defense — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TQ0211	Brusatol	(+)-Brusatol,NSC 172924	Others , Ferroptosis , Nrf2
	Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.		Others , Ferroptosis , Nrf2
TN2216	Alpha-Solamarine	Solamarine
	Alpha-Solamarine (Solamarine) is a glycoside alkaloid isolated from Solanum nigrum.Alpha-Solamarine is inhibitory to Globodera pallid and may be used for plant defense.
T34295	Resiniferatoxin	RTX,[3H]resiniferatoxin	IL Receptor
	Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response.		IL Receptor
T13667L1	Dusquetide aceate	Dusquetide aceate (931395-42-5 Free base)	Antibacterial
	Dusquetide aceate is an innate immune defense regulator against damage-associated molecular patterns and pathogen-associated molecular patterns. Dusquetide aceate shows anti-inflammation and antibacterial activities.		Antibacterial
TN7040	Taxifolin 7-O-β-D-glucoside	Taxifolin 7-Glucoside	Others
	Taxifolin 7-O-β-D-glucoside is a flavonoid mainly found in endosperm and involved in defense against pathogens and UV damage.		Others
T2S2264	Linalool	Linalol,(±)-Linalool,Phantol	Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
	1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
T8076	Cis-Jasmone	Jasmone	Others
	cis-Jasmone is a natural product isolated from the volatile portion of the oil from jasmine flowers,as an insect semiochemical and in plant defense		Others
T27064	CP-312	CP312,Cardioprotectant 312	Reactive Oxygen Species , Autophagy
	CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1...		Reactive Oxygen Species , Autophagy
T5076	L-Allothreonine	L-allo-Threonine	Others , Endogenous Metabolite
	L-Allothreonine (L-allo-Threonine) is an essential amino acid in humans. L-Allothreonine is abundant in human plasma, particularly in newborns. Severe deficiency of threonine causes neurological dysfunction and lameness ...		Others , Endogenous Metabolite
T1435	Praziquantel	Pyquiton,Droncit,Biltricide	Calcium Channel , Antibiotic , Parasite
	Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculatur...		Calcium Channel , Antibiotic , Parasite
T124384	Jasmonic acid	(-)-Jasmonic acid
	Jasmonic acid (JA) is a phytohormone and plant growth regulator involved in plant defense and growth and development.Jasmonic acid plays an important role in signaling, inducing the MAP kinase cascade pathway and calcium...
T6S0525	Farrerol		ERK , p38 MAPK , Akt
	1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3....		ERK , p38 MAPK , Akt
T1562	Rebamipide	Proamipide,OPC12759	Free radical scavengers , COX , Prostaglandin Receptor
	Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis ...		Free radical scavengers , COX , Prostaglandin Receptor
T60522	Letosteine	Viscotiol	Others
	Letosteine (Viscotiol) is an orally active, effective, and safe expectorant that can be used in the study of acute or chronic respiratory diseases, for example, bronchopulmonary disease. Letosteine dissolves bronchial mu...		Others
T0920	Ambroxol	Ambroxolum,NA-872	P450 , Autophagy
	Ambroxol (NA-872) is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a muco...		P450 , Autophagy
T6S1572	Sauchinone		ERK , p38 MAPK , NF-κB
	1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...		ERK , p38 MAPK , NF-κB
T39179	β-Tomatine
	β-Tomatine, a derivative of α-tomatine, is a fungitoxic compound that efficiently inhibits plant defense responses.
T40936	Quinclorac
	Quinclorac, a commonly used agricultural herbicide, elicits oxidative stress by triggering the production of free radicals and altering the antioxidant defense system.
T19801	Acibenzolar-S-methyl	Bion, BTH,Bendicar,Acibenzolar S methyl,Acibenzolar S-methyl,Actigard
	Acibenzolar-S-methyl is a fungicide. Acibenzolar-S-methyl works by activating a plant's own defense system by increasing the transcription of W-box controlled genes such as CAD1, NPR1, and PR2.
T40327	Tetra-N-acetylchitotetraose
	Tetra-N-acetylchitotetraose, a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia, stimulates plant defense systems. Moreover, it serves as a substrate for the CO deacetylase nodulation protein NodB i...