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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9989 | AChE-IN-27 | Others | |
AChE-IN-27 is a small molecule used for high-throughput assays. | |||
T0322 | Fipexide | Dopamine Receptor , AChR | |
Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is... | |||
T4954 | SMILAGENIN ACETATE | Nsc15488 | Others |
Smilagenin acetate is a sapogenin derivative that has been shown to upregulate the expression of the acetylcholine M2 receptor in cell assays, making it a candidate for dementia research. | |||
T3394 | Timosaponin BII | Prototimosaponin A III | Beta Amyloid , Others , BACE |
Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the... | |||
T3885 | ROSIRIDIN | 6'-O-Deacetylrosiridoside C,(-)-Rosiridin | Others , Monoamine Oxidase |
Rosiridin (6'-O-Deacetylrosiridoside C) has cardioprotective activity. | |||
T14991 | CMS-121 | CMS121 | Acetyl-CoA Carboxylase |
CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect... | |||
T7792 | Hispidin | Endogenous Metabolite , PKC | |
Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties | |||
T31175 | Dabelotine | UNII-6RY56RB98P | Adrenergic Receptor |
Dabelotine (UNII-6RY56RB98P) is an adrenergic agonist used in the study of dementia. | |||
T19812 | Propentofylline | HWA-285,Karsivan,Propentophylline,Hextol,HWA 285,HWA285 | PDE |
Propentofylline (Hextol) is a methylxanthine derivative with neuroprotective, antiproliferative, and anti-inflammatory activity and enhanced synaptic adenosine signaling, which may be useful in the study of Alzheimer's d... | |||
T27795 | Landipirdine | RO 5025181,RO5025181,SYN-120,SYN120,RO-5025181,SYN 120 | 5-HT Receptor |
Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia. | |||
T3S1816 | Parishin B | Others | |
1. Parishin B can prevent vascular dementia. | |||
T26526 | Abt-288 | ABT 288,ABT288 | Histamine Receptor |
ABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate Alzheimer's dementia. | |||
T25226 | Ceronapril | Ceronaprilum,SQ 29852,SQ-29852,SQ29852 | RAAS |
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension. | |||
T34114 | Posatirelin | BRN 6006446,Posatirelinum,BRN-6006446,RGH-2202,BRN6006446 | AChR |
Posatirelin (BRN6006446) is a synthetic peptide with modulatory activity and neurotrophic effects on monoaminergic and cholinergic systems for the study of vascular dementia. | |||
T61807 | 5-HT6/7 antagonist 1 | Dopamine Receptor , 5-HT Receptor | |
5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease. | |||
T7041 | Donepezil | E2020,Donepezilo,Aricept | AChE |
Donepezil (Aricept) is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate dementia of the Alzheimer's type. | |||
T31592 | E6801 | E 6801,E-6801 | 5-HT Receptor |
E6801 is a novel selective 5-HT6 receptor agonist with a wide range of biological activities.E6801 can be used in the study of dementia, Parkinson's disease, depression, obesity epilepsy, anxiety, and many other diseases... | |||
T11949 | Masupirdine mesylate | SUVN-502 mesylate,SVN-502 mesylate | 5-HT Receptor |
Masupirdine mesylate (SUVN-502 mesylate) is a selective 5-HT6 receptor antagonist that crosses the blood-brain barrier.Masupirdine mesylate is used in the study of neurological disorders such as Alzheimer's disease and d... | |||
T67941 | PDE5-IN-9 | ||
PDE5-IN-9 inhibits Phosphodiesterase PDE1c and is used to treat hypertension, heart failure, myocardial infarction, kidney failure, asthma, bronchitis, and dementia. | |||
T7525 | Didox | NSC-324360 | DNA/RNA Synthesis |
Didox (NSC-324360) is a synthetic ribonucleotide reductase (RR) inhibitor that has been found to reduce the levels of oxidative injury markers in the brains of HIV patients with dementia. |