enzymatic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19161	7α-Hydroxycholesterol		Others
	7α-Hydroxycholesterol is a cholesterol oxide formed by both enzymatic and non-enzymatic oxidation. It can be used as a biomarker for lipid peroxidation.		Others
T41044	Naringinase		Glucosidase
	Naringinase is a hydrolytic enzymatic complex that exhibits α-L-rhamnosidase and β-D-glucosidase activities. It is widely found in nature and is primarily utilized for the biotransformation of steroids, antibiotics, and ...		Glucosidase
TN1733	Hesperetin 7-O-glucoside		Anti-infection , Antibacterial , HMG-CoA Reductase
	Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA reductase, it also exhibits effective inh...		Anti-infection , Antibacterial , HMG-CoA Reductase
TD0099	Malachite green oxalate		Apoptosis , Others , IκB/IKK , NF-κB
	Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.		Apoptosis , Others , IκB/IKK , NF-κB
T11374	GCN2-IN-6		Others , PERK
	GCN2-IN-6 is also a eIF2α kinase PERK inhibitor with an IC50 of 0.26 nM (in enzymatic assay) and 230 nM (in cells). GCN2-IN-6 is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50 of 1.8...		Others , PERK
T19356	HTBA		Others
	HTBA is a low-cost enzymatic paper-based analytical device (enz-PAD) for determining urine creatinine.		Others
T41032	Lysostaphin		Antibacterial
	Lysostaphin is a potent antistaphylococcal compound that exhibits enzymatic activity through three distinct enzymes: glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase, and N-acetyl muramyl-L-alanine amidase.		Antibacterial
T6076	EPZ015666	GSK3235025	Histone Methyltransferase
	EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 enzymatic activity.		Histone Methyltransferase
T2242	Wnt-C59	C59	Wnt/beta-catenin , Porcupine
	Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity.		Wnt/beta-catenin , Porcupine
T21089	Nitrophenide	3,3'-Dinitrodiphenyl disulfide	Dehydrogenase
	Nitrophenide (3,3'-Dinitrodiphenyl disulfide) inhibits mannitol-1-phosphate dehydrogenase (M1PDH), which catalyzes the committed enzymatic step in the mannitol cycle. Nitrophenide can be used as an anticoccidial agent.		Dehydrogenase
T37082	HS271		IRAK
	HS271 is a selective, highly potent and orally active IRAK4 inhibitor (IC50= 7.2 μM). HS271 shows excellent enzymatic and cellular activities, as well as excellent pharmacokinetic properties.		IRAK
T7109	TMB-PS	TMBZ-PS	Others
	TMB-PS (TMBZ-PS) is a chromogenic reagent for the detection of hydrogen peroxide e.g. in the enzymatic analysis of body fluids.		Others
T3415	Secoisolariciresinol diglucoside	LGM2605	ROS
	Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect ...		ROS
T19522	PNPG	4-Nitrophenyl β-D-glucopyranoside	Others
	PNPG (4-Nitrophenyl β-D-glucopyranoside) is a chromogenic substrate for β-D-glucosidase that, upon enzymatic cleavage, yields a yellow solution.		Others
T7181	IDO-IN-1		Indoleamine 2,3-Dioxygenase (IDO)
	IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively.)		Indoleamine 2,3-Dioxygenase (IDO)
TN1414	Aurantio-obtusin β-D-glucoside	Aurantio-obtusin beta-D-glucoside	Others
	Aurantio-obtusin β-D-glucoside (Aurantio-obtusin beta-D-glucoside) is a natural product originated from the enzymatic cleavage of its glucoside glucoaurantio-obtusin.		Others
T8428	Subasumstat	TAK-981	E1/E2/E3 Enzyme
	Subasumstat (TAK-981) is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities.		E1/E2/E3 Enzyme
T1866	AT-56		Others , PGE Synthase
	AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects.		Others , PGE Synthase
T3209	AMG-337	AMG337	c-Met/HGFR
	AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337(AMG337) inhibits MET kinase activity (IC50: < 5 nM).		c-Met/HGFR
T14501	BAY-2402234		Dehydrogenase , DNA/RNA Synthesis
	BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity.		Dehydrogenase , DNA/RNA Synthesis