molecular — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9849	HQ461		CDK , Molecular Glues
	HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.		CDK , Molecular Glues
T18391	N-Boc-4-pentyne-1-amine		Others , PROTAC Linker
	N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound utilized in the synthesis of PROTAC MG-277[1].		Others , PROTAC Linker
T13206	Tris(2,4-di-tert-butylphenyl)phosphate		Phospholipase
	Tris(2,4-di-tert-butylphenyl)phosphate is a natural compound isolated from Vitex negundo L. with anti-inflammatory activity.		Phospholipase
T0213	Thalidomide	Thalomid,Sedoval	Apoptosis , TNF , Autophagy , Ligand for E3 Ligase , Molecular Glues
	Thalidomide (Thalomid) is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties.
T19031	NBD-F	4-Fluoro-7-nitrobenzofurazan	Others
	NBD-F (4-Fluoro-7-nitrobenzofurazan) is a fluorescent derivatization compound for amino acid analysis.		Others
T2384	Pomalidomide	CC-4047	Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
	Pomalidomide (CC-4047) inhibits TNF-α release in LPS stimulated human PBMCs (IC50: 13 nM). It is an anti-angiogenic agent and an immunomodulator.		Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
T22922	Lenalidomide hemihydrate		TNF , Ligand for E3 Ligase , Molecular Glues
	Lenalidomide hemihydrate is a TNF-α secretion inhibitor (IC50 = 13 nM). Lenalidomide hemihydrate could bound endogenous CRBN and recombinant CRBN-DNA damage binding protein-1 (DDB1) complexes.		TNF , Ligand for E3 Ligase , Molecular Glues
T10765	Eragidomide	CC-90009,Cereblon modulator 1	Apoptosis , Ligand for E3 Ligase , Molecular Glues
	Eragidomide (CC-90009; Cereblon modulator 1) is a cereblon (CRBN) E3 ligase modulator. Eragidomide specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.		Apoptosis , Ligand for E3 Ligase , Molecular Glues
T10703	Mezigdomide	CC-92480	Apoptosis , E1/E2/E3 Enzyme , Molecular Glues
	Mezigdomide (CC-92480) is a potent, novel, selective and active cereblon E3 ubiquitin ligase modulator (CELMoD) that often acts as a molecular glue. Mezigdomide has antimyeloma activity.		Apoptosis , E1/E2/E3 Enzyme , Molecular Glues
T1642	Lenalidomide	CC-5013	Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
	Lenalidomide (CC-5013) is a potent inhibitor of TNF-α that, at 10 μM, alters gene expression and cell viability in a range of cancer cell lines.		Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues
T6909	NSC348884		Apoptosis , p53
	NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines.		Apoptosis , p53
T17143	Toyocamycin	Vengicide	Apoptosis , Others , IRE1 , Antibiotic , Antifungal
	Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.		Apoptosis , Others , IRE1 , Antibiotic , Antifungal
T13667L1	Dusquetide aceate	Dusquetide aceate (931395-42-5 Free base)	Antibacterial
	Dusquetide aceate is an innate immune defense regulator against damage-associated molecular patterns and pathogen-associated molecular patterns. Dusquetide aceate shows anti-inflammation and antibacterial activities.		Antibacterial
TP1299L1	Melittin Acetate	Melittin Acetate(20449-79-0 Free base),Forapin Acetate	Phospholipase
	Melittin Acetate (Forapin Acetate) is a PLA2 activator. Melittin Acetate stimulates the activity of the low molecular weight PLA2, while it does not increase the activity of the high molecular weight PLA2.		Phospholipase
T6462	Deltarasin		PDE , Ras
	Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.		PDE , Ras
T1361	2-Trifluoromethyl thioxanthone		Others
	2-Trifluoromethyl thioxanthone is a pale yellow crystal with molecular fomula C14H7F3OS.		Others
T50103	NFAT Inhibitor-2		Others
	NFAT Inhibitor-2 is a compound used as a molecular building block.		Others
T14961	Chrysene	䓛	Others
	Chrysene is a high molecular weight (HMW), polycyclic aromatic hydrocarbon (PAH).		Others
T21644L	AF 12198 Acetate	AF 12198 Acetate (185413-30-3 Free base)	IL Receptor
	AF 12198 Acetate is a novel low molecular weight antagonist of IL-1		IL Receptor
T1373	AC-Beta-ALA-OH		Amino Acids and Derivatives
	It is an organic compounds with molecular fomula C5H9NO3.		Amino Acids and Derivatives