20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35407 | Ζ-Stat | PKC | |
ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in melanoma cell lines, exhibiting antitumor activity in vitro[1]... | |||
T4576 | Perospirone | Lullan | Dopamine Receptor , 5-HT Receptor |
Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist. | |||
T1539 | Iloperidone | HP 873 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Iloperidone (HP 873) is an atypical antipsychotic agent that is used for treatment of schizophrenia. | |||
T0076 | Paliperidone | 9-hydroxyrisperidone | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor |
Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic. It applies to the acute and maintenance treatment of schizophrenia. Chemically, paliperidone is the primary active metabolite of the older... | |||
T5189 | Omadacycline | PTK 0796,Amadacycline | ribosome , Antibacterial , Antibiotic |
Omadacycline (Amadacycline), a new tetracycline antibiotic, can inhibit the 30s subunit of bacterial ribosome. | |||
T9189 | Iptacopan hydrochloride | Iptacopan HCl,LNP023 hydrochloride | Complement System |
Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity b... | |||
T8136 | Perospirone hydrochloride | Perospirone HCl,SM-9018 hydrochloride | Dopamine Receptor , 5-HT Receptor |
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist. | |||
T26085 | Rilapine | Rilapinum | |
Rilapine is an atypical antipsychotic with high affinity for the 5-HT6 receptor. | |||
T24797 | SK609 HCl | SK-609 HCl,SK609 hydrochloride,SK 609 HCl,SK 609 hydrochloride,SK-609 hydrochloride | |
SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties. | |||
T83648 | Tenilapine | Others | |
Tenilapine is a neuroleptic compound that can be used to study atypical antipsychotics. | |||
T1567 | Olanzapine | LY170053 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR |
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness. | |||
T1211 | Levosulpiride | RV-12309,S-(-)-Sulpiride | Dopamine Receptor |
Levosulpiride (S-(-)-Sulpiride) is the (S)-enantiomer of sulpiride, which is a D2 receptor antagonist, an atypical antipsychotic drug of the benzamide class. | |||
T68081 | Girisopam | ||
Girisopam is a novel selective benzodiazepine analog for the 2,3-benzodiazepine binding site, an atypical psychoanalytic with anxiolytic effects. | |||
T0351 | Risperidone | Risperidal,R 64 766 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , P-gp |
Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent. | |||
T6241 | Quetiapine hemifumarate | Quetiapine Fumarate,ICI-204636 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression. | |||
T10249 | Adoprazine | SLV313 | Others |
Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties. | |||
T1025 | Tranylcypromine (2-PCPA) hydrochloride | Tranylcypromine (2-PCPA) HCl,SKF-385 HCl | Histone Demethylase , MAO |
Tranylcypromine (2-PCPA) hydrochloride (SKF-385 HCl), a Monoamine Oxidase inhibitor, is effective in the treatment of major depression, dysthymic disorder, and atypical depression. | |||
T23854 | Carbidine | Carbidine dihydrochloride,Karbidin,Carbidin,Karbidine | Others |
Carbidine (Carbidin) is a derivative of gamma-carboline, an atypical antipsychotic drug. It reduces the inhibitory effect of DA on the 3H-DA release from synaptosomes of the nucleus accumbens septi and on the activity of... | |||
T26543 | AC-90179 HCl | AC 90179,AC-90179 hydrochloride,AC90179,AC-90179 | 5-HT Receptor |
AC-90179 HCl (AC-90179 hydrochloride) is a selective inverse agonist of 5-HT2A receptor. AC-90179 HCl is an atypical antipsychotic pharmaceutical and has been shown to alleviate hallucinogen-induced vasocontriction. | |||
T10888 | CRT0066854 hydrochloride | ROCK , PKC | |
CRT0066854 hydrochloride is an effective selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively. |