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Search Results for " ufo "

Targets

19

Compounds

17

Natural Products

11

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T15390 Glufosfamide D 19575,Glucosylifosfamide mustard Others
Glufosfamide is a novel oxazolophosphamide compound with anticancer activity for the study of advanced non-small cell lung cancer.
T15391 Glufosinate ammonium Others
Glufosinate ammonium is a phosphinic acid analog of glutamic acid and an herbicide with neurotoxic activity. It is converted by plant cells into PT (L-phosphinothricin).
T20029 Buformin hydrochloride NSC528218,NSC-528218,NSC 528218 AMPK
Buformin hydrochloride (NSC-528218) is a potent AMPK activator,an oral antidiabetic drug of the biguanide class. Buformin delays the absorption of glucose from the gastrointestinal tract increases insulin sensitivity and...
T68146 Sufotidine AH 25352X,AH25352X,AH-25352X Histamine Receptor
Sufotidine (AH 25352X) is a highly selective competitive H2 receptor antagonist.
T31224 Piflufolastat DCFPYL Epigenetic Reader Domain
Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA. It is a fluorinated prostate-specific membrane antigen (PSMA) preparation. Piflufolastat can be used to prepare piflufolastat F 18 (DCFPyL F-18).
T131542 Arenobufagin (Arenobufogenin)
Arenobufagin (Arenobufogenin) is a useful organic compound for research related to life sciences and the catalog number is T131542.
T20772 Crufomate Ruelene,M 1261,M1261,Crufomatum,M-1261
Crufomate, an insecticide, is used extensively for the control of hornflies, cattle grubs and cattle lice.
T75992 Buforin II
Buforin II, a powerful antimicrobial peptide originating from Buforin I (a protein extracted from the Asian toad Bufo bufo gargarizans's stomach), exhibits broad-spectrum antimicrobial properties against both Gram-positi...
T15391L Glufosinate Others
Glufosinate, a phosphinic acid analog of glutamic acid, is a herbicide that is converted by plant cells into PT (L-phosphinothricin). It has neurotoxic activity.
T131543 Gamabufotalin (Gamabufagin; Gamabufogenin)
Gamabufotalin (Gamabufagin; Gamabufogenin) is a useful organic compound for research related to life sciences and the catalog number is T131543.
T30610 Bufotoxin Vulgarobufotoxin
Bufotoxin, a toxic steroid lactone, exists in the parotoid glands, skin, and poison of many toads and other amphibians, and in some plants and mushrooms.
T10116 3-O-Acetylbufotalin Others
3-O-Acetylbufotalin is a derivate of bufadienolide with anti-cancer activity.
T23837 Buformin W37,W 37,H 224,W-37
Buformin (1-butylbiguanide) is an oral antidiabetic drug of the biguanide class. It also inhibits the synthesis of glucose by the liver. Buformin delays absorption of glucose from the gastrointestinal tract increases ins...
T32590 Lauformine
Lauformine is a isoquinoline alkaloid.
T125720 Ajuforrestin A
Ajuforrestin A is a useful organic compound for research related to life sciences and the catalog number is T125720.
T27146 Denufosol tetrasodium INS37217,INS 37217,INS-37217
Denufosol is a P2Y2 agonist potentially for the treatment of cystic fibrosis.
T61011 Izuforant
Izuforant (JW1601) (Compound 24) has potent anti-inflammatory and anti-pruritic activities. Izuforant has a binding affinity for human serotonin 3 receptor (h5-HT3R) with an IC50 value of 9.1 μM. Izuforant is also an ora...
T124283 5beta-Hydroxybufotalin
5beta-Hydroxybufotalin is a useful organic compound for research related to life sciences and the catalog number is T124283.
T76864 Enapotamab TAM Receptor
Enapotamab is an AXL/UFO-related antibody that can be used to synthesize antibody-drug couplings (Enapotamab Vedotin).
Cat No. Product Name Synonyms Targets
T4A2458 Resibufogenin Bufogenin,Recibufogenin Others
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff...
T4A2399 Cinobufotalin IL Receptor , Akt , MRP , P-gp
Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent...
TN7062L Bufotenidine hydrochloride(487-91-2 Free base)
Bufotenidine hydrochloride(487-91-2 Free base) is a natural product for research related to life sciences. The catalog number is TN7062L and the CAS number is 40581-89-3.
T4A2456 Gamabufotalin Gamabufagin COX
1. Gamabufotalin (Gamabufagin) , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect.
T5A2461 Bufotalin Bufotaline Apoptosis , Others , Reactive Oxygen Species
1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.
T5527 Anigorufone Antifection
Anigorufone is a phytoalexin, it shows striking antinematode activity. Anigorufone has shown inhibitory activity on the growth of the germinative tube of Fusarium oxysporum f. sp. cubense race 4.
T31876 Frangufoline
Frangufoline is a sedative 14-membered frangulanine-type cyclopeptide alkaloid.
TN3035 4'-Hydroxy-2-O-methylanigorufone Others
9-(4'-Hydroxyphenyl)-2-methoxyphenalen-1-one(4'-Hydroxy-2-O-methylanigorufone) is a phytoalexin. It shows a strong α-glucosidase inhibitory effect.
T82807 Bufospirostenin A
Bufospirostenin A represents the inaugural (spirostanol) compound isolated from an animal source.
TN1912 Marinobufogenin Marinobufagenin ATPase , EGFR
Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure.
TN2877 3,4-Dihydroxy-2-O-methylanigorufone Others
3,4-Dihydroxy-2-O-methylanigorufone is a natural product for research related to life sciences. The catalog number is TN2877 and the CAS number is 1392307-42-4.
T82808 Bufoserotonin C
Bufoserotonin C, an indole alkaloid derived from the traditional Chinese medicine Chansu, exhibits antitumor activity and demonstrates an IC50 value of 34.3 μM in A549 cells [1] [2].
TN1572 Desacetylcinobufotalin Others
Desacetylcinobufotalin has significant antitumor activity through induction apoptosis via mitochondria pathway, it also shows potent cytotoxic activities against HL-60 cell lines.
T83282 5β-Hydroxybufotalin
5β-Hydroxybufotalin (compound 6), a natural anticancer agent derived from the traditional Chinese medicine Ch'an Su [1], exhibits potent inhibitory effects on cancer cell proliferation.
TN4238 Hydroxyanigorufone Others
Hydroxyanigorufone is a natural product from Musa itinerans Cheesm.
TN1200 19-Oxocinobufotalin Others
19-Oxocinobufotalin 3-adipoylarginine ester shows significant inhibition effect against human hepatocellular carcinoma cell line SMMC-7721 in vitro.
TN2787 2-O-Methylanigorufone Others
2-O-Methylanigorufone is a natural product from Monochoria vaginalis.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01601 AXL Protein, Human, Recombinant (His) Human HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPJ-00449 AXL Protein, Human, Recombinant (hFc) Human Human Cells
Axl, also known as Ufo and Ark, is a widely expressed 140 kDa glycoprotein in the TAM receptor tyrosine kinase family. Axl binds the vitamin K-dependent protein Gas6 which triggers tyrosine autophosphorylation of the Axl...
TMPJ-00399 AXL Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Axl, also known as Ufo and Ark, is a widely expressed 140 kDa glycoprotein in the TAM receptor tyrosine kinase family. Axl binds the vitamin K-dependent protein Gas6 which triggers tyrosine autophosphorylation of the Axl...
TMPY-01021 AXL Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPY-06478 AXL Protein, Human, Recombinant (mFc) Human HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPY-01364 AXL Protein, Mouse, Recombinant (His) Mouse HEK293
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip...
TMPK-00472 AXL Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-00407 AXL Protein, Human, Recombinant (His & Avi) Human HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-00408 AXL Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPK-00410 AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpre...
TMPJ-01081 Dtk Protein, Human, Recombinant (His) Human Human Cells
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs an...
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