Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DS16570511 is a novel cell-permeable inhibitor of the mitochondrial calcium uniporter, which blocks the MCU- or MICU1-dependent increase of Ca 2+ influx [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 258.00 | |
5 mg | In stock | $ 642.00 | |
10 mg | In stock | $ 913.00 | |
25 mg | In stock | $ 1,370.00 | |
50 mg | In stock | $ 1,850.00 | |
100 mg | In stock | $ 2,500.00 |
Description | DS16570511 is a novel cell-permeable inhibitor of the mitochondrial calcium uniporter, which blocks the MCU- or MICU1-dependent increase of Ca 2+ influx [1]. |
In vitro | DS16570511 dose-dependently inhibits serum-induced mitochondrial Ca 2+ influx in HEK293A cells with an IC 50 of 7 μM [1]. DS16570511 inhibits Ca 2+ uptake of isolated mitochondria from human cells, rat heart as well as pig heart [1]. |
Molecular Weight | 562.44 |
Formula | C30H25Cl2N3O4 |
CAS No. | 2446154-84-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 124 mg/mL(220.47 mM)
You can also refer to dose conversion for different animals. More
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DS16570511 2446154-84-1 Membrane transporter/Ion channel Metabolism Calcium Channel DS-16570511 DS 16570511 inhibitor inhibit