radical — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T82372	Free radical scavenger 1
	Compound 8, a free radical scavenger, exhibits an IC50 value of 43.39 μg/ml in neutralizing the DPPH radical [1].
TN1873	Lirinidine		Others
	(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a...		Others
T9057	Norbergenin		IL Receptor , TNF , Reactive Oxygen Species
	Norbergenin is a chemical compound. It is the O-demethylated derivative of bergenin. It can be isolated from rhizomes of Bergenia stracheyi.		IL Receptor , TNF , Reactive Oxygen Species
TN1058	Pelargonidin chloride		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
	Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway.		NOS , Reactive Oxygen Species , Nrf2 , NO Synthase
T6S1440	Loganic acid	Loganate	Others
	1. Loganic acid (Loganate) and geniposide exhibit both sides effect on superoxide generation.		Others
TN1621	Eriodictyol-7-O-glucoside		Nrf2
	Eriodictyol-7-O-glucoside is an Nrf2 activator conferring protection against Cisplatin-induced toxicity. Eriodictyol-7-O-glucoside is a flavonoid and a free radical scavenger with antioxidant activity in pistachio skin.		Nrf2
T9135	Epirosmanol		Others
	Epirosmanol is a diterpenoid containing a lactone moiety. Epirosmanol is a very weakly basic (essentially neutral) compound (based on its pKa).		Others
T2S1181	Aloenin	Aloenin A,Aloearbonaside	Beta-Secretase , AChR
	1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro.		Beta-Secretase , AChR
T41358	2-Hydroxybenzylamine		Others
	2-Hydroxybenzylamine, a potent small molecule scavenger of IsoLGs, sequesters the reactive species as inert adducts. 2-Hydroxybenzylamine may be used to decrease early recurrence of atrial fibrillation and other atrial a...		Others
T8794	4-MMPB	15-Lipoxygenase Inhibitor 1	Apoptosis , Others , Lipoxygenase
	15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxyg...		Apoptosis , Others , Lipoxygenase
T22308	Dimboa	2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one	Others , Antibacterial , Antibiotic , Antifungal
	Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal compound used in crops.		Others , Antibacterial , Antibiotic , Antifungal
T7717	Sodium 2-oxopropanoate	Sodium pyruvate	Reactive Oxygen Species , Endogenous Metabolite
	Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease.		Reactive Oxygen Species , Endogenous Metabolite
TN6706	3-demethylcolchicine		Reactive Oxygen Species
	3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin.		Reactive Oxygen Species
T5363	Tempo	2,2,6,6-Tetramethylpiperidinooxy	Free radical scavengers , Reactive Oxygen Species , DNA/RNA Synthesis , Mitochondrial Metabolism
	Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.
TN2011	Ombuoside	Ombuin-3beta-rutinoside	Antibacterial
	Ombuoside (Ombuin-3beta-rutinoside) has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma penta...		Antibacterial
T5678	Lazabemide hydrochloride	N-(2-Aminoethyl)-5-chlor-2-pyridincarbox	MAO , Monoamine Oxidase
	Lazabemide hydrochloride (N-(2-Aminoethyl)-5-chlor-2-pyridincarbox) is a reversible and selective mao-b inhibitor(Ki：7.9nM).		MAO , Monoamine Oxidase
TN2165	Rubrofusarin gentiobioside	Rubrofusarin-6-O-beta-D-gentiobioside	ERK , NF-κB , TGF-beta/Smad
	Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) can significantly decrease the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity, suggests that it has potential as a preventive...		ERK , NF-κB , TGF-beta/Smad
T21233	Dihydrolipoic acid	Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid	Antioxidant
	Dihydrolipoic acid (USAF XR-12), a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydr...		Antioxidant
T37710	5-Hydroxyoxindole		Reactive Oxygen Species
	5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit...		Reactive Oxygen Species
TN6909	Polyporusterone B	(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one	Others
	Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) is a triterpene carboxylic aci...		Others