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20

Compounds

Cat No. Product Name Synonyms Targets
T13865 Resorcinolnaphthalein RAAS
Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM).
T8158 Tilianin Others
Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L.
T2320 Indacaterol Adrenergic Receptor
Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.
TP1563 Gap19 Gap Junction Protein
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
T15108 DG-041 Prostaglandin Receptor
DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation of platelet aggregation and has the blood-brain barrier per...
T1265 Amrinone Inamrinone,Inocor,Wincoram TNF , PDE
Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity.
TN6490 Regaloside C Others
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.
T23312 SB 204741 5-HT Receptor
SB 204741 is a 5-HT2B receptor antagonist.
T9765 TJ-M2010-5 MyD88
TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.
T2671 Regadenoson CVT-3146,Lexiscan Adenosine Receptor
Regadenoson (CVT-3146) is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine re...
T23521 VULM 1457 Acyltransferase
VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of...
T15418 GS-6201 CVT-6883 Adenosine Receptor
GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM.
T1239 Indacaterol maleate QAB149 Adrenergic Receptor
Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.
T1479 Isosorbide dinitrate Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate Others , NO Synthase
Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.
T5329 Trandolapril Angiotensin-converting Enzyme (ACE)
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.
T28178 NLRP3-IN-9 INF-4E,INF 4E,INF4E NOD
NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- ...
T7714 Temocapil Tyrosinase
Temocapril is an inhibitor of tyrosine kinase.
T3461 Losartan Carboxylic Acid EXP-3174,E-3174 RAAS
Losartan Carboxylic Acid (E-3174) a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. Losartan Carboxylic Acid , a metabolite of losartan, is more potent than l...
T1046 Mexiletine hydrochloride KOE-1173 (hydrochloride),Mexiletine HCl,KO1173 AhR , Sodium Channel
Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myoca...
T9516 Binodenoson WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos Adenosine Receptor
Binodenoson (WRC 0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stres...
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