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Search Results for " dementia "

20

Compounds

Cat No. Product Name Synonyms Targets
T9989 AChE-IN-27 Others
AChE-IN-27 is a small molecule used for high-throughput assays.
T0322 Fipexide Dopamine Receptor , AChR
Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is...
T4954 SMILAGENIN ACETATE Nsc15488 Others
Smilagenin acetate is a sapogenin derivative that has been shown to upregulate the expression of the acetylcholine M2 receptor in cell assays, making it a candidate for dementia research.
T3394 Timosaponin BII Prototimosaponin A III Beta Amyloid , Others , BACE
Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the...
T3885 ROSIRIDIN 6'-O-Deacetylrosiridoside C,(-)-Rosiridin Others , Monoamine Oxidase
Rosiridin (6'-O-Deacetylrosiridoside C) has cardioprotective activity.
T14991 CMS-121 CMS121 Acetyl-CoA Carboxylase
CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect...
T7792 Hispidin Endogenous Metabolite , PKC
Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties
T31175 Dabelotine UNII-6RY56RB98P Adrenergic Receptor
Dabelotine (UNII-6RY56RB98P) is an adrenergic agonist used in the study of dementia.
T19812 Propentofylline HWA-285,Karsivan,Propentophylline,Hextol,HWA 285,HWA285 PDE
Propentofylline (Hextol) is a methylxanthine derivative with neuroprotective, antiproliferative, and anti-inflammatory activity and enhanced synaptic adenosine signaling, which may be useful in the study of Alzheimer's d...
T27795 Landipirdine RO 5025181,RO5025181,SYN-120,SYN120,RO-5025181,SYN 120 5-HT Receptor
Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.
T3S1816 Parishin B Others
1. Parishin B can prevent vascular dementia.
T26526 Abt-288 ABT 288,ABT288 Histamine Receptor
ABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate Alzheimer's dementia.
T25226 Ceronapril Ceronaprilum,SQ 29852,SQ-29852,SQ29852 RAAS
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.
T34114 Posatirelin BRN 6006446,Posatirelinum,BRN-6006446,RGH-2202,BRN6006446 AChR
Posatirelin (BRN6006446) is a synthetic peptide with modulatory activity and neurotrophic effects on monoaminergic and cholinergic systems for the study of vascular dementia.
T61807 5-HT6/7 antagonist 1 Dopamine Receptor , 5-HT Receptor
5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.
T7041 Donepezil E2020,Donepezilo,Aricept AChE
Donepezil (Aricept) is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate dementia of the Alzheimer's type.
T31592 E6801 E 6801,E-6801 5-HT Receptor
E6801 is a novel selective 5-HT6 receptor agonist with a wide range of biological activities.E6801 can be used in the study of dementia, Parkinson's disease, depression, obesity epilepsy, anxiety, and many other diseases...
T11949 Masupirdine mesylate SUVN-502 mesylate,SVN-502 mesylate 5-HT Receptor
Masupirdine mesylate (SUVN-502 mesylate) is a selective 5-HT6 receptor antagonist that crosses the blood-brain barrier.Masupirdine mesylate is used in the study of neurological disorders such as Alzheimer's disease and d...
T67941 PDE5-IN-9
PDE5-IN-9 inhibits Phosphodiesterase PDE1c and is used to treat hypertension, heart failure, myocardial infarction, kidney failure, asthma, bronchitis, and dementia.
T7525 Didox NSC-324360 DNA/RNA Synthesis
Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor that has been found to reduce the levels of oxidative injury markers in the brains of HIV patients with dementia.
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TargetMol