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Farrerol

Catalog No. T6S0525 CAS 24211-30-1

1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3. Farrerol inactivates KEAP-1 or activates the Akt, p38 and ERK to facilitate the release of Nrf2 from Keap1 and subsequent reduces the intracellular production of reactive oxygen species via the induction of HO-1 expression. 4. Farrerol has protective effects against H2O2-induced apoptosis in EA.hy926 cells, and suggests that Farrerol is a potential candidate for the intervention of endothelial-injury-associated cardiovascular diseases.

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Farrerol, CAS 24211-30-1

Pack Size	Availability	Price/USD	Quantity
20 mg	In stock	$ 110.00
1 mL * 10 mM (in DMSO)	In stock	$ 70.00

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Purity: 99.96%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Source

Natural Products > Ericaceae > Rhododendron

Molecular Weight	300.31
Formula	C17H16O5
CAS No.	24211-30-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

DMSO: 55 mg/mL(183.1 mM)

References and Literature

1. Liu E , Liang T , Wang X , et al. Apoptosis induced by farrerol in human gastric cancer SGC-7901 cells through the mitochondrial-mediated pathway[J]. European journal of cancer prevention: the official journal of the European Cancer Prevention Organisation (ECP), 2015, 24(5):365.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Cancer Cell Differentiation Compound Library Anti-Obesity Compound Library Anti-Inflammatory Traditional Chinese Medicine Compound Library Anti-Tumor Natural Product Library Stem Cell Differentiation Compound Library Neural Regeneration Compound Library RO5 Drug-like Natural Product Library Bioactive Compounds Library Max Oxidation-Reduction Compound Library

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Keywords

Farrerol 24211-30-1 Cytoskeletal Signaling MAPK PI3K/Akt/mTOR signaling ERK p38 MAPK Akt inhibit Inhibitor inhibitor

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