veratrum — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3363	Jervine	Iervin,11-Ketocyclopamine,Jerwiny	Hedgehog/Smoothened , Smo
	The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signa...		Hedgehog/Smoothened , Smo
TN1057	Veratrosine	Veratramine 3-glycoside,Veratramine-beta-D-glucoside	Platelet aggregation
	Veratrosine (Veratramine-beta-D-glucoside) is an alkaloid isolated from the herbs of Veratrum nigrum. Veratrosine exhibits feeble inhibition activity against platelet aggregation.		Platelet aggregation
TN2343	Pseudojervine	Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine	Platelet aggregation
	Pseudojervine (O-beta-D-Glucopyranosyljervine) is derived from Veratrum nigrum L. Pseudojervine exhibits feeble inhibition activity against platelet aggregation.		Platelet aggregation
T82009	Jervinone
	Jervinone, an alkaloid metabolite derived from Veratrum, is isolated from the mold Cunninghamella echinulata [1].
T39854	Cycloposine
	Cycloposine, a steroidal alkaloid present in the roots and rhizomes of Veratrum californicum, is known to possess teratogenic properties.
T82262	Grandivine A
	Grandivine A, a steroid alkaloid, has been isolated from Veratrum grandiflorum [1].
T34797	Teinemine	Muldamine,Deacetylmuldame,Deacetylmuldamine
	Teinemine also known as Muldamine, is a phytosterol alkaloid isolated from Veratrum californicum. It is the acetate ester of the piperidine steroid teinemine.
T0568	3,4-Dimethoxyphenylacetic acid	Homoveratrumic acid,homoveratric acid	Others , Endogenous Metabolite
	3,4-Dimethoxyphenylacetic acid (Homoveratrumic acid) is the papaverine intermediate, used to synthesis cardiovascular drugs.		Others , Endogenous Metabolite
T2173	Veratridine		Sodium Channel
	Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal.		Sodium Channel
T3363L	Jervine HCl	Jervine hydrochloride
	Jervine is a naturally occurring steroidal alkaloid derived from the Veratrum plant species. Over the Hedgehog signaling pathway, Jervine effectively inhibits tumor growth using three human tumor xenograft models. Jervin...
T3S1068	Oxyresveratrol	trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene	Tyrosinase , Autophagy , HSV
	1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxid...		Tyrosinase , Autophagy , HSV
T3744	Veratric acid	Veratrumenoic acid,3,4-Dimethoxybenzoic acid	Reactive Oxygen Species , COX
	Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-lowering effects.		Reactive Oxygen Species , COX
T78058	Verazine	(-)-Verazine
	(-)-Verazine is an antifungal agent isolated from the dried roots and rhizome of Veratrum maackii Regel, which induces DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. It has applicati...
T1558	Resveratrol	trans-Resveratrol,SRT 501	Apoptosis , Mitophagy , IκB/IKK , Lipoxygenase , Sirtuin , COX , NADPH , DNA/RNA Synthesis , Nrf2 , Antibacterial , Antibiotic , Autophagy , Antifungal
	Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autop...