parasites — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN6730	Epoxyazadiradione		NF-κB
	Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells.		NF-κB
T4188	SDZ285428	SDZ285-428	P450 , Parasite , Antifungal
	SDZ285428 is a CYP24A1 inhibitor.		P450 , Parasite , Antifungal
T0849	Pyrimethamine	Pirimecidan,RP 4753,Pirimetamin	DHFR , Antifolate , Parasite
	Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.		DHFR , Antifolate , Parasite
T2279	Tizoxanide	Desacetyl-nitazoxanide,TIZ	Antiviral , HIV Protease , Antibacterial , Autophagy
	Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).		Antiviral , HIV Protease , Antibacterial , Autophagy
T15173	DSM265	PfSPZ	Dehydrogenase , Parasite
	DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity (IC50: 8.9 nM).DSM265 inhibits the growth of Pf3D7 parasites and can be used for the treatment and prophylaxis of malaria infectio...		Dehydrogenase , Parasite
T0390	Aklomide	Alkomide,2-Chloro-4-nitrobenzamide	Antibiotic , Parasite
	Aklomide (2-Chloro-4-nitrobenzamide) is used in poultry to treat parasites.		Antibiotic , Parasite
T1061	Toltrazuril	BAY-i 9142,Toltrazurilo,Baycox,Toltrazurilum	Antibiotic , Parasite
	Toltrazuril (Toltrazurilo), an antiprotozoal agent, has effect on Coccidia parasites.		Antibiotic , Parasite
T7744	Piperaquine tetraphosphate tetrahydrate		Parasite
	Piperaquine tetraphosphate tetrahydrate is a potent anti-parasites agent.		Parasite
T20812	Azamethiphos		AChE
	Azamethiphos, an organothiophosphate insecticide, is used in Atlantic salmon fish farming to control parasites.		AChE
T13539	Allopurinol riboside		Others , Endogenous Metabolite , Parasite , Drug Metabolite
	Allopurinol riboside is a metabolite of allopurinol with potency against parasites. Allopurinol riboside competitively inhibits the action of purine nucleoside phosphorylase on inosine with a Ki of 277 μM.		Others , Endogenous Metabolite , Parasite , Drug Metabolite
T37072	Nitroxynil	4-Hydroxy-3-iodo-5-nitrobenzonitrile,Trodax,Dovenix	Parasite
	Nitroxynil (4-Hydroxy-3-iodo-5-nitrobenzonitrile) is an anthelmintic compound that effectively targets parasites in both adult and immature stages. It is extensively employed in investigations pertaining to Fasciola hepa...		Parasite
T6607	Nitenpyram	Niterndipoine,Bestguard,Capstar	AChR
	Nitenpyram (Capstar) is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.		AChR
T5052	Toltrazuril (sulfone)	Toltrazuril sulfone,Ponazuril	Parasite
	Toltrazuril sulfone (Ponazuril) is an antiprotozoal agent that acts upon Coccidia parasites.		Parasite
T3361	Cambendazole	Bonlam,MK-905,Novazole	Others
	Cambendazole (Novazole) is one of the most effective agents for the therapy of human strongyloidiasis. Cambendazole is a nematocide effective against a variety of gastrointestinal parasites in cattle, sheep, and horses.		Others
T0951	Hydroxychloroquine sulfate	Acidum iopanoicum,HCQ sulfate	DNA , SARS-CoV , TLR , Parasite , Autophagy
	Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in ...		DNA , SARS-CoV , TLR , Parasite , Autophagy
T28824	SNX0723	SNX 0723,SNX- 0723	HSP
	SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respectively. SNX0723 inhibits liver-stage P. berghei ANKA parasit...		HSP
T9549	Chiniofon	Loretin,Ferron,8-hydroxy-7-iodo-5-quinolinesulfonate,quiniophen	Others
	Chiniofon (Ferron), a halogenated 8-hydroxyquinoline, is used as an antiamebic drug. This type of anti-amebic drug exerts an anti-amebic effect by inhibiting intestinal commensal bacteria and affects amoebic dysentery, b...		Others
TN4883	Quinine sulfate dihydrate		Others
	Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassiu...		Others
T33690	Nitroscanate	Lopatol,CGA-23654GS,CGA 23654
	Nitroscanate is an anthelmintic found to be effective in certain strains of parasites in canines.
T71841	MMV085203
	MMV08520 is a novel inhibitor of Plasmodium falciparum, killing both blood- and sexual-stage P. falciparum parasites.