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Search Results for " anti-leishmanial "

12

Compounds

Cat No. Product Name Synonyms Targets
TN4660 Niranthin Anti-infection , HBV , PAFR , Topoisomerase
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. N...
T0692 Allopurinol Zyloric,Zyloprim,Lopurin ROS , Xanthine Oxidase
Allopurinol (Zyloric) is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a Xanthine Oxidase Inhibitor.
T6376 Allopurinol Sodium Allopurinol sodium salt,Sodium allopurinol ROS
Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.
TN1432 Bacopasaponin C Anti-infection , GABA Receptor , NMDAR
Bacopasaponin C may have antioxidant activity, it also shows anti-leishmanial property.
T2P2806 Hederacolchiside A1 Raddeanoside R13 Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...
TN3729 Cuniloside B Antifection
Cuniloside B shows anti-leishmanial activity.
TN4470 Lyoniside Antifection
Lyoniside and saracoside are cytotoxic to promastigotes and intracellular amastigotes, they demonstrate strong anti-leishmanial efficacies in BALB/c mice model of leishmaniasis, suggests that these two compounds potentia...
T62574 Antileishmanial agent-6
Antileishmanial agent-6 is a potent anti-leishmanial agent with anti-leishmanial activity (IC50: 0.54 μM) and cytotoxicity (IC50: 10.2 μM) against Leishmania donovani and L-6.
TN1409 Asimilobine AChR , Antifection
(-)-Asimilobine shows antioxidative, anti-acetylcholinesterase (AChE), anti-α±-glucosidase, anti-leishmanial and anti-fungal activities; it displays weak inhibition against Streptococcus mutans (ATCC 25175), with a minim...
T62330 Antileishmanial agent-12
Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent with antibacterial activity against Leishmania brazilensis (IC50: 14.9 μM), Leishmania infantum (IC50: 21.3 μM) and T. cruzi (IC50. 9.3 μM). 9.3 μ...
T78973 DCN-83 Parasite
DCN-83, a potent anti-leishmanial compound, exhibits its highest efficacy against the amastigote form, achieving an IC50 value of 0.71 μM. It also possesses the ability to permeate the blood-brain barrier, impacting the ...
T76070 Defensin HNP-1 human TFA
Defensin HNP-1 Human TFA, a human neutrophil peptide (HNP), plays a role in the early development of atherosclerosis by contributing to endothelial cell dysfunction. Additionally, it has demonstrated broad-spectrum antim...
TargetMol