marrow — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5751	Tigogenin		Others
	Tigogenin is one of steroidal sapogenins which is widely used for synthesizing steroid drugs. It might have protective effect on bone and be helpful in preventing the development of osteoporosis.		Others
T2121	SW033291		Dehydrogenase
	SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.		Dehydrogenase
T8645	PF-06446846		Others
	PF 06446846 is a potent and selective PCSK9 inhibitor		Others
T8550	NDMC101		Others , NF-κB , Proteasome
	NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.		Others , NF-κB , Proteasome
T9026	MEISi-2	Benzoic acid, 4-hydroxy-, 2-[(Z)-(2-oxo-1(2H)-naphthalenylidene)methyl]hydrazide	Others
	MEISi-2 is a potent MEIS inhibitor (MEISi). MEISi-2 significantly inhibits MEIS-luciferase reporters in vitro.		Others
T9603	MNITMT
	MNITMT is a potent immunosuppressive agent without bone marrow toxicity [1].
T3004	Batilol	Batilolum,Stearyl monoglyceride,Batyl alcohol,1-O-Octadecylglycerol	Others , Endogenous Metabolite
	Batilol (Stearyl monoglyceride), isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.		Others , Endogenous Metabolite
T8400	Pamidronic acid		Wnt/beta-catenin
	Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells		Wnt/beta-catenin
T9171	Methenolone enanthate		Others
	Methenolone enanthate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.		Others
T25705	Imupedone	LF1695,LF-1695,LF 1695	Others
	Imupedone (LF 1695) is a synthetic immunomodulator that modulates T lymphocytes and macrophages, induces T-cell differentiation of bone marrow precursor cells, and increases the proliferative response of lymphocytes to m...		Others
T8117	Metenolone acetate	Methenolone acetate	Others , Androgen Receptor
	Metenolone acetate (Methenolone acetate) is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.		Others , Androgen Receptor
TN3209	3′,4′,7-Trihydroxyflavone		ATPase , Others , p38 MAPK , NF-κB
	3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone marrow derived macrophages (BMMs), it inhibits osteoclasto...		ATPase , Others , p38 MAPK , NF-κB
T1199	Mitotane	Mitotan,o,p'-DDD,NCI-C04933,2,4′-DDD	Apoptosis , AChR
	Mitotane (NCI-C04933) is a derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors a...		Apoptosis , AChR
T2820	Glycitin	Glycitein-7-β-O-glucoside,Glycitein 7-O-β-glucoside	Others , Influenza Virus , Antibacterial
	Glycitin (Glycitein 7-O-β-glucoside), a natural isoflavone isolated from legumes, can promote the proliferation of bone marrow stromal cells and osteoblasts and suppresses bone turnover.		Others , Influenza Virus , Antibacterial
TP1828	N-Acetyl-Ser-Asp-Lys-Pro		RAAS
	Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethalit...		RAAS
T9089	FTO-IN-1	UUN44923	Others
	UUN44923 is a FTO inhibitor. It may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS) , type 2 diabetes (T2D) , Alzheimer's diseases, breast cancers, small- cell lung cancers, a h...		Others
T1776L	Plerixafor octahydrochloride	JM3100 octahydrochloride,Plerixafor 8HCl (AMD3100 8HCl),Plerixafor 8HCl,SID791 octahydrochloride,AMD 3100 octahydrochloride,JM 3100 8HCl	Virus Protease , HIV Protease , CXCR
	Plerixafor octahydrochloride (JM3100 octahydrochloride) blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4, resulting in hematopoietic stem cell (HSC) release from bone marrow a...		Virus Protease , HIV Protease , CXCR
T76699	Sabatolimab	MBG453,NVP-MBG453	Others
	Sabatolimab (MBG453), a humanized IgG4 (S228P) antibody targeting TIM-3, is a potent inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab has potential immunosuppressive activity and selec...		Others
T14692	BMX-IN-1	BMX kinase inhibitor	BTK
	BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosine kinase (BTK, IC50 = 10.4 nM), but BMX-IN-1 is more than 47-656 ...		BTK
T3674	Hydroxysafflor yellow A	HSYA,Safflomin A	TGF-beta/Smad
	Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacit...		TGF-beta/Smad