end — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6S2384	Poliumoside		Reductase
	Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase w...		Reductase
T10981	DCZ0415		Apoptosis , Others , NF-κB
	DCZ0415 induces antimyeloma activity in vitro, in vivo and in primary cells of drug-resistant myeloma patients. DCZ0415 is a potent TRIP13 inhibitor that can impair the repair of non-homologous end junctions and inhibit ...		Apoptosis , Others , NF-κB
T1724	SCR7 pyrazine	SCR7	Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
	SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).		Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
TN1471	Cassiaside C	Toralactone 9-O-β-D-gentiobioside	Others , Endogenous Metabolite
	Cassiaside C (Toralactone 9-O-β-D-gentiobioside), a naphthopyrone extracted from Cassia tora seeds, exhibits in vitro inhibitory activity against the formation of advanced glycation end products (AGE).		Others , Endogenous Metabolite
T7369L	Gemigliptin Tartrate(911637-19-9 free base)	LC15-0444 tartrate	Proteasome , DPP-4
	Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibit...		Proteasome , DPP-4
T3340	SCR7		Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
	SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).		Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
T4281	Endoxifen	(E/Z)-N-desmethyl-4-hydroxy Tamoxifen,(E/Z)-Endoxifen	Estrogen Receptor/ERR , Aromatase , Estrogen/progestogen Receptor , Parasite , Drug Metabolite
	(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-f...
T3361	Cambendazole	Bonlam,MK-905,Novazole	Others
	Cambendazole (Novazole) is one of the most effective agents for the therapy of human strongyloidiasis. Cambendazole is a nematocide effective against a variety of gastrointestinal parasites in cattle, sheep, and horses.		Others
T19309L1	Endothelin 1 (swine, human) acetate	Endothelin 1 (swine, human) acetate(117399-94-7 free base)	Endothelin Receptor
	Endothelin 1 (swine, human) acetate is a synthetic peptide with the sequence of human and swine Endothelin 1. Endothelin 1 is a potent endogenous vasoconstrictor and acts through two types of receptors ETA and ETB.		Endothelin Receptor
TP1174	Endothelin-2 (49-69), human	Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine)	Others
	Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.		Others
T67954	Endixaprine	SR 41378
	Endixaprine (SR 41378) is a small molecule compound used to treat neurological disorders and may be used to study anxiety disorders and epilepsy.
T21511L	Alpha-Endorphin acetate	alpha-Endorphin acetate (59004-96-5 Free base)	Others
	alpha-Endorphin acetate is related peptides of the pro-opiomelanocortin family with characteristic biological activities, were purified to homogeneity from single human pituitary.		Others
T63808	Cap-dependent endonuclease-IN-1		Others
	Cap-dependent endonuclease-IN-1 is a highly potent and orally active cap-dependent endonuclease inhibitor with antiviral activity for the study of influenza virus infection.		Others
T22540L	Ac-Endothelin-1 (16-21), human acetate		Others
	Ac-Endothelin-1 (16-21), human acetate, the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which i...		Others
T7218	Endomorphin 2		Opioid Receptor
	Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers f...		Opioid Receptor
TP2322L	Beta-Neoendorphin acetate(77739-21-0 free base)		Opioid Receptor
	beta-Neoendorphin acetate is an agonist of κ-opioid receptor		Opioid Receptor
T5S0777	Phellodendrine chloride		Others
	Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.		Others
T19967	Fendosal	HP 129,P 71-0129,P71-0129,P-71-0129,HP129,HP-129	Immunology/Inflammation related
	Fendosal (HP-129) is a non-steroidal anti-inflammatory agent. It is 6.9 to 9.5 times more active than aspirin in the prophylactic and therapeutic adjuvant-induced polyarthritis models of chronic inflammation.		Immunology/Inflammation related
T4182	Lavendustin B		Tyrosinase , transporter , HIV Protease
	Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75).		Tyrosinase , transporter , HIV Protease
T6623	Oxibendazole		Apoptosis , Parasite
	Oxibendazole is a benzimidazole drug that interferes with metabolic pathways, used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets.		Apoptosis , Parasite