ikk — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6176	IKK 16	IKK Inhibitor VII,IKK-16,IKK16	IκB/IKK , LRRK2
	IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.		IκB/IKK , LRRK2
T40700	IKK-IN-3
	IKK-IN-3 is a highly potent and selective inhibitor of IkappaB kinase 2 (IKK2 or IKKβ). It exhibits impressive inhibitory activity against IKK2 (IC50 = 19 nM), while also demonstrating significant efficacy against IKK1 (...
T3094	PS-1145	IKK Inhibitor X	Apoptosis , IκB/IKK
	PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.		Apoptosis , IκB/IKK
T10237	ACHP Hydrochloride	IKK-2 Inhibitor VIII	IκB/IKK
	ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.		IκB/IKK
T15557	IKK 16 hydrochloride		Others
	IKK 16 hydrochloride is a selective IKK2, IKK complex, and IKK1 IκB kinase (IKK) inhibitor (IC50s: 40 nM, 70 nM and 200 nM, respectively). IKK16 inhibits leucine-rich repeat kinase-2 (LRRK2; IC50: 50 nM).		Others
T3384	Wedelolactone	IKK Inhibitor II	Apoptosis , NF-κB , Lipoxygenase , Caspase
	Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.		Apoptosis , NF-κB , Lipoxygenase , Caspase
T22021	ACHP	IKK-2 Inhibitor VIII	IκB/IKK
	ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-α and IKK-β. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR)-driven gene expression thro...		IκB/IKK
T11633	IKK-IN-1		IκB/IKK
	IKK-IN-1 is an inhibitor of IKK.		IκB/IKK
T6326	BMS-345541	BMS-345541 free base,IKK Inhibitor III,BMS345541	IκB/IKK
	BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.		IκB/IKK
T61059	IKK-IN-4
	IKK-IN-4 is a potent and selective inhibitor of IkappaB kinase 2 with IC 50 values of 45 and 650 nM against IKKβ and IKKα, respectively [1].
TQ0306	MLN120B		IκB/IKK
	MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).		IκB/IKK
T6771	AZD3264		IκB/IKK
	AZD3264 is a new type IKK2 inhibitor.		IκB/IKK
T5540	GSK8612		IκB/IKK
	GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .		IκB/IKK
T2279	Tizoxanide	Desacetyl-nitazoxanide,TIZ	Antiviral , HIV Protease , Antibacterial , Autophagy
	Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).		Antiviral , HIV Protease , Antibacterial , Autophagy
T7951	TBK1/IKKε-IN-5		IκB/IKK
	TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).		IκB/IKK
T15564	IMD-0560		IκB/IKK
	IMD-0560 is a novel inhibitor of IκB kinase β.		IκB/IKK
T5209	INH14		IκB/IKK
	INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).		IκB/IKK
T1830	BX795		IκB/IKK , Chk , CDK , c-Kit , PDK , Autophagy
	BX795 is an effective and selective PDK1 inhibitor (IC50: 6 nM), and its selectivity is 140- and 1600-fold for PDK1 over PKA and PKC in cell-free assays, respectively. Meanwhile, the selectivity for PDK1 is 100-fold than...		IκB/IKK , Chk , CDK , c-Kit , PDK , Autophagy
T15559	TBK1/IKKε-IN-2		IκB/IKK
	TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.		IκB/IKK
T5796	Plantainoside D	Isoplantamajoside	RAAS , PKC
	Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitro with the IC(50) value of 2.17 mM, it ...		RAAS , PKC