membrane — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP2198	Platelet Membrane Glycoprotein IIB Peptide (296-306)		Others
	GPllb is composed of a 125 Kd heavy chain that is disulfide-linked to a 23 Kd light chain. Hydropathicity analysis of the cDNA sequence indicates that GPllb is anchored to the platelet through a single transmembrane doma...		Others
T81824	Membrane-Permeable Sequence, MPS
	Membrane-Permeable Sequence (MPS) is a cell-penetrating peptide (CPP) utilized in the investigation of membrane crossing mechanisms [1].
T80209	Human membrane-bound PD-L1 polypeptide		PD-1/PD-L1
	Human membrane-bound PD-L1 polypeptide serves as an antigen for inducing the production of PD-L1 antibodies [1].		PD-1/PD-L1
T9423	Alkyne tyramide		Others
	Alkyne tyramide is a clickable ascorbate peroxidase 2 (APEX2) probe which enable biotin-independent detection of labeled proteins.		Others
T83737	LRRKtide TFA	Moesin (550-564),Membrane-organizing Extension Spike Protein (550-564)
	LRRKtide, a peptide substrate for leucine-rich repeat kinase 2 (LRRK2)—an enzyme often mutated in Parkinson's disease patients—corresponds to amino acids 550-564 of the membrane-organizing extension spike protein (moesin...
T21992	Vacuolin-1		PI3K , Autophagy
	Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits ...		PI3K , Autophagy
T9915	Eculizumab		Complement System
	Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5		Complement System
T83705	BING TFA	Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria
	BING, a antimicrobial peptide discovered in Japanese medaka fish (O. laptipes), originates from vacuolar protein sorting-associated protein 13D-like (Vps13D). It exhibits efficacy against a range of Gram-negative and Gra...
T14984	CLP257		Potassium Channel
	CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 alleviates hypersensitivity in rats with neuropathic painc and it al...		Potassium Channel
T11520	GW806742X		MLK , VEGFR
	GW806742X is an inhibitor of Mixed Lineage Kinase Domain-Like protein (MLKL) which binds the MLKL pseudokinase domain (Kd: 9.3 μM) with anti-necroptosis activity. GW806742X has activity against VEGFR2.		MLK , VEGFR
T21164	Sulfentrazone	FP-846	Others
	Sulfentrazone (FP-846) is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.It is a phenyl triazolinone herbicide		Others
T8946	Indophagolin		P2X Receptor , 5-HT Receptor , Autophagy
	Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively.		P2X Receptor , 5-HT Receptor , Autophagy
T8995	NCGC00262650		Others , Src
	NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.		Others , Src
T8851	I3MT-3	HMPSNE	Hippo pathway
	I3MT-3 (HMPSNE) (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST...		Hippo pathway
T10952	Dabuzalgron	Ro 115-1240	Apoptosis , Adrenergic Receptor
	Dabuzalgron (Ro 115-1240) is an orally active selective alpha-1A adrenergic receptor agonist used to treat urinary incontinence. Dabuzaron prevents cardiotoxicity caused by doxorubicin by maintaining mitochondrial functi...		Apoptosis , Adrenergic Receptor
T11282	FGTI-2734		Transferase
	FGTI-2734 is a dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor, exhibiting IC50 values of 250 nM and 520 nM for FT and GGT-1, respectively. It effectively prevents the membrane localizat...		Transferase
T2298	ML204		TRP/TRPV Channel
	ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.		TRP/TRPV Channel
T4947	3-Hydroxybutyric acid	Butanoic acid	Endogenous Metabolite
	3-Hydroxybutyric acid (Butanoic acid) (or beta-hydroxybutyrate) is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-hydroxybutyrate in blood and urine are raised in ketosis. In humans, ...		Endogenous Metabolite
T5827	BI-6C9		Apoptosis , Others , Mitochondrial Metabolism
	BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.		Apoptosis , Others , Mitochondrial Metabolism
T40996	Coppersensor 1	Coppersensor 1,CS1	Others
	Coppersensor 1 (CS1) is a boron dipyrromethene-based fluorescent sensor for selective and sensitive detection of copper(I) ions (Cu + ) in biological samples. Coppersensor 1 can be imaged using any type of fluorescence m...		Others