influx — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN1121	Evocarpine		Apoptosis , cAMP , Anti-infection , Calcium Channel , Antibacterial
	Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
T7736	2-Chloroadenosine		Adenosine Receptor
	2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively)		Adenosine Receptor
T8118	Bekanamycin	Kanamycin B	Antibacterial , Antibiotic
	Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic.		Antibacterial , Antibiotic
T6777	Bay K 8644	(±)-BAY-K-8644,SQ 28,873	Calcium Channel
	Bay K 8644 (SQ 28,873) is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.		Calcium Channel
T0370	Pheniramine maleate	Daneral,Inhiston,Trimetose	5-HT Receptor , Histamine Receptor
	Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re...		5-HT Receptor , Histamine Receptor
T40101	(±)-1,2-Diolein	1,2-Dioleoyl-rac-glycerol	PKC
	(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.		PKC
T2711	Chembridge-5861528	TCS 5861528	TRP/TRPV Channel
	Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM, respectively.		TRP/TRPV Channel
T6530	HC-030031	HC030031,TOSLAB 829227	TRP/TRPV Channel
	HC-030031 (TOSLAB 829227) is a potent TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC50s of 6.2±0.2 and 5.3±0.2 μM, respectively.		TRP/TRPV Channel
T12234	NMDA-IN-1		NMDAR
	NMDA-IN-1 is a potent and NR2B-selective antagonist of NMDA(NMDA Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM).		NMDAR
T23735	Jamaicin	An-Co-A4,AnCoA-4,An Co A4,AnCoA4	Calcium Channel
	Jamaicin (AnCoA4), an isoflavone derived from the chickweed plant, is an inhibitor of the STIM1-Orai1 channel that blocks calcium influx, reduces its interaction with STIM1, and inhibits T-cell activation.		Calcium Channel
TNU0864	HUP30		Potassium Channel , Calcium Channel
	HUP30 is a potent vasodilating agent. HUP30 can stimulate soluble guanylyl cyclase, activate K+ channels, and block extracellular Ca2+ influx.		Potassium Channel , Calcium Channel
T11102	DS16570511		Calcium Channel
	DS16570511 is a novel, cell-permeable inhibitor targeting the mitochondrial calcium uniporter. It effectively blocks the increase in Ca2+ influx dependent on MCU or MICU1 [1].		Calcium Channel
T5845	7ACC1	DEAC,Coumarin D 1421,7-(Diethylamino)coumarin-3-carboxylic acid,D 1421	Monocarboxylate transporter
	7ACC1 (D 142) selectively affects a single part of the MCT symporter translocation cycle, leading to strict inhibition of lactate influx. This singular activity is associated with antitumor effects less prone to resistan...		Monocarboxylate transporter
TN1154	Nepetin	6-Methoxyluteolin	Calcium Channel , Histamine Receptor
	Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain.		Calcium Channel , Histamine Receptor
T1768	7ACC2		Mitochondrial Metabolism , Monocarboxylate transporter
	7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.		Mitochondrial Metabolism , Monocarboxylate transporter
T16687	Pyr3		TRP/TRPV Channel
	Pyr3 is a selective transient receptor potential canonical channel 3 inhibitor. Pyr3 inhibits TRPC3-mediated Ca2+ influx in a dose-dependent manner(IC50 = 700 nM).		TRP/TRPV Channel
TN1136	Procyanidin A1	Proanthocyanidin A1	LDL , Calcium Channel , PKC
	Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an internal store in RBL-2H3 cells.		LDL , Calcium Channel , PKC
T1425	Pemirolast potassium	BMY 26517,TWT-8152	Histamine Receptor
	Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium (TWT-8152) exerts its action by blocking the antigen-mediated calcium ion influx i...		Histamine Receptor
T16688	Pyr6	N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide	TRP/TRPV Channel
	Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells).Pyr6 ...		TRP/TRPV Channel
T6645	Ropivacaine hydrochloride monohydrate	Ropivacaine HCl,Ropivacaine HCl monohydrate,LEA 103,LEA-103 HCl	Potassium Channel , Sodium Channel
	Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.		Potassium Channel , Sodium Channel