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Search Results for " shik "

7

Compounds

16

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T126409 5-0-Galloylshikimicacid
5-0-Galloylshikimicacid is a useful organic compound for research related to life sciences. The catalog number is T126409 and the CAS number is 110082-91-2.
T125229 Yashabushiketol
Yashabushiketol is a useful organic compound for research related to life sciences. The catalog number is T125229 and the CAS number is 24192-00-5.
T125224 Shikokianin
Shikokianin is a useful organic compound for research related to life sciences and the catalog number is T125224.
T123852 3,5-Di-O-galloylshikimic acid
3,5-Di-O-galloylshikimic acid is a useful organic compound for research related to life sciences. The catalog number is T123852 and the CAS number is 95753-52-9.
T125228 Dihydroyashabushiketol
Dihydroyashabushiketol is a useful organic compound for research related to life sciences. The catalog number is T125228 and the CAS number is 24192-01-6.
T125535 3-O-Caffeoylshikimic acid
3-O-Caffeoylshikimic acid is a useful organic compound for research related to life sciences and the catalog number is T125535.
T123853 3,4-Di-o-galloylshikimicacid
3,4-Di-o-galloylshikimicacid is a useful organic compound for research related to life sciences. The catalog number is T123853 and the CAS number is 95753-51-8.
Cat No. Product Name Synonyms Targets
TN1440 Beta-Hydroxyisovalerylshikonin EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
TN1137 Isobutylshikonin Others
Isobutylshikonin exhibits obvious antioxidant activities , it exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·.
TN2447 Isovalerylshikonin Antibacterial
Isovalerylshikonin is a natural product from Arnebia euchroma
T5S2350 Beta-Acetoxyisovalerylshikonin Acetoxyisovalerylalkannin Others
Acetoxyisovalerylshikonin, a naphthoquinone derivative extracted from Arnebia euchroma, is a chemical compound.
TN1295 5-O-Caffeoylshikimic acid IL Receptor , TNF , NO Synthase
5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB.
T2897 (Rac)-Shikonin (±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid Others
(Rac)-Shikonin (Anchusin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics,...
T2739 Shikimic Acid Shikimate Others , Endogenous Metabolite
Shikimic Acid (Shikimate) is a tri-hydroxy cyclohexene carboxylic acid important in the biosynthesis of so many compounds that the shikimate pathway is named after it.
T5S2347 Deoxyshikonin Arnebin 7 Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial
1. Deoxyshikonin (Arnebin 7) may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) ...
T5S2343 Acetylshikonin Acetyl shikonin Others , P450 , AChE
1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...
T3S2344 β,β-Dimethylacrylshikonin Dimethylacrylshikonin,β, β-Dimethylacrylshikonin ERK , HIF/HIF Prolyl-Hydroxylase
1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...
T1125 Shikonin NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid TNF , NF-κB , Chloride channel , HIV Protease , PKM
Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.
TN1238 3,4-O-Isopropylidene-shikimic acid 3,4-O-Isopropylidene shikimic acid NOS , NO Synthase
3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by tri...
TN2207 Shikonofuran A Others
Shikonofuran A is a natural product isolated from Lithosperraum erythrorhizon Sieb.
TN6458 Acetylshikonin
Acetylshikonin can effectively inhibit tumor cells, it can be used to treat hepatocellular carcinoma cells expressing hepatitis B virus X protein (HBX) by inducing ER stress , an oncoprotein from hepatitis B virus. Acety...
TN2439 (2-Methylbutyryl)shikonin Others
(2-Methylbutyryl)shikonin is a natural product from Lithospermum erythrorhizon Sieb. et Zucc.
TN3052 4-O-Caffeoylshikimic acid Others
4-O-Caffeoylshikimic acid is a natural product from Illicium verum.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04466 STK40 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
STK40 is localized to both the cytoplasm and the nucleus. It is ubiquitously expressed. Mechanistically, Stk40 interacts with Rcn2, which also activates Erk1/2 to induce ExEn specification in mouse ESCs. Stk40 is able to...
TMPH-03584 Shikimate dehydrogenase Protein, S. epidermidis, Recombinant (His & Myc) Staphylococcus epidermidis E. coli
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). It can also u...
TargetMol