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MAPK Raf GW 441756

GW 441756

Catalog No. T6052   CAS 504433-23-2

GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.

GW 441756, CAS 504433-23-2
Pack Size Availability Price/USD Quantity
5 mg In stock 78.00
10 mg In stock 102.00
25 mg In stock 249.00
50 mg In stock 458.00
100 mg In stock 595.00
1 mL * 10 mM (in DMSO) In stock 112.00
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Purity 99.80%
Purity 98.43%
Purity 98.00%
Biological Description
Chemical Properties
Storage & Solubility Information
Description GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.
Targets&IC50 CDK2 ,   C-Raf-1 ,   TrkA
Molecular Weight 275.3
Formula C17H13N3O
CAS No. 504433-23-2

Storage

0-4℃ for short term (days to weeks), or -20℃ for long term (months).

Solubility Information

DMSO: 4.1 mg/mL (15 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Wood ER, et al. Bioorg Med Chem Lett, 2004, 14(4), 953-957. 2. Eun Joo Jung, et al. Exp Mol Med, 2008, 40(3), 276–285. 3. Jung EJ, et al. Mol Cells, 2008, 26(1), 12-17.

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compound Library Inhibitor Library Anti-cancer Compound Library Apoptosis Compound Library MAPK Inhibitor Library Tyrosine kinase inhibitor library Kinase Inhibitor Library Anti-Cardiovascular Disease Compound Library Cell cycle related Compound Library Anti-obesity Compound Library HIF-1 Signaling Pathway Compound Library Anti-Lung Cancer Compound Library Covalent Inhibitor Library Anti-Breast Cancer Compound Library Anti-Pancreatic Cancer Compound Library

Related Products

Related compounds with same targets
Milciclib Furanodiene Sodium Oxamate THAL-SNS-032 A-674563 2HCl(552325-73-2(fb-2hcl)) I-49 free base I-37 free base( 2359690-13-2(free base)) BMS265246

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Answers to questions you may have can be found in the Inhibitor Handling Instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.