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Adoprazine

Catalog No. T10249   CAS 222551-17-9
Synonyms: SLV313

Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.

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Adoprazine Chemical Structure
Adoprazine, CAS 222551-17-9
Pack Size Availability Price/USD Quantity
1 mg In stock $ 80.00
2 mg In stock $ 118.00
5 mg In stock $ 197.00
10 mg In stock $ 337.00
25 mg In stock $ 589.00
50 mg In stock $ 839.00
100 mg In stock $ 1,160.00
1 mL * 10 mM (in DMSO) In stock $ 217.00
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Purity: 99.44%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.
Synonyms SLV313
Molecular Weight 405.46
Formula C24H24FN3O2
CAS No. 222551-17-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 45mg/mL (111mM), sonification is recommended.

TargetMolReferences and Literature

1. Auclair AL, Kleven MS, Barret-Grévoz C, Barreto M, Newman-Tancredi A, Depoortère R. Differences among conventional, atypical and novel putative D(2)/5-HT(1A) antipsychotics on catalepsy-associated behaviour in cynomolgus monkeys. Behav Brain Res. 2009 N 2. Lange JH, Reinders JH, Tolboom JT, Glennon JC, Coolen HK, Kruse CG.Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs. J Med Chem. 2007 Oct 18;50(21):5103-8. 3. McCreary AC, Glennon JC, Ashby CR Jr, Meltzer HY, Li Z, Reinders JH, Hesselink MB, Long SK, Herremans AH, van Stuivenberg H, Feenstra RW, Kruse CG. SLV313 (1-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-4- [5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine monoh 4. Feenstra RW, van den Hoogenband A, Stroomer CN, van Stuivenberg HH, Tulp MT, Long SK, van der Heyden JA, Kruse CG. SAR study of 1-aryl-4-(phenylarylmethyl)piperazines as ligands for both dopamine D2 and serotonin 5-HT1A receptors showing varying degrees 5. Cosi C, Carilla-Durand E, Assié MB, Ormiere AM, Maraval M, Leduc N, Newman-Tancredi A. Partial agonist properties of the antipsychotics SSR181507, aripiprazole and bifeprunox at dopamine D2 receptors: G protein activation and prolactin release. Eur J Ph

Related compound libraries

This product is contained In the following compound libraries:
Clinical Compound Library Bioactive Compound Library Drug Repurposing Compound Library ReFRAME Related Library Antidepressant Compound Library Bioactive Compounds Library Max

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Adoprazine 222551-17-9 Others SLV 313 SLV313 SLV-313 inhibitor inhibit

 

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