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Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 76.00 | |
5 mg | In stock | $ 228.00 | |
10 mg | In stock | $ 372.00 | |
25 mg | In stock | $ 615.00 | |
50 mg | In stock | $ 869.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 223.00 |
Description | Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
In vitro | Using the human basophilic KU812F cells, we assessed the inhibitory effects of 6-Methoxyluteolin, isolated from Chrysanthemum zawadskii, in the FcαμRI-mediated allergic reaction. We determined that 6-Methoxyluteolin inhibited anti-FcαμRI α± chain antibody (CRA-1)-induced histamine release, as well as elevation of intracellular calcium concentration [Ca2+]i in a dose-dependent manner. Moreover, the inhibitory effects of 6-Methoxyluteolin on the cell surface expression and the mRNA level of the FcαμRI α± chain were determined by flow cytometric analysis and reverse transcription-polymerase chain reaction (RTPCR), respectively. |
Source |
Synonyms | 6-Methoxyluteolin |
Molecular Weight | 316.26 |
Formula | C16H12O7 |
CAS No. | 520-11-6 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (31.62 mM)
You can also refer to dose conversion for different animals. More
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Nepetin 520-11-6 GPCR/G Protein Immunology/Inflammation Membrane transporter/Ion channel Metabolism Neuroscience Calcium Channel Histamine Receptor Inhibitor 6-Methoxyluteolin inhibit inhibitor