p11 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1879L1	P11 acetate		Integrin
	P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).		Integrin
TP2326L	Oligopeptide P11-4 acetate(593266-60-5 free base)		Others
	Oligopeptide P11-4 acetate is a peptide		Others
T34081	Piromelatine	NEU-P-11,NEU-P 11,NEU-P11	P2X Receptor , 5-HT Receptor , MT Receptor , Sodium Channel , TRP/TRPV Channel
	Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibitory effects on P2X3, TRPV1, and Nav1.7 channels, and can be ...
TP1879	HSDVHK-NH2	P11
	Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.
T24586	PAFAH1b2	PAFAH-1-b-2,3-IN-P11,3INP11,3 IN P11,PAFAH 1 b 2
	PAFAH1b2 is a selective platelet-activating factor acetylhydrolases 1b2 and 1b3 inhibitor that acts by impairing cancer cell survival.
T10922	CYP11B2-IN-1		P450
	CYP11B2-IN-1 is an effective and selective inhibitor of CYP11B2 with IC50s of 2.3 nM and 142 nM for CYP11B2 and CYP11B1.		P450
TP1947L	P110 TFA		Others
	P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity.		Others
T16422	P110δ-IN-1	PWT-143	PI3K
	P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).		PI3K
T3969	I-CBP112		Epigenetic Reader Domain , Histone Acetyltransferase
	I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.		Epigenetic Reader Domain , Histone Acetyltransferase
T4472	NMS-P118		PARP
	NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.		PARP
T24437	MCP110	MCP-110,MCP 110	Raf , Ras
	MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.		Raf , Ras
T7334	NP118809	39-1B4	Calcium Channel
	NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).		Calcium Channel
T9596	AP1189 acetate		Melanocortin Receptor
	AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.		Melanocortin Receptor
T4247	I-CBP112 hydrochloride		Epigenetic Reader Domain
	I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors. I-CBP112 (1 mM) has little activity against other bromodomains. I-CBP112 targets the CBP/p300 bromodomains. I-CBP112 significantly re...		Epigenetic Reader Domain
T64249	CYP11B1-IN-2
	CYP11B1-IN-2 (compound 7aa) is a selective, orally active inhibitor of CYP11B1 that acts on human CYP11B1 (IC50: 9 nM) and rat CYP11B1 (IC50: 25 nM). CYP11B1-IN-2 can be used to study diseases caused by cortisol overload...
T72397	PARP11 inhibitor ITK7	ITK7
	PARP11 Inhibitor ITK7 (ITK7) is a potent, selective inhibitor of PARP11, demonstrating significant efficacy with an IC50 value of 14 nM. It is primarily utilized in research focused on cellular localization.
T78033	SDP116
	SDP116, a synthetic peptide derivative of the GPR116 Stachel sequence, exhibits ADGRF5 agonistic activity [1].
T68254	WP1193
	WP1193 is an inhibitor of the JAK2/STAT3 pathway.
T38005	P11149
	P11149, a derivative of Galanthamine, acts as a competitive, orally active, and selective AChE inhibitor with the ability to weakly penetrate the blood-brain barrier (BBB). It demonstrates selective inhibition, exhibitin...
T78204	CYP11A1-IN-1
	CYP11A1-IN-1 (compound 30) is a selective inhibitor of the enzyme CYP11A1, displaying an IC50 ranging from 201-2000 nM. It is applicable in the study of steroid receptor-mediated diseases, specifically targeting the andr...