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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11363 | Ganoderic acid F | Others | |
Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium si... | |||
T12579 | RAMB4 | PTP1B-IN-9 | Proteasome |
RAMB4 (PTP1B-IN-9) is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity. | |||
T0023 | Valethamate bromide | Ediposin,Epidozin,Epidosin,Resitan | Others |
Valethamate bromide (Resitan) is an anticholinergic agent that has antispasmodic effects and inhibits glandular secretion. | |||
T5S1133 | Ganoderic acid D | Apoptosis , Sirtuin | |
1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 micr... | |||
T20029 | Buformin hydrochloride | NSC528218,NSC-528218,NSC 528218 | AMPK |
Buformin hydrochloride (NSC-528218) is a potent AMPK activator,an oral antidiabetic drug of the biguanide class. Buformin delays the absorption of glucose from the gastrointestinal tract increases insulin sensitivity and... | |||
T22450 | Tyrphostin B44, (+) enantiomer | EGFR | |
Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer. | |||
T13475 | β-Aminopropionitrile | 3-Aminopropionitrile,BAPN | Others , Endogenous Metabolite |
β-Aminopropionitrile (3-Aminopropionitrile) is a selective inhibitor of lysyl oxidase. | |||
T14046 | Anandamide | (5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide | Cannabinoid Receptor , Endogenous Metabolite |
Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy... | |||
TP1283L | VIP(6-28)(human, rat, porcine, bovine) acetate | Others | |
VIP(6-28)(human, rat, porcine, bovine) acetate is an antagonist of the actions of exogenous vasoactive intestinal peptide (VIP) receptor on cAMP in the superior cervical ganglion (SCG). | |||
T20742 | TG-89 | FLT , c-RET , JAK | |
TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian and cervical cancer. | |||
T23867 | Cdc7-IN-7c | Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c | CDK |
Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer. | |||
TP1554L | HPV16 E7 (86-93) acetate | HPV16 E7 (86-93) acetate(160212-93-1 Free base) | Others |
HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas. | |||
T6858 | Hydroxyprogesterone caproate | Primolut Depot,Delalutin,Hormofort,17α-Hydroxyprogesterone hexanoate,17α-Hydroxyprogesterone caproate | Autophagy |
Hydroxyprogesterone caproate (Delalutin) is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical m... | |||
T60485 | DIF-3 | ||
DIF-3 is a chemical compound that acts by activating GSK-3β to facilitate the degradation of cyclin D1 and c-Myc, resulting in reduced expression levels of these proteins. In addition, DIF-3 inhibits Wnt/β-catenin signal... | |||
T27612 | INI-43 | INI 43,INI43 | Others |
INI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpn... | |||
TN6730 | Epoxyazadiradione | NF-κB | |
Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells. | |||
T8787 | Drotaverine hydrochloride | PDE | |
Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor,and is an antispasmodic drug, used to enhance cervical dilation during childbirth. Drotaverine hydrochloride is structurally rela... | |||
T4036 | Solasodine | Solancarpidine,Purapuridine,Solasodin | Apoptosis , Others , E1/E2/E3 Enzyme , Antifungal |
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer cell line (HeLa) and huma... | |||
T2597 | Norgestrel | SH-850,FH 122-A,WY-3707,SH-70850 | Estrogen/progestogen Receptor , Reactive Oxygen Species |
Norgestrel (WY-3707) is a synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), t... | |||
T67786 | ABI-1968 PM | ||
ABI-1968 PM is a derivative of ABI-1968, an apoptosis-stimulating agent and an inhibitor of viral replication.ABI-1968 can be used to study cervical intraepithelial neoplasia, papillomavirus infection, and squamous intra... |