Search Result

Search Results for " e6 "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T36466	Chlorin E6	Ce6,Chlorin e6,CE6	Parasite
	Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation. In a mouse model of implanted fibrosarcoma, Chlorin E6 (2.5-10 mg/kg, i.v., 50-200 J/cm2 irradiat...		Parasite
T40435	Chlorin e6 trimethyl ester
	Chlorin e6 trimethyl ester, a derivative of methyl pheophorbide-a, is an effective photosensitizer for photodynamic therapy (PDT).
T1254	Chlorophyllin sodium copper salt	Chlorophyllin copper sodium complex,Chlorophyllin,Chlorophyllin coppered trisodium salt,Sodium-copper chlorin e6	Others
	Chlorophyllin sodium copper salt (Chlorophyllin coppered trisodium salt) is a semi-synthetic mixture of water-soluble sodium copper salts derived from chlorophyll, primarily used as a food additive and alternative medici...		Others
T16978	Talaporfin sodium	ME2906,NPe6,Mono-L-aspartyl chlorin e6	Others
	Talaporfin is a photosensitizer used in photodynamic therapy.		Others
T60014	SHEN26		Antiviral
	SHEN26 has antiviral activity and can be used in research on the treatment of viral infections.		Antiviral
T0711	Niclosamide	BAY2353,Niclocide	Antibiotic , STAT , Parasite
	Niclosamide (Niclocide)(BAY2353) is used to treat most tapeworm infections by inhibiting DNA replication.		Antibiotic , STAT , Parasite
T1406	Amantadine hydrochloride	1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride	Dopamine Receptor , Influenza Virus
	Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.		Dopamine Receptor , Influenza Virus
T4068	E6446 dihydrochloride		TLR
	E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation of HEK:TLR9 cells with IC50 of 10 nM.		TLR
T4206	E6446		TLR
	E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to ...		TLR
T11141	E64FC26		Others
	E64FC26 is a potent protein disulfide isomerase (PDI) family pan-inhibitor with antitumor activity, inhibits PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6, and can be used in the study of multiple myeloma and pancreatic cancer.		Others
T31592	E6801	E 6801,E-6801	5-HT Receptor
	E6801 is a novel selective 5-HT6 receptor agonist with a wide range of biological activities.E6801 can be used in the study of dementia, Parkinson's disease, depression, obesity epilepsy, anxiety, and many other diseases...		5-HT Receptor
TP2103L	[D-p-Cl-Phe6,Leu17]-VIP acetate		Others
	[D-p-Cl-Phe6,Leu17]-VIP acetate is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor (IC50 = 125.8 nM).		Others
TF0029	Hexaethylene Glycol Monooctyl Ether (C8E6)
	Hexaethylene Glycol Monooctyl Ether (C8E6) is a useful organic compound for research related to life sciences. The catalog number is TF0029 and the CAS number is 4440-54-4.
T10555	BJE6-106	B106	PKC
	BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM). BJE6-106 induces caspase-dependent apoptosis with tumor-specific effect.		PKC
T36651	Anti-MERS-2E6 mAb	Anti-MERS-2E6 mAb
	Anti-MERS-2E6 mAb (MERS-2E6), a human IgG1 neutralizing antibody, is expressed in CHO cells. It effectively competes with the virus Spike protein for binding to the CD26 receptor, consequently inhibiting viral invasion i...
T76601	(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
	(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14), a bombesin (BBN) antagonist, holds potential for cancer research applications [1].
T83945	XIE62-1004
	XIE62-1004 is a chemical compound that induces the interaction between p62 and LC3 by binding to the ZZ domain of p62. This interaction promotes p62 self-aggregation and its subsequent interaction with LC3 on autophagoso...
TF0030	Hexaethylene Glycol Monodecyl Ether (C10E6)
	Hexaethylene Glycol Monodecyl Ether (C10E6) is a useful organic compound for research related to life sciences. The catalog number is TF0030 and the CAS number is 5168-89-8.
T61755	E6201
	E6201 (ER-806201) is a potent dual kinase inhibitor targeting MEK1 and FLT3, inhibiting their activities in an ATP-competitive manner. It effectively suppresses MEK1-induced ERK2 phosphorylation (IC50 = 5.2 nM), MKK4-ind...
T62678	YE6144
	YE6144 is a typical inhibitor of interferon regulatory factor 5 (IRF5), which inhibits IRF5 phosphorylation and thus selectively inhibits IRF5 activity.
T38774	E67-2	E67-2
	E67-2, a derivative of E67, is a low-toxicity, selective inhibitor of the KIAA1718 Jumonji domain. It has an IC 50 value of 3.4 μM. E67-2 specifically inhibits the Jumonji demethylase for histone H3 lysine 9 (H3K9) and h...
T78003	[D-p-Cl-Phe6,Leu17]-VIP TFA
	[D-p-Cl-Phe6,Leu17]-VIP TFA acts as a competitive and selective antagonist of the vasoactive intestinal peptide (VIP) receptor, exhibiting an IC50 of 125.8 nM. It shows no activity on glucagon, secretin, or growth hormon...
TF0071	Hexaethylene Glycol Monododecyl Ether (C12E6)
	Hexaethylene Glycol Monododecyl Ether (C12E6) is a useful organic compound for research related to life sciences. The catalog number is TF0071 and the CAS number is 3055-96-7.
T11140	E6130		CXCR
	E6130 may be effective in the treatment of inflammatory bowel disease and is a highly selective CX3CR1 regulator for oral administration.		CXCR
TP2103	[D-p-Cl-Phe6,Leu17]-VIP
	Selective vasoactive intestinal peptide (VIP) receptor antagonist (IC50 = 125.8 nM). Displays no activity on glucagon, secretin or GRF receptors.
T11442	GNE684		TNF
	GNE684 is a potent inhibitor of potent receptor interacting protein 1 (RIP1) with average Ki app values of 21 nM, 189 nM and 691 nM for human mouse and rat RIP1, respectively [1].		TNF
T39812	(E/Z)-E64FC26	(E/Z)-E64FC26
	(E/Z)-E64FC26 is a mixture complex comprising E-E64FC26 and Z-E64FC26. E-E64FC26 is a highly potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50 values of 1.9, 20.9, 25.9, 16.3, and 25.4 μM ag...
T33267	Me6TREN 4HCl	Me6TREN Tetrahydrochloride,Me6-TREN Tetrahydrochloride,Me6 4HCl,Me 6 4HCl,Me-6 4HCl
	Me6TREN 4HCl is a potent and efficacious mobilizing agent of hematopoietic stem and progenitor cells (HSPCs) that can act by activating MMP-9 expression and disrupting the SDF-1α/CXCR4 axis, exhibiting more significant m...
T70900	VT-ME6
	VT-ME6 is a potent and selective sphingosine kinase 2 inhibitor. VT-ME6, contained a quaternary ammonium group as a warhead and established that a positively charged moiety is necessary for engaging key amino acid residu...
T81254	RPE65-IN-1
	RPE65-IN-1 (Compound 16e) serves as a potent inhibitor of RPE65, applicable in studies related to retinopathy [1].
T17228	Sabizabulin	ABI-231,VERU-111	Microtubule Associated
	Sabizabulin (ABI-231) is an effective and orally bioavailable inhibitor of α and β tubulin against panels of melanoma and prostate cancer cell lines. Sabizabulin inhibits tumor growth and metastatic phenotypes of cervica...		Microtubule Associated
T37173	MPro Inhibitor 11a
	MProinhibitor 11a is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.053 μM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-i...
T1307	Carmofur	HCFU	Nucleoside Antimetabolite/Analog , Virus Protease , SARS-CoV , DNA/RNA Synthesis
	Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
T15172	DSHS00884	SSYA10-001	Others
	DSHS00884 is a potent inhibitor of human papillomavirus E6 (IC50: 10 μM).		Others
T28534	RH02007	CCG 40788,RH-02007,CCG40788,CCG-40788,RH 02007
	RH02007 is an inhibitor of the human papillomavirus (HPV) E6 oncoprotein.
T71941	Lig3
	Lig3 is an inhibitor against high-risk strains of human papillomavirus (HPV) E6 oncoprotein.
T40207	SARS-CoV-2-IN-7
	SARS-CoV-2-IN-7 demonstrates potent inhibition of viral replication in SARS-CoV-2-infected Vero E6 cells with an IC50 value of 844 nM.
T79329	SARS-CoV-2-IN-56		SARS-CoV
	SARS-CoV-2-IN-56 (Compound 63) is a SARS-CoV-2 inhibitor with antiviral activity, demonstrating inhibition of the virus in Vero E6 cells with an IC50 of 0.7 μM [1].		SARS-CoV
T79328	SARS-CoV-2-IN-54		SARS-CoV
	SARS-CoV-2-IN-54 (Compound 2), a SARS-CoV-2 inhibitor, exhibits antiviral activity by impeding the virus in Vero E6 cells with an inhibitory concentration (IC50) of 21.4 μM [1].		SARS-CoV
T81209	SARS-CoV-2-IN-62		SARS-CoV
	SARS-CoV-2-IN-62 (Compound R3b) effectively inhibits SARS-CoV-2 replication in Vero E6 and Calu-3 cells, demonstrating low cytotoxicity and EC50 values of 2.97 μM and 3.82 μM, respectively [1].		SARS-CoV
T72519	Niclosamide sodium	BAY2353 sodium
	Niclosamide sodium (BAY2353), an orally active antihelminthic agent employed in parasitic infection research, serves as a potent STAT3 inhibitor, demonstrating an IC50 of 0.25 μM in HeLa cells. Additionally, this compoun...
T79462	SARS-CoV-2 3CLpro-IN-14		SARS-CoV
	SARS-CoV-2 3CLpro-IN-14 (compound 11j) is an orally active inhibitor of SARS-CoV-2 3CLpro, demonstrating potent anti-SARS-CoV-2 properties with an EC50 of 0.18 μM and exhibits minimal cytotoxicity, having a CC50 greater ...		SARS-CoV
T81208	SARS-CoV-2-IN-63		SARS-CoV
	SARS-CoV-2-IN-63 (Compound R3e) serves as an inhibitor of SARS-CoV-2 replication, demonstrating low cytotoxicity. It effectively suppresses viral replication within Vero E6 cells and Calu-3 cells, yielding half-maximal e...		SARS-CoV
T79661	SARS-CoV-2 3CLpro-IN-18		SARS-CoV
	SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent inhibitor of SARS-CoV-2 3CLpro with an IC50 of 0.478 μM. It demonstrates inhibition of SARS-CoV-2 in Vero E6 cells, with an EC50 of 2.499 μM, and exhibits low cytotoxic...		SARS-CoV
T80686	γ-AA peptide P6
	γ-AA peptide P6 acts as a potent activator of E6 associated protein (E6AP), facilitating both its self-ubiquitination and the ubiquitination of E6AP substrates in vitro reconstituted reactions. Furthermore, γ-AA peptide ...
T36435	SP 10
	Peptide originally derived from SARS-CoV Spike (S) protein; corresponds to amino acid residues 668 to 679. Highly potent inhibitor of SARS-CoV S protein and ACE2 interaction (IC50 = 1.88 nM in biochemical assay). Inhibit...
T79455	SARS-CoV-2 Mpro-IN-9		SARS-CoV
	SARS-CoV-2 Mpro-IN-9 (compound c7), a nonpeptidic, noncovalent inhibitor of SARS-CoV-2 main protease (Mpro), exhibits potent inhibitory action (IC50 = 0.085 μM) and improved physicochemical and drug metabolism and pharma...		SARS-CoV
T37174	SARS-CoV MPro-IN-1
	MProinhibitor 11b is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.04 μM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-in...
T83947	HDAC4 CHDI Degrader 11
	HDAC4 CHDI Degrader 11 is a potent, selective degrader of HDAC4 (PROTAC) with DC_50 values of 4 nM and 6 nM in Jurkat E6-1 and Jurkat cells, respectively. This compound integrates the class IIa HDAC inhibitor trifluorome...

Compounds

Chlorin E6

T36466

Synonym: Ce6,Chlorin e6,CE6

Target: Parasite

Chlorin e6 trimethyl ester

T40435

Synonym:

Target:

Chlorophyllin sodium copper salt

T1254

Synonym: Chlorophyllin copper sodium complex,Chlorophyllin,Chlorophyllin coppered trisodium salt,Sodium-copper chlorin e6

Target: Others

Talaporfin sodium

T16978

Synonym: ME2906,NPe6,Mono-L-aspartyl chlorin e6

Synonym: BAY2353,Niclocide

Target: Antibiotic, STAT, Parasite

Amantadine hydrochloride

T1406

Synonym: 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride

Target: Dopamine Receptor, Influenza Virus

E6446 dihydrochloride

Synonym: E 6801,E-6801

Target: 5-HT Receptor

[D-p-Cl-Phe6,Leu17]-VIP acetate

TP2103L

Synonym:

Target: Others

Hexaethylene Glycol Monooctyl Ether (C8E6)

Synonym: Anti-MERS-2E6 mAb

Target:

(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)

Hexaethylene Glycol Monodecyl Ether (C10E6)

[D-p-Cl-Phe6,Leu17]-VIP TFA

T78003

Synonym:

Target:

Hexaethylene Glycol Monododecyl Ether (C12E6)

[D-p-Cl-Phe6,Leu17]-VIP

Synonym: (E/Z)-E64FC26

Target:

Me6TREN 4HCl

T33267

Synonym: Me6TREN Tetrahydrochloride,Me6-TREN Tetrahydrochloride,Me6 4HCl,Me 6 4HCl,Me-6 4HCl

Synonym: ABI-231,VERU-111

Target: Microtubule Associated

Target: Nucleoside Antimetabolite/Analog, Virus Protease, SARS-CoV, DNA/RNA Synthesis

Synonym: CCG 40788,RH-02007,CCG40788,CCG-40788,RH 02007

Synonym: BAY2353 sodium

Target:

SARS-CoV-2 3CLpro-IN-14

SARS-CoV-2 3CLpro-IN-18

HDAC4 CHDI Degrader 11

T83947

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T7060	Amantadine	1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine	Others
	Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.		Others
TN2149	Reynosin		BCL , Others , TNF
	Reynosin has hepatoprotective, and anti-inflammatory effects, it has protective effect against dopamine-induced neuronal cell death, which may be due to the reciprocal up-regulation of E6-associated protein and down-regu...		BCL , Others , TNF
T79941	Antimycin A2c		Apoptosis
	Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer. It impedes HeLa cell proliferation by arresting the cell cycle at the S phase and induces cas...		Apoptosis

Natural Products

Amantadine

T7060

Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine

Target: BCL, Others, TNF

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-01467	HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, ...
TMPK-01466	HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, ...
TMPH-01833	Human Papilloma Virus type 16 (HPV 16) Protein E6 (His)	HPV 16	P. pastoris (Yeast)
	Human Papilloma Virus type 16 (HPV 16) Protein E6 (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 21.2 kDa and the accession number is P03126.
TMPH-01832	Human Papilloma Virus type 16 (HPV 16) Protein E6 (E. coli, His)	HPV 16	E. coli
	Human Papilloma Virus type 16 (HPV 16) Protein E6 (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.2 kDa and the accession number is P03126.
TMPJ-01258	RNASE6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family. Human RNASE6 is synthesized as a 150 amino acid precursor that contains a 23 amino acid signal sequence, and a 127 amino ...
TMPH-02033	RPE65 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	RPE65 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus.
TMPY-02842	UBE2L6 Protein, Human, Recombinant (His)	Human	E. coli
	UBCH8, also known as UBE2L6, belongs to the ubiquitin-conjugating enzyme family. The family of ubiquitin-conjugating (E2) enzymes is characterized by the presence of a highly conserved ubiquitin-conjugating (UBC) domain....