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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13865 | Resorcinolnaphthalein | RAAS | |
Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM). | |||
T8158 | Tilianin | Others | |
Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L. | |||
T2320 | Indacaterol | Adrenergic Receptor | |
Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist. | |||
TP1563 | Gap19 | Gap Junction Protein | |
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43. | |||
T15108 | DG-041 | Prostaglandin Receptor | |
DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation of platelet aggregation and has the blood-brain barrier per... | |||
T1265 | Amrinone | Inamrinone,Inocor,Wincoram | TNF , PDE |
Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity. | |||
TN6490 | Regaloside C | Others | |
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties. | |||
T23312 | SB 204741 | 5-HT Receptor | |
SB 204741 is a 5-HT2B receptor antagonist. | |||
T9765 | TJ-M2010-5 | MyD88 | |
TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies. | |||
T2671 | Regadenoson | CVT-3146,Lexiscan | Adenosine Receptor |
Regadenoson (CVT-3146) is an adenosine derivative and selective A2A adenosine receptor agonist with coronary vasodilating activity. Upon administration, regadenoson selectively binds to and activates the A2A adenosine re... | |||
T23521 | VULM 1457 | Acyltransferase | |
VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of... | |||
T15418 | GS-6201 | CVT-6883 | Adenosine Receptor |
GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM. | |||
T1239 | Indacaterol maleate | QAB149 | Adrenergic Receptor |
Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist. | |||
T1479 | Isosorbide dinitrate | Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate | Others , NO Synthase |
Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris. | |||
T5329 | Trandolapril | Angiotensin-converting Enzyme (ACE) | |
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat. | |||
T28178 | NLRP3-IN-9 | INF-4E,INF 4E,INF4E | NOD |
NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- ... | |||
T7714 | Temocapil | Tyrosinase | |
Temocapril is an inhibitor of tyrosine kinase. | |||
T3461 | Losartan Carboxylic Acid | EXP-3174,E-3174 | RAAS |
Losartan Carboxylic Acid (E-3174) a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. Losartan Carboxylic Acid , a metabolite of losartan, is more potent than l... | |||
T1046 | Mexiletine hydrochloride | KOE-1173 (hydrochloride),Mexiletine HCl,KO1173 | AhR , Sodium Channel |
Mexiletine hydrochloride (KOE-1173 hydrochloride) is a voltage-gated sodium channel blocker and a Class IB antiarrhythmic drug. Mexiletine hydrochloride exerts antiarrhythmic effects by inhibiting sodium current in myoca... | |||
T9516 | Binodenoson | WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos | Adenosine Receptor |
Binodenoson (WRC 0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stres... |