solubility — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3978	Linerixibat	GSK2330672,Iinerixibat	HBV
	Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.		HBV
T20597	Alginic acid	Protanal LF,Snow acid algin G,Kelacid,Sazzio,Norgine	Apoptosis , Autophagy , Histamine Receptor
	Alginic acid (Snow acid algin G) is a natural polysaccharide extracted from brown seaweeds with anti-anaphylactic and anti-inflammatory activities. Alginic acid inhibits histamine release and can be used in the food indu...		Apoptosis , Autophagy , Histamine Receptor
T24493	Monoelaidin
	Monoelaidin is a poorly water-soluble drug enhancer of solubility and oral bioavailability.
T20331	Sodium lauroyl glutamate	Hostapon CLG,Amisoft LS 11,Sodium N-lauroylglutamate,Acylglutamate LS-11	Others
	Sodium lauroyl glutamate (Acylglutamate LS-11) is an amino acid detergent and increases the solubility of long-chain alkyl gallates such as alkyl gallates.		Others
T20075	Sodium dodecyl sulfate	Laurylsulfuric acid sodium salt,NSC 402488,Anticerumen,NSC-402488,NSC402488,Natrium laurylsulfuricum,Sodium dodecylsulfate,Sodium lauryl sulfate	Others
	Sodium dodecyl sulfate(Sodium lauryl sulfate) is a pharmaceutical excipient that is biologically inactive and improves the stability, solubility and processability of pharmaceutical preparations.		Others
T8238	Fosamprenavir Calcium Salt	Diallyl Trisulfide,GW433908G	HIV Protease
	Fosamprenavir Calcium Salt (GW433908G) (GW433908G) is a phosphate ester prodrug of the antiretroviral protease inhibitor Amprenavir, with improved solubility. Fosamprenavir Calcium Salt has Anti-HIV infection.		HIV Protease
T2P2898	Neodiosmin	Diosmetin-7-neohesperidoside,Diosmetin-7-O-neohesperidoside	Antioxidant
	1. Neodiosmin (Diosmetin-7-O-neohesperidoside) has poor aqueous solubility but exerts a good debittering effect and is a strong antioxidant with potential applications in foods, beverages, and pharmaceutical preparations...		Antioxidant
T4545	Propacetamol Hydrochloride	Propacetamol HCL	Others
	Propacetamol Hydrochloride (Propacetamol HCL) is a prodrug of paracetamol (acetaminophen) with improved water solubility. Propacetamol Hydrochloride is an analgesic drug delivered by IV when the oral application of NSAID...		Others
T24047	Etilevodopa hydrochloride	Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester	Others , Dopamine Receptor , Drug Metabolite
	Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration.		Others , Dopamine Receptor , Drug Metabolite
T5749	10-Deacetyl-7-xylosyl paclitaxel	10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,10-Deacetylpaclitaxel 7-Xyloside	Others , Microtubule Associated
	10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used in Chinese clinics to treat cancer.		Others , Microtubule Associated
T13947	Tween 80		Others
	Tween 80 is a nonionic surfactant and emulsifier that reduces bacterial adherence and inhibits biofilm formation. Tween 80 is widely used as a co-solvent in pharmacology experiments because of its ability to enhance the ...		Others
TP1809	TAT		HIV Protease
	TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and production of heterologous proteins[1]. This cell-penetrating pept...		HIV Protease
T5593	L-Alanyl-L-glutamine	Ala-Gln	Others , Endogenous Metabolite
	L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln).		Others , Endogenous Metabolite
T50013	4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzoic acid		Others
	4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzoic acid is a synthetic compound with potent antitumor activity, high efficiency and selectivity against tumor cells. However, it has poor solubility in water and is pot...		Others
TN2111	Prunin	Naringenin 7-0-glucoside	Phosphatase , Anti-infection , Virus Protease
	Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can...		Phosphatase , Anti-infection , Virus Protease
T8947	Dasiglucagon acetate	dasiglucagon acetate(1544300-84-6 free base)	Others
	Dasiglucagon acetate is a novel glucagon analog for diabetic hypoglycemia therapy. Dasiglucagon acetate has demonstrated established solubility and stability in an aqueous formulation. Pharmacokinetics studies have shown...		Others
T14050	5-FAM	5-Carboxyfluorescein	Others
	5-FAM (5-Carboxyfluorescein) (5-Carboxyfluorescein) contains a carboxylic acid, which can be used to react with primary amines via carbodiimide activation of the carboxylic acid. Fluorescein is the most common fluorescen...		Others
T14589	Biotin-PEG3-acid		Others , PROTAC Linker
	Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophil...		Others , PROTAC Linker
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T68426	Dipfluzine
	Dipfluzine is a diphenylpiperazine calcium channel blocker with poor solubility.