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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2344 | LY 344864 | LY344864 | 5-HT Receptor |
LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor. | |||
T16801 | (RS)-(Tetrazol-5-yl)glycine | LY 285265,D,L-(tetrazol-5-yl)glycine | NMDAR , iGluR |
(RS)-(Tetrazol-5-yl)glycine (LY 285265) (D,L-(tetrazol-5-yl)glycine) is an effective and selective N-methyl-D-aspartate receptor agonist. (RS)-(Tetrazol-5-yl)glycine has EC50s of 99 nM, 1.7 μM for GluN1/GluN2D, and GluN1... | |||
T0450 | Fluoxetine | LY-110140 | 5-HT Receptor , Serotonin Transporter , MRP , Autophagy |
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity. | |||
T4266 | LY334370 | LY 334370 | 5-HT Receptor |
LY334370 is a selective 5-HT1F receptor agonist with a Ki of 1.6 nM | |||
T1567 | Olanzapine | LY170053 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR |
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness. | |||
T1471 | Duloxetine hydrochloride | Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine |
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i... | |||
T9078 | LY3405105 | 1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester | CDK |
LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester) is a novel CDK7 inhibitors. | |||
T24423 | LY5 | LY 5,LY-5 | |
LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells. | |||
T4310 | Prexasertib | LY2606368 | Apoptosis , Chk |
Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity. | |||
T22948 | LY 272015 hydrochloride | Others | |
LY 272015 hydrochloride is a 5-HT2B receptor antagonist. | |||
T2344L | LY 344864 racemate | 5-HT Receptor | |
LY 344864 racemate is a 5-HT1F receptor agonist. | |||
T24421 | LY-2624803 | DB-7,LY2624803,HY-10275,LY 2624803 | 5-HT Receptor , Histamine Receptor |
LY-2624803 is a 5-HT2A receptor antagonist and histamine receptor inverse agonist that can be used to improve slow wave sleep. | |||
T22947 | LY266097 hydrochloride | LY 266097 hydrochloride | 5-HT Receptor |
LY266097 hydrochloride (LY 266097 hydrochloride) is an antagonist of 5-HT2 with pKis of 7.7, 9.8, and 7.6 for human 5-HT2A, 5-HT2B, and 5-HT2C and can be used in studies about depression. | |||
T27918 | LY 43578 | LY-43578,LY43578 | P450 , Aromatase |
LY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (IC50 of 0.3 and 5 μm, respectively) in rat liver microsomes.... | |||
T16977 | Talampanel | GYKI-53773,LY-300164 | Apoptosis , GluR |
Talampanel (LY-300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist with anti-seizure activity. Talampanel (IVAX) has neuroprotective effects in rodent stroke models. | |||
T27910 | LY 278584 | LY278584,LY-278584 | |
LY 278584 is an antagonist of 5-HT3-receptor. | |||
T27894 | LY 206130 | LY206130,LY-206130 | |
LY 206130 is an antagonist of serotonin 5-HT1A. | |||
T27955 | LY-426965 | LY 426965 | |
LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist. | |||
T27879 | LY 165163 | LY-165,163,LY165,163,LY 165,163 | |
LY-165163 is a selective antagonists of 5-HT1A and 5-HT1D serotonin receptor. | |||
T71374 | LY 178210 | ||
LY 178210 is a 5-hydroxytryptamine receptor agonist. |