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Gemigliptin Tartrate(911637-19-9 free base)

Gemigliptin Tartrate(911637-19-9 free base)
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Gemigliptin Tartrate(911637-19-9 free base)

Catalog No. T7369LCas No. 1374639-74-3
Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties.
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Pack SizePriceAvailabilityQuantity
2 mg$34In Stock
5 mg$55In Stock
10 mg$89In Stock
25 mg$159In Stock
50 mg$272In Stock
1 mL x 10 mM (in DMSO)$97In Stock
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Product Introduction

Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties.
In vitro
Gemigliptin tartrate inhibits the formation of AGE-BSA with IC50 of 11.69 mM[1]. Gemigliptin tartrate suppresses the cross-linking of preformed AGE-BSA with rat tail tendon collagen with an IC50 of 1.39 mM[1]. Gemigliptin tartrate is a competitive DPP-4 inhibitor with a Ki of 7.25 nM[2].
In vivo
Gemigliptin tartrate inhibits AGEs formation and AGE cross-links in vivo[1]. Gemigliptin tartrate dose-dependently inhibits plasma DPP-4 activity in rats, dogs, and monkeys[2].
AliasLC15-0444 tartrate
Chemical Properties
Molecular Weight639.45
Cas No.1374639-74-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 90 mg/mL(140.75 mM)
Solution Preparation Table
1 mM1.5638 mL7.8192 mL15.6384 mL78.1922 mL
5 mM0.3128 mL1.5638 mL3.1277 mL15.6384 mL
10 mM0.1564 mL0.7819 mL1.5638 mL7.8192 mL
20 mM0.0782 mL0.3910 mL0.7819 mL3.9096 mL
50 mM0.0313 mL0.1564 mL0.3128 mL1.5638 mL
100 mM0.0156 mL0.0782 mL0.1564 mL0.7819 mL


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