il-3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8477	IQ-3		JNK
	IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α an...		JNK
T40127	IL-17 modulator 3
	IL-17 modulator 3 (US20200247785A1) is a chemical compound that acts as an IL-17 modulator. It has potential applications in researching inflammation, cancer, and autoimmune diseases.
T11636	IL-17A antagonist 3		IL Receptor
	IL-17A antagonist 3 is an IL-17A antagonist.		IL Receptor
T2893	Muscone	3-Methylcyclopentadecanone,Methylexaltone	MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin
	Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T9027	CA-4948	Emavusertib	IRAK , FLT
	CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.		IRAK , FLT
T4602	Hydrocortisone hemisuccinate	Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate	Glucocorticoid Receptor , Others , Interleukin
	Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.		Glucocorticoid Receptor , Others , Interleukin
T22698	TLR3-IN-1	CU CPT 4a	TLR
	TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cell...		TLR
T72549	IL-17A modulator-3
	IL-17A Modulator-3, an inhibitor of IL-17A/A, exhibits an IC 50 value of less than 10 μM. It is utilized in research related to inflammation, cancer, and autoimmune diseases.
T11670	IRAK inhibitor 3		IRAK
	IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.		IRAK
TN1787	Isomucronulatol 7-O-glucoside	Isomucronulatol 7-O-beta-glucoside	Others
	Isomucronulatol 7-O-glucoside is a natural product		Others
T38105	Ixekizumab	LY2439821	IL Receptor , Interleukin
	Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM.Ixekizumab blocks the binding of IL-17A to IL-17RA but not to other IL-17 ...		IL Receptor , Interleukin
T4S0795	Berberrubine chloride	9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline	IL Receptor
	1. Berberrubine chloride (9-Berberoline Chloride) has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expressio...		IL Receptor
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
TP2008L	Lyn peptide inhibitor acetate	Lyn peptide inhibitor acetate(222018-18-0 free base)	IL Receptor
	Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the bind...		IL Receptor
T5821	BC-1215		Others , Ligand for E3 Ligase
	BC-1215 is an inhibitor of F-box protein 3 (FBXO3, a ubiquitin E3 ligase component, IC50=0.9 μg/mL for IL-1β release).		Others , Ligand for E3 Ligase
T2061	APY0201		PI3K , Interleukin
	APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3, 5)P2.		PI3K , Interleukin
T7606	Guanosine 5'-diphosphate disodium salt	5'-GDP-Na2	Endogenous Metabolite
	Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway.		Endogenous Metabolite
T25150	BI-69A11	BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one	NF-κB , Akt
	BI-69A11 ((E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one) is a dual AKT and NFkB pathway inhibitor. It enhances the susceptibility of colon cancer cells to mda-7/IL-24-induce...		NF-κB , Akt
T76883	Talacotuzumab	CSL 362,JNJ 56022473	Immunology/Inflammation related , Interleukin
	Talacotuzumab (JNJ 56022473) is an IgG1 fully humanized CD123 neutralizing monoclonal antibody containing a modified Fc structure. Talacotuzumab has a high affinity for CD123, CD32b/c, CD16-158F and CD16-158V, with KD of...		Immunology/Inflammation related , Interleukin
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin