Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 39.00 | |
25 mg | In stock | $ 81.00 | |
50 mg | In stock | $ 147.00 | |
100 mg | In stock | $ 247.00 | |
200 mg | In stock | $ 368.00 | |
500 mg | In stock | $ 596.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 29.00 |
Description | Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815 mastocytoma tumors in mice. Orally bioavailable. |
Targets&IC50 | TDO (human):0.62 μM, TDO (mouse):2 μM |
Molecular Weight | 229.21 |
Formula | C11H8FN5 |
CAS No. | 1316695-35-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 4.58 mg/mL(20 mM)
DMSO: 22.92 mg/mL(100 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
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