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Cat No. | Product Name | Synonyms | Targets |
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T76792 | Sibrotuzumab | BIBH 1,Anti-Human FAP Recombinant Antibody | Others |
Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targeting Fibroblast Activating Protein (FAP).Sibrotuzumab is used in the study of colorectal cancer and non-small cell lung cancer. | |||
T74402 | FAP-PI3KI1 | ||
FAP-PI3KI1, a fibroblast-activated protein (FAP)-targeted PI3K inhibitor, selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells. It effectively inhibits collagen synthesis and reduces collage... | |||
T74547 | FAP-2286 acetate | ||
FAP-2286 acetate, a conjugate of a fibroblast activation protein (FAP)-binding peptide, exhibits antitumor activity [1]. It can be labeled with radionuclides for diagnostic purposes. | |||
T74546 | FAP-2286 | ||
FAP-2286 is a peptidic macrocycle that binds to the fibroblast activation protein (FAP) and is linked to the chelator DOTA, facilitating its role as a tumor imaging agent in positron emission tomography (PET) research. E... | |||
T82417 | FAP Ligand 1 | ||
FAP Ligand 1 (FL), a high-affinity small molecule targeting fibroblast activation protein (FAP), facilitates the delivery of conjugated therapeutics to FAP-expressing fibroblasts and enables radiographic imaging of selec... | |||
T79917 | FAP-IN-2 | ||
FAP-IN-2 is a 99mTc-labeled, isonitrile-containing derivative of a fibroblast activation protein (FAPI) inhibitor suitable for tumor imaging [1]. | |||
T78921 | FAP-IN-1 | ||
FAP-IN-1 is a fibroblast activation protein (FAP) inhibitor, exhibiting an IC50 of 3.3 nM, and is utilized for cancer research [1]. | |||
T78214 | FAP-IN-2 TFA | ||
FAP-IN-2 TFA is a 99mTc-labeled, isonitrile-containing derivative inhibitor of fibroblast activation protein (FAP), utilized for tumor imaging [1]. | |||
T9855 | BR102910 | 4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]- | Others |
BR102910 (4-Thiazolecarboxamide, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-2-[(3,4-dichlorophenyl)methyl]-) is a selective inhibitor of fibroblast activated protein (FAP). | |||
T26235 | Sulfaperin | Methylsulfadiazin,Archisulfa,Chemiopen,Demosulfan,Anastaf,Isosulfamerazine | Antibacterial |
Sulfaperin (Chemiopen) is a sulfonamide antibacterial agent. | |||
T13033 | Sulfaproxiline | Sulfaproxyline,Sulphaproxyline,Sulfaproxylin | Antibacterial |
Sulfaproxiline (Sulfaproxylin) is a synthetic antibacterial drug of sulfonamide. | |||
T4567 | Sulfaphenazole | Plisulfan,Raziosulfa,Depocid,Depotsulfonamide | P450 , Antibacterial |
Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1... | |||
T0767 | Sulfapyridine | Sulfidine,Sulfidin,2-Sulfapyridine | Antibacterial , Antibiotic , Autophagy |
Sulfapyridine (2-Sulfapyridine) is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine. | |||
T5099 | Gefapixant | RO 4926219,AF219,MK-7264 | P2X Receptor |
Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. | |||
T6482 | Efaproxiral Sodium | RSR13 sodium | Reactive Oxygen Species |
Efaproxiral Sodium (RSR13 sodium), a synthetic allosteric modifier of hemoglobin, is utilized for brain metastases originating from breast cancer. | |||
T1629 | Rifapentine | MDL473,Rifapentina,Rifapentinum,DL 473,Priftin,Cyclopentylrifampicin | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections. | |||
T78667 | FAPI-74 | ||
FAPI-74 serves as a positron emission tomography (PET) tracer specifically targeting fibroblast activation protein (FAP), utilized in the study of FAP-positive tumors [1]. | |||
T69660 | NOTA-FAPI-4 | ||
NOTA-FAPI-4 is an analogue of FAPI-4 and a fibroblast activation protein (FAP) inhibitor. NOTA-FAPI-4 is useful in the diagnosis or treatment of a disease characterized by overexpression of fibroblast activation protein... | |||
T11264 | FAPI-4 | Others | |
Api-4 is a fibroblast activated protein (FAP) inhibitor used in cancer research. | |||
T39922 | FAPI-46 | ||
FAPI-46 is a quinoline-derived radiotracer that specifically targets fibroblast activation protein (FAP). It exhibits enhanced tumor uptake and extended accumulation in tumor tissues, rendering it suitable for diverse ca... | |||
T35852 | FAPI-34 | ||
FAPI-34, a fibroblast-activating protein (FAP) inhibitor, boasts advantageous pharmacokinetic and biochemical attributes. | |||
T82416 | FAPI-2 TFA | ||
FAPI-2 TFA is a fibroblast activation protein (FAP) inhibitor, potentially applicable in cancer research. [1] | |||
T62879 | OncoFAP | ||
OncoFAP is an ultra-high affinity fibroblast activating protein (FAP) ligand with potential tumour targeting. | |||
T11263 | FAPI-2 | Others | |
Fapi-2 is a fibroblast activated protein (FAP) inhibitor used in cancer research. | |||
T21318 | Efaproxiral | RSR13,Efaproxyn,RSR 13,RSR-13 | |
Efaproxiral is a synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen... | |||
T63846 | Gefapixant citrate | ||
Gefapixant citrate is an orally active P2X3 receptor (P2X3R) antagonist that acts on human homologous recombinant hP2X3 (IC50: ~30 nM) and hP2X2/3 (IC50: 100-200 nM). gefapixant citrate can be used to study chronic cough... | |||
T13034 | Sulfapyridine-d4 | Others | |
Sulfapyridine D4 a deuterium labeled Sulfapyridine. Sulfapyridine is a agent of sulfonamide antibacterial. | |||
TMIH-0250 | Gefapixant-d3 | ||
Gefapixant-d3 is a deuterated compound of Gefapixant. Gefapixant has a CAS number of 1015787-98-0. Gefapixant is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at h... | |||
T25221 | Cefaparole | Cefaparol,Lilly 110264,Lilly-110264,Lilly110264,Cefaparolum | |
Cefaparole is an antibacterial compound and cell wall biosynthesis inhibitor. | |||
T26331 | Wofapyrin | Rheopyrine,Reopin G | |
Wofapyrin is an antipyretic and antiphlogistic. | |||
T29330 | 25-Desacetylrifapentine | L14583,L-14583 | |
25-Desacetylrifapentine is the main metabolite of DL 473-IT in plasma. | |||
T29860 | Alfaprostol | ||
Alfaprostol is a bioactive chemical. | |||
T82502 | Efaprinermin alfa | OMP-336B11 | |
Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody that targets TNFRSF18, and functions as a GITR ligand-Fc fusion protein [1]. | |||
T7890 | SP-13786 | UAMC-1110 | Others |
SP-13786 (UAMC-1110) is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 μM). | |||
T21724L | Fas C-Terminal Tripeptide Acetate | Fas C-Terminal Tripeptide Acetate (189109-90-8 free base) | Others , Fatty Acid Synthase |
Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding. | |||
T26658 | ARI-3099 HCl | ARI-3099,ARI3099,ARI 3099 | |
ARI-3099 inhibits fibroblast activation protein, alpha (FAP). | |||
T74482 | Suc-Gly-Pro-AMC | ||
Suc-Gly-Pro-AMC, a fibroblast activation protein (FAP)-specific substrate, facilitates the examination of FAP activity [1]. | |||
T10227 | Ac-Gly-BoroPro | Others | |
Ac-Gly-BoroPro is a selective FAP inhibitor (Ki: 23 nM). | |||
T74500 | FSDD3I | ||
FSDD3I, an albumin-binding fibroblast activation protein (FAP) ligand, can be tagged with isotopes 68Ga and 177Lu for use in single photon emission computed tomography (SPECT) imaging [1]. | |||
T77169 | Simlukafusp alfa | ||
Simlukafusp alfa (FAP-IL2v) is an immunocytokine that consists of an antibody targeting fibroblast activation protein α (FAPα) linked to a variant of IL-2, which specifically interacts with IL-2Rβγ. The compound is of th... | |||
T69603 | BR103354 | ||
BR103354 is a novel fibroblast activation protein (FAP) inhibitor with anti-diabetic and anti-steatotic effects. BR103354 inhibited FAP with an IC50 value of 14 nM, showing high selectivity against dipeptidyl peptidase (... | |||
T38406 | L-Proline 4-methoxy-β-naphthylamide hydrochloride | H-Pro-4MβNA hydrochloride,L-Proline 4-methoxy-β-naphthylamide hydrochloride | |
L-Proline 4-methoxy-β-naphthylamide hydrochloride, also known as H-Pro-4MβNA hydrochloride, is a chemical compound utilized in the preparation of Fap-activated anti-tumor compounds. | |||
T74648 | TAM470 | ||
TAM470, a novel cytolysin, inhibits both tubulin polymerization and microtubule depolymerization. It serves as a precursor in the synthesis of OMTX705, a payload molecule. OMTX705 represents a new class of FAP-targeting ... | |||
T74498 | FSDD0I | ||
FSDD0I, an albumin-binding fibroblast activation protein (FAP) ligand, can be labeled with 68Ga and 177Lu for use in single photon emission computed tomography (SPECT) imaging [1]. | |||
T74499 | FSDD1I | ||
FSDD1I, an albumin-binding fibroblast activation protein (FAP) ligand, can be tagged with 68 Ga and 177 Lu for use in single photon emission computed tomography (SPECT) imaging [1]. | |||
T77863 | TAM558 | ||
TAM558 is a payload molecule utilized in the synthesis of OMTX705, which is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470, exhibiting antitumor activity [1]. | |||
T78179 | NH2-UAMC1110 TFA | ||
NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating agent crucial for creating radiotracers with high tumor selecti... | |||
T37861 | Talabostat | ||
Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4643 | TFAP | N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide | COX , Endogenous Metabolite |
TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor | |||
T19320 | FAPy-adenine | Others | |
FAPy-adenine is an oxidized DNA base.Adenine is on the rise in the brains of people with Alzheimer's disease.Nucleoside oxidation is a biochemical marker for tumors, senescence and neurodegenerative diseases. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00373 | FAP Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i... | |||
TMPY-02154 | FAP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1. | |||
TMPY-04962 | FAP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
FAP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is A0A2K5VGF4. | |||
TMPK-00923 | FAP Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i... | |||
TMPK-01282 | FAP Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated | Cynomolgus | HEK293 Cells |
Fibroblast activation protein (FAP) is a serine protease that has been reported in fibroblasts and some carcinoma cells, which correlates with poor patient outcomes. FAP can be induced under hypoxia which is also vital i... | |||
TMPY-04922 | FAP Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1. | |||
TMPY-06915 | FAP Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 88.23 kDa and the accession number is Q12884-1. | |||
TMPY-06525 | FAP Protein, Human, Recombinant (aa 27-760, His) | Human | Baculovirus Insect Cells |
FAP Protein, Human, Recombinant (aa 27-760, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 86.31 kDa and the accession number is Q12884-1. | |||
TMPY-04171 | MFAP3 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
MFAP3 (Microfibril Associated Protein 3) is a Protein Coding gene. The human gene encoding MFAP3 has a very simple structure, containing only two translated exons encoding a protein of 362 amino acids. The gene was found... | |||
TMPH-02673 | GFAP Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. | |||
TMPJ-00846 | GFAP Protein, Human, Recombinant (His) | Human | E. coli |
Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal c... | |||
TMPY-03052 | MFAP5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MFAP5 (Microfibril Associated Protein 5, also known as MAGP2) is a Protein Coding gene. MFAP5 is a component of the elastin-associated microfibrils. It belongs to the MFAP family. As a 25-kD microfibril-associated glycop... | |||
TMPK-00957 | MFAP5 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-assoc... | |||
TMPH-00465 | GFAP Protein, Danio rerio, Recombinant (His & Myc & SUMO) | Danio rerio (Zebrafish) | E. coli |
N/A. GFAP Protein, Danio rerio, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 71.2 kDa and the accession number is Q58EE9. | |||
TMPK-01159 | MFAP4 Protein, Mouse, Recombinant (His & Flag) | Mouse | HEK293 Cells |
MFAP4 Protein, Mouse, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 28.7 kDa and the accession number is Q9D1H9-1. | |||
TMPH-02674 | GFAP Protein, Mouse, Recombinant | Mouse | Baculovirus Insect Cells |
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. | |||
TMPJ-00566 | MFAP4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Microfibril-associated glycoprotein 4(MFAP4) is a secreted protein and contains 1 fibrinogen C-terminal domain, similarity to a bovine microfibril-associated protein. The protein has binding specificities for both collag... | |||
TMPK-00477 | MFAP4 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
MFAP4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 27.60 kDa and the accession number is A0A2K5TQS8. | |||
TMPY-02949 | AP2 Gamma/TFAP2C Protein, Human, Recombinant (His) | Human | E. coli |
TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of imp... | |||
TMPK-01217 | MFAP5 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-assoc... | |||
TMPK-00900 | MFAP4 Protein, Human, Recombinant (His & Flag) | Human | HEK293 Cells |
MFAP4 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 28.6 kDa and the accession number is P55083-1. | |||
TMPH-03279 | DPP4/CD26 Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, ... |