Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSC-LC cells with KRAS mutation but not normal lung cells
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 55.00 | |
2 mg | In stock | $ 78.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 198.00 | |
25 mg | In stock | $ 372.00 | |
50 mg | In stock | $ 538.00 | |
100 mg | In stock | $ 690.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 146.00 |
Description | KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS inhibitor-9 selectively inhibits the proliferation of NSC-LC cells with KRAS mutation but not normal lung cells |
Synonyms | DUN09716 |
Molecular Weight | 292.81 |
Formula | C13H9ClN2S2 |
CAS No. | 300809-71-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 230 mg/mL (785.49 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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KRAS inhibitor-9 300809-71-6 Apoptosis GPCR/G Protein MAPK Ras non-small proliferation inhibit KRAS inhibitor 9 KRAS inhibitor9 DUN-09716 cytotoxicity cell H460 mutant H2122 H358 lung Inhibitor cancer cells DUN 09716 GTP-KRAS DUN09716 inhibitor