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Cat No. | Product Name | Synonyms | Targets |
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TP2419 | V-9-M Cholecystokinin nonapeptide | V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M | Beta Amyloid |
V-9-M Cholecystokinin nonapeptide (Prepro CCK Fragment V-9-M) is a precursor compound of cholecystokinin (CCK). Cholecystokinin (CCK) is a brain-intestinal peptide that stimulates gallbladder contraction and pancreatic e... | |||
TP2075L | Bombinakinin M acetate | Bombinakinin M acetate(509151-65-9 free base) | Bradykinin Receptor |
Bombinakinin M acetate is a potent bradykinin receptor agonist with high selectivity for mammalian arterial smooth muscle bradykinin receptors and is approximately 50 times more potent than bradykinin. | |||
T18226 | M-PEG9-CH2COOH | Others , PROTAC Linker | |
m-PEG9-CH2COOH is a PEG-based PROTAC linker. m-PEG9-CH2COOH can be used in the synthesis of PROTACs. | |||
T18223 | M-PEG9-acid | Others | |
m-PEG9-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system withi... | |||
T18224 | M-PEG9-Boc | Others | |
m-PEG9-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within... | |||
T18227 | M-PEG9-Hydrazide | Others | |
m-PEG9-Hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system ... | |||
T15940 | M-PEG9-Amine | Others | |
m-PEG9-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T18225 | M-PEG9-C4-SH | Others | |
m-PEG9-C4-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system with... | |||
T38647 | M-PEG9-Br | m-PEG9-Br | |
m-PEG9-Br is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within ... | |||
T38758 | M-PEG9-azide | m-PEG9-azide | |
m-PEG9-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system with... | |||
T15941 | M-PEG9-phosphonic acid | Others | |
m-PEG9-phosphonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome s... | |||
T18229 | M-PEG9-SH | Others , PROTAC Linker | |
m-PEG9-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within ... | |||
T15932 | M-PEG9-NHS ester | m-PEG8-CH2CH2-NHS ester | Others |
m-PEG8-CH2CH2-NHS ester is a PEG--based PROTAC linker can be used in the synthesis of PROTACs. | |||
T18228 | M-PEG9-phosphonic acid ethyl ester | Others | |
m-PEG9-phosphonic acid ethyl ester, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs[1]. | |||
T18439 | N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 | Others | |
N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 is a polyethylene glycol (PEG)-based PROTAC linker, specifically designed to aid in the synthesis of PROTACs[1]. | |||
T18438 | N-(m-PEG9)-N'-(PEG5-acid)-Cy5 | Others | |
N-(m-PEG9)-N'-(PEG5-acid)-Cy5 is a PEG-based PROTAC linker employed for the synthesis of PROTACs[1]. | |||
T65860 | (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(m-tolyl)propanoic acid | ||
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(m-tolyl)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65860 and the CAS number is 211637-74-0. | |||
T8756 | KRAS inhibitor-9 | DUN09716 | Apoptosis , Ras |
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS ... | |||
T16750 | Rigosertib | ON-01910 | Apoptosis , FLT , PLK , PI3K , Bcr-Abl , CDK , PDGFR , Src |
Rigosertib (ON-01910) is a selective and non-ATP-competitive inhibitor of PLK1 (IC50: 9 nM). Rigosertib is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition of the PI3 kina... | |||
T28449 | Pradefovir | ICN-2001-3,MB-6866,ICN-20013,MB-06866,Remofovir | HBV |
Pradefovir (Remofovir) is a reverse transcriptase inhibitor potentially for treatment of chronic HBV infection. Pradefovir is also a liver-targeted prodrug of adefovir. After metabolic activation, Pradefovir was converte... | |||
T5818 | Rigosertib sodium | Rigosertib,Estybon,ON-01910 | Apoptosis , PLK , PI3K |
Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3. | |||
T62567 | CDK2-IN-9 | ||
CDK2-IN-9 is a potent inhibitor of CDK2 (IC50: 0.63 μM) with anti-proliferative effects. CDK2-IN-9 is capable of blocking the cell cycle in S and G2/M phases and inducing apoptosis. CDK2-IN-9 has potential for melanoma r... | |||
T61935 | B-Raf IN 9 | ||
B-Raf IN 9 (compound 8b) is an effective B-Raf inhibitor (IC50=24.79 nM). B-Raf IN 9 blocks cell cycle at G2/M phase and induces apoptosis. B-Raf IN 9 showed potent anti-tumor activity on human prostate cancer PC-3 cells... | |||
T62217 | Tubulin polymerization-IN-9 | ||
Tubulin polymerization-IN-9 is a potent inhibitor of tubulin (IC50: 1.82 μM). Tubulin polymerization-IN-9 arrests the cell cycle of K562 cells in G2/M phase and induces apoptosis and mitochondrial depolarization. Tubulin... | |||
TP1350 | H-Val-Pro-Pro-OH TFA (58872-39-2 free base) | H-Val-Pro-Pro-OH TFA | |
H-Val-Pro-Pro-OH(TFA), a proline peptide derivative from milk, is an ACE inhibitor with IC50 of 9 M. | |||
T74621 | STING agonist-9 | ||
STING Agonist-9 (Compound 45) is a powerful stimulator of the STING pathway, demonstrating potent activity with an EC50 of 1.2 nM against human STING (h-STING) and 32.82 μM against mouse STING (m-STING). It exhibits anti... | |||
T63304 | Topoisomerase II inhibitor 9 | ||
Topoisomerase II inhibitor 9 is a Topo II inhibitor (IC50: 0.97 μM) and DNA embedding agent (IC50: 43.51 μM) that blocks the Hep G-2 cell cycle in the G2/M phase and induces apoptosis. | |||
T61779 | STAT3-IN-9 | ||
STAT3-IN-9, a potent inhibitor of STAT3 activation at Tyr705, exhibits no impact on the phosphorylation of STAT1 at Tyr 701. Additionally, this compound efficiently induces apoptosis and cell cycle arrest specifically at... | |||
TP1054 | PACAP (1-38), human, ovine, rat TFA | Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA) | |
PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP... | |||
T70527 | DAT-230 | ||
DAT-230 is a promising microtubule inhibitor that has great potential for the treatment of fibrosarcoma in vitro and in vivo. DAT-230 exhibited potent anti-proliferative activity against various cancer cells. DAT-230 -tr... | |||
T28092 | MPT0B206 | ||
MPT0B206 is a novel tubulin polymerization inhibitor. MPT0B206 induced G2/M cell cycle arrest and the appearance of the mitotic marker MPM-2 in K562 and K562R cells, which is associated with the upregulation of cyclin B1... | |||
T76041 | GIP (1-30) amide,human acetate | ||
GIP (1-30) amide, human acetate is a fragment of glucose-dependent insulinotropic polypeptide (GIP), an incretin hormone that plays a crucial role in stimulating insulin secretion and mitigating postprandial glycemic exc... | |||
T37713 | Funalenone | ||
Funalenone is a phenalenone originally isolated from A. niger. It inhibits HIV-1 integrase (IC50 = 10 μM) and HIV-1 replication in human peripheral blood cells transformed by murine leukemia virus (HPB-M(a); IC50 = 1.7 μ... | |||
T61673 | Anticancer agent 56 | ||
Anticancer agent 56 (compound 4d) is a powerful anti-cancer compound with favorable drug-like properties. It shows significant anticancer activity against multiple cancer cell lines, with an IC50 value of less than 3 μM.... | |||
TP1662 | Galanin Receptor Ligand M35 | ||
The chimeric peptide M35 [galanin (1-13)-bradykinin(2-9) amide] is a high-affinity galanin receptor ligand acting as a galanin receptor antagonist in the rat spinal cord, rat hippocampus and isolated mouse pancreatic isl... | |||
T35998 | 3,5-Dihydroxybenzaldehyde | ||
3,5-Dihydroxybenzaldehyde is a building block.1,2It has been used in the synthesis of 2,4-dimethylbenzoylhydrazones with antileishmanial and antioxidant activities. 1.Taha, M., Baharudin, M.S., Ismail, N.H., et al.Synthe... | |||
T71217 | MPT0B214 | ||
MPT0B214 is a novel and potent microtubule inhibitor with potential anticancer activity. MPT0B214 inhibited tubulin polymerization through strongly binding to the tubulin's colchicine-binding site and had cytotoxic activ... | |||
T36844 | Inostamycin A | ||
Inostamycin A is a bacterial metabolite that has been found inStreptomycesand has anticancer activity.1It is an inhibitor of CDP-diacylglycerol:inositol 3-phosphatidyltransferase (IC50= 0.02 μg/ml in A431 cell membranes)... | |||
T35423 | 7-oxo Staurosporine | ||
7-oxo Staurosporine is an antibiotic originally isolated from S. platensis with diverse biological activites. It inhibits PKC, PKA, phosphorylase kinase, EGFR, and c-Src in vitro (IC50s = 9, 26, 5, 200, and 800 nM, respe... | |||
T37002 | 7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (ammonium salt) | ||
7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (SBD-F) is a thiol-reactive fluorogenic probe.1It has been used to quantify the levels of homocysteine, cysteine, and cysteamine in human plasma.2SBD-F displays excitation/emissi... | |||
T37692 | Piericidin B | ||
Piericidin B is a bacterial metabolite that has been found inS. mobaraensisand has insecticidal and antimicrobial activities.1,2,3It inhibits NADH oxidase activity in isolated bovine heart mitochondria and inhibits respi... | |||
T37674 | Aspyrone | ||
Aspyrone is a polyketide fungal metabolite that has been found inAspergillusand has diverse biological activities.1,2It is active against a panel of 13 fungi when used at a concentration of 20 μg/ml and a panel of 21 bac... | |||
T37062 | L-Leucine-7-amido-4-methylcoumarin hydrochloride | ||
L-Leu-AMC is a fluorogenic substrate for leucine aminopeptidase.1Upon enzymatic cleavage by leucine aminopeptidase, AMC is released and its fluorescence can be used to quantify leucine aminopeptidase activity. AMC displa... | |||
T35504 | (±)10-HDHA | ||
(±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.[1][2] It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.[3][4][5] (±)10-HDHA is a potential marker of... | |||
T35975 | 6,9-Dichloro-1,2,3,4-tetrahydroacridine | ||
6,9-Dichloro-1,2,3,4-tetrahydroacridine is a synthetic intermediate in the synthesis of tacrine-based acetylcholinesterase (AChE) inhibitors.1It is also an intermediate in the synthesis of multifunctional tacrine hybrids... | |||
T35680 | 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide | ||
2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent.1It is active against the Gram-negative bacteriaE. coli,P. aeruginosa, andS. marcescens(MICs = 64, 100, and 70 μg/ml, respectively), the Gr... | |||
T36174 | Methyl 3,4-Dihydroxyphenylacetate | ||
Methyl 3,4-dihydroxyphenylacetate is a polyphenol that has been found inI. aquifoliumseeds and has antioxidant and antiviral activities.1,2It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50= 0... | |||
T36053 | D-Lysine lactam | ||
D-Lysine lactam is a chiral building block.1,2It has been used in the synthesis of a chiral antibiotic synthetic intermediate, as well as in the stereoselective synthesis of neurokinin (NK) receptor antagonists. 1.Kumar,... | |||
T37721 | Dihydronovobiocin | ||
Dihydronovobiocin is a coumarin antibiotic and derivative of novobiocin .1It is active against the bacteriaS. aureus,S. haemolyticus,D. pneumoniae,S. typhosa,K. pneumoniae, andP. multocida(MICs = 0.6, 2, 0.6, 10, 10, and... | |||
T35762 | MC1742 | ||
MC1742 is an inhibitor of class I histone deacetylases (HDACs; IC50s = 0.1, 0.11, 0.02, and 0.61 μM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 7 and 40 nM for HDAC6 and HDAC10, respectively).1 ... |
Cat No. | Product Name | Synonyms | Targets |
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T0062 | Folic acid | Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin | DNA/RNA Synthesis , Endogenous Metabolite |
Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis. | |||
T5S1952 | 9-Methoxycamptothecin | Apoptosis , Topoisomerase | |
9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition. | |||
TN5336 | 9-Oxo-10,11-dehydroageraphorone | 4,7(11)-Cadinadiene-3,8-dione,DTD,7,11-Dehydro-8-oxoageraphorone | |
9-Oxo-10,11-dehydroageraphorone has acaricidal activity. It induces hepatotoxicity and cholestasis in rats. 9-Oxo-10,11-dehydroageraphorone also effectively inhibits the proliferation of HeLa cells by arresting the cell ... | |||
T14121 | Actinonin | (-)-Actinonin | Aminopeptidase |
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin ... | |||
T37272 | 9(S),12(S),13(S)-TriHOME | ||
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble ... | |||
T36348 | Cerebroside C | ||
Cerebroside C is a fungal metabolite and glycosphingolipid that has been found in the rice pathogenic fungusM. grisea.1It induces production of the phytoalexin momilactone A when applied to wounded rice leaves, indicatin... |
Cat No. | Product Name | Species | Expression System |
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TMPY-03343 | EIF3K Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
EIF3K is a member of the eIF3 subunit K family. It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-... | |||
TMPJ-00865 | VEGF121 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD... | |||
TMPY-03698 | VEGF121b Protein, Human, Recombinant | Human | HEK293 Cells |
VEGF121b Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 34.10 kDa and the accession number is P15692-9. | |||
TMPH-00005 | YAP1 Protein, Human, Recombinant (Isoform 9, His) | Human | P. pastoris (Yeast) |
YAP1 Protein, Human, Recombinant (Isoform 9, His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 56.4 kDa; 80 kDa, reducing conditions and the accession number is P46937-9. | |||
TMPY-00818 | Granzyme H/GZMH Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Granzymes are key components of the immune response that play important roles in eliminating host cells infected by intracellular pathogens. Several granzymes are potent inducers of cell death. A total of eight granzymes... | |||
TMPH-02613 | ATF-5 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific respo... | |||
TMPK-00825 | VEGF121 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... | |||
TMPK-00826 | VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... | |||
TMPY-05268 | Neurofascin Protein, Human, Recombinant (hFc), Biotinylated | Human | HEK293 Cells |
Neurofascin Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 130 kDa and the accession number is O94856-9. |