Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FAPy-adenine is an oxidized DNA base.Adenine is on the rise in the brains of people with Alzheimer's disease.Nucleoside oxidation is a biochemical marker for tumors, senescence and neurodegenerative diseases.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 35.00 | |
5 mg | 5 days | $ 54.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 89.00 |
Description | FAPy-adenine is an oxidized DNA base.Adenine is on the rise in the brains of people with Alzheimer's disease.Nucleoside oxidation is a biochemical marker for tumors, senescence and neurodegenerative diseases. |
In vitro | In the absence of the external field the FAPy-adenine is able to form pairs with all four canonical nucleic acid bases.?In contrast, in the presence of the external field the mispairing abilities of FAPy-adenine become insignificant since the most stable dimers are formed with thymine |
In vivo | Oxygen-derived radicals exacerbate nuclear DNA damage in Alzheimer's disease, reinforcing the notion that the brain endures heightened oxidative stress in this condition. |
Molecular Weight | 153.14 |
Formula | C5H7N5O |
CAS No. | 5122-36-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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FAPy-adenine 5122-36-1 Others FAPy adenine FAPyadenine inhibitor inhibit