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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6705 | TIC10 Isomer | ONC201 isomer,TIC10 Analogue | Others |
TIC10 Isomer (ONC201 isomer) is an isomer of TIC10, which inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improv... | |||
T71703L | Isomer-Turosteride | Isomer-Turosteride(Isomer-137099-09-3) | Reductase |
Isomer-Turosteride (Isomer-Turosteride(Isomer-137099-09-3)) is a novel 5 alpha-reductase inhibitor.The antiprostatic effect of Isomer-Turosteride in adult rats is associated with the inhibition of the conversion of T to ... | |||
T3700 | SCH900776 (S-isomer) | MK-8776 S-isomer,SCH900776 S-isomer | Chk , CDK |
SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 16... | |||
T6183 | ISRIB (trans-isomer) | ISRIB,ISRIB trans-isomer,trans-isomer,trans-ISRIB | Apoptosis , PERK , Autophagy |
ISRIB (trans-isomer) (ISRIB trans-isomer), the trans-isomer of ISRIB, is a effective and specific PERK inhibitor (IC50: 5 nM). | |||
T70470L | isomer-CM 352 | isomer-1542205-83-3 | MMP |
isomer-CM 352 is a metalase inhibitor that can be used to slow brain damage. | |||
T2280 | Endoxifen (Z-isomer) | Endoxifen Z-isomer | Estrogen Receptor/ERR , EGFR , Potassium Channel , Estrogen/progestogen Receptor , HER |
Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptors that also inhibits aromatase activity. | |||
T11200 | Endoxifen (E-isomer) | E-Endoxifen,Endoxifen E-isomer | Estrogen Receptor/ERR |
Endoxifen E-isomer (E-Endoxifen) is the E-isomer of (Z)-Endoxifen. Endoxifen E-isomer has antiestrogenic effects. | |||
T11758 | KI696 isomer | Nrf2 | |
KI696 isomer is an isomer of KI696, a low affinity probe for the study of immune and metabolic diseases. | |||
T19487 | NVP-BHG712 isomer | Ephrin Receptor | |
NVP-BHG712 isomer shows conserved non-bonded binding to EPHA2 and EPHB4. | |||
T27020L | isomer-Cilansetron | Others | |
isomer-Cilansetron is an isomer of Cilansetron. | |||
T27404L | isomer-GAT 107 | Others | |
isomer-GAT 107 ((-)GAT 107) is an inactive isomer of (+)GAT 107. | |||
T6286 | RGFP966 (E-isomer) | HDAC | |
RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC. | |||
T19114L | Sacubitril-(2S,4S)-Isomer | (2S,4S)-Sacubitril | Others |
Sacubitril-(2S,4S)-Isomer ((2S,4S)-Sacubitril) is the isomer of Sacubitril which is a neprilysin inhibitor. | |||
T10503 | ACAT-IN-1 cis isomer | Acyltransferase | |
ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM) for the study of immune system-related diseases. | |||
T60196 | IHMT-PI3Kδ-372 S-isomer | PI3K | |
IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM. IHMT-PI3Kδ-372 S-isomer shows high selectivity over other class I PI3Ks (56∼83 fold) and other protein kinases. IHMT-PI3Kδ-372 can ... | |||
T29020 | TSR-011-isomer | TSR011 isomer,TSR-011 isomer,Belizatinib isomer | |
TSR011-isomer, a TrKA/ALK inhibitor, is used potentially for the treatment of solid tumours and lymphoma. | |||
T11766 | Eltanexor Z-isomer | KPT-8602 (Z-isomer) | Others |
Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, < 100 nM, > 30 μM, respectively.Eltanexor Z-isomer is the less active isomer of KPT-8602. KPT-8602 is a... | |||
T26744 | BAY-598 R-isomer | BAY598 R-isomer,BAY 598 R-isomer | |
BAY-598 R-isomer is the R-isomer of BAY589, which is used as a reference compound. It is is an inhibitor of lysine N-methyltransferase (SMYD2) and is selective for SMYD2 over protease-activated receptor 1 (PAR1). | |||
T26322L | (-)-Vorozole | (-)-Vorozole(Isomer-129731-10-8) | P450 , Aromatase |
(-)-Vorozole is an orally active non-steroidal aromatase inhibitor with potency and selectivity. (-)-Vorozole has demonstrated antitumor activity in in vivo experiments. (-)-Vorozole is used in the study of breast cancer... | |||
T12155 | Y1 receptor antagonist 1 | H 409-22 isomer | Others |
Y1 receptor antagonist 1 is an antagonist of neuropeptide Y1 receptor. |