLR)TLR8TLRInhibitorinhibitCU-CPT-8mCUCPT8mCU CPT 8m
Related Tags: buy CU-CPT-8m | purchase CU-CPT-8m | CU-CPT-8m cost | order CU-CPT-8m | CU-CPT-8m chemical structure | CU-CPT-8m in vivo | CU-CPT-8m formula | CU-CPT-8m molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.