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TG-89

Catalog No. T20742 CAS 936091-56-4

TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian and cervical cancer.

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TG-89, CAS 936091-56-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 94.00
5 mg	In stock	$ 263.00
10 mg	In stock	$ 416.00
25 mg	In stock	$ 692.00
50 mg	In stock	$ 985.00
100 mg	In stock	$ 1,330.00
500 mg	In stock	$ 2,660.00

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Purity: 98.8%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	TG-89 is an inhibitor of JAK2, JAK3, RET and FLT3, and has an IC50 value of 11.2 μM against JAK2, showing anticancer activity in the treatment of ovarian and cervical cancer.
Targets&IC50	JAK2:11.2 μM

Molecular Weight	510.65
Formula	C26H34N6O3S
CAS No.	936091-56-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 9.0 mg/mL (17.6 mM)

References and Literature

1. FURUKAWA Y, et al. Acute and subacute toxicities of azulene gargle (TG-89) containing azulene sodium sulfonate[J]. ORAL THERAPEUTICS AND PHARMACOLOGY, 1990, 9(3): 157-165.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Inhibitor Library Tyrosine Kinase Inhibitor Library Bioactive Compounds Library Max Bioactive Compound Library Anti-Cancer Compound Library Kinase Inhibitor Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

TG-89 936091-56-4 Angiogenesis Apoptosis Chromatin/Epigenetic JAK/STAT signaling Stem Cells Tyrosine Kinase/Adaptors FLT c-RET JAK TG 89 TG89 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.