hepatic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T83064	Anti-hepatic fibrosis agent 2
	Compound 6k, also known as Anti-hepatic fibrosis agent 2, is an orally active inhibitor of the COL1A1 enzyme and exerts anti-fibrogenic effects by targeting the Ewing sarcoma breakpoint region 1 (EWSR1)[1].
TD0093	Oil Red O		Others
	The dry dye Oil red O is used for the preparation of a staining solution that can be used for the detection of lipids in histological cryo sections.		Others
T12580	PTUPB		COX , Epoxide Hydrolase
	PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively).		COX , Epoxide Hydrolase
T7992	4-Hydroxyflavanone		NO Synthase
	4-Hydroxyflavanone is a natural product, shows full vasorelaxing effects		NO Synthase
T12490	Pitavastatin lactone		Others
	Pitavastatin lactone is a major Pitavastatin metabolite in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes.		Others
T13173	TMPA		Others , AMPK
	TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.		Others , AMPK
T4410	LM10		Others
	Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters....		Others
T31976	Glymidine sodium		Others
	Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion.		Others
T1403	Climbazole	BAY-e 6975	Antibiotic , Antifungal
	Climbazole (BAY-e 6975) is a broad-spectrum imidazole antifungal agent with anti-dandruff benefits.		Antibiotic , Antifungal
T3888	Scopolin	Murrayin,Scopoloside	Sirtuin
	Scopolin (Scopoloside) formation is increased by the enhanced activity of PAL. Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for...		Sirtuin
T5045	GSK4112	1,1-Dimethylethyl-N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl])glycinate,SR6452	Autophagy
	GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.		Autophagy
T3858	Macranthoidin A		Others
	Macranthoidin A has anti-inflammation activity.		Others
T3124	Carbendazim	Bavistin,Carbendazole,Mercarzole	Antifungal
	Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec...		Antifungal
T0462	Cilostazol	OPC 21,OPC 13013	PDE , Autophagy
	Cilostazol (OPC 21) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of cilostazol is as a Phosphodiesterase 3 Inhibitor.		PDE , Autophagy
T0850	Primaquine diphosphate	Primaquine phosphate,Primaquine bisphosphate	Antibiotic , Parasite
	Primaquine diphosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the proper...		Antibiotic , Parasite
T0746	Orotic acid	Vitamin B13,6-Carboxyuracil	Nucleoside Antimetabolite/Analog , Dehydrogenase , Endogenous Metabolite
	Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism.
T2718	Palmatine chloride		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
	Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
T9195	SHR0302	ARQ252	Apoptosis , JAK
	SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).		Apoptosis , JAK
T1410	Torsemide	AC-4464,JDL-464,Torasemide	Na-K-Cl cotransporter
	Torsemide (AC-4464) is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and h...		Na-K-Cl cotransporter
T19081	1,3-Dithiane	1,3-Dithian,M-DITHIANE,1,3-Dithiacyclohexane	Anti-infection , Endogenous Metabolite , Antibacterial
	1,3-Dithiane (1,3-Dithian) is a protected formaldehyde anion equivalent that could serve as a useful labeled synthon. 1,3-Dithiane is also a sulfur-containing Maillard reaction products found in boiled beef extracts.		Anti-infection , Endogenous Metabolite , Antibacterial